April 1, 2013

Personalized Medicine for Alzheimer’s, Aneurysms

By Center for Individualized Medicine

Another case for the power of collaboration: The medical and research expertise of Mayo Clinic coupled with the bio and chemical engineering prowess of Arizona State University.

These teams are working together to unravel the genomic components of two frustratingly complex conditions -- Alzheimer's disease and cerebral aneurysms.

Terrone Rosenberry, Ph.D., and Pritam Das, Ph.D., both in the Department of Neuroscience at Mayo Clinic, together with Michael Sierks, ASU chemical engineering professor. The team is developing nanobodies to diagnose Alzheimer’s disease at an earlier stage than is possible now. What is a nanobody? It's a customized protein that binds to specific sites on the surface of cells and other proteins, similar to the naturally occuring antibodies that help the immune system identify a common cold, for instance.

Brian Chong, M.D., a neuroradiologist at Mayo Clinic, and David Frakes, ASU biological and health systems engineering professor. These two are developing software that will change the way treatment planning for cerebral aneurysms is managed.

ASU interviews their docs and summarizes the research. The Phoenix Business Journal covered the awards back in March.

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