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May 15, 2019

One year in, All of Us Research Program makes strides in diverse health research

By Colette Gallagher
All of Us Research Program Group

For far too long, biomedical research has been based on a small subset of the United States population, leading to prevention and treatment methods that are often one-size-fits-all. To address this issue, the National Institutes of Health All of Us Research Program is working to build a cohort of one million or more participant partners that reflects the diversity of the United States.

Program participants provide data and samples that will be broadly accessible to researchers for a wide range of studies. By taking into account individual differences, researchers will uncover paths toward delivering precision medicine — or individualized prevention, treatment, and care — for all of us.

May 6 marked one year from the program’s national launch. A Facebook live session,  “From Data to Discoveries: Creating a Research Program for All of Us,” was hosted by Francis Collins, M.D., Ph.D., director, National Institutes of Health. Dr. Collins identified the building blocks of a meaningful research program, including an engaged and diverse participant community, and forecasted the program’s scientific possibilities.

1st Year Milestones - All of Us Research Program Biobank at Mayo Clinic

Mayo Clinic is one of more than 100 organizations across the United States that is funded by the National Institutes of Health All of Us Research Program. In 2016, Mayo Clinic was awarded $142 million in funding over five years by the National Institutes of Health to serve as the program’s biobank.

"The All of Us Research Program biobank at Mayo Clinic has the capacity to store more than 35 million biospecimens.”

Since the launch of the program on May 6, 2018 several milestones have been reached.

“The All of Us Research Program biobank at Mayo Clinic has the capacity to store more than 35 million biospecimens,” says Stephen Thibodeau, Ph.D., co-principal investigator of the All of Us Research Program biobank funding award. “It is currently storing more than 3 million frozen vials from consented participants and has capacity to process samples from up to 1,500 participants per day.”

In addition to increasing lab space in Rochester and on the Mayo Clinic campus in Florida, the team ramped up equipment, built up its technical infrastructure, and has established a business continuity plan in the case of a catastrophic event.

“We expanded our laboratory operation to fully automate sample processing and sample storage,” says Mine Cicek, Ph.D., co-principal investigator and laboratory director, Mayo Clinic Biorepositories Program, Center for Individualized Medicine. “Our team continually monitors multiple indicators related to incoming specimen quality control events and provides feedback to enrollment sites.”

From hiring support staff to maintaining an education plan for program partners to providing 24/7 customer support the All of Us Research Program Biobank at Mayo Clinic works to enable precision medicine research to improve the health of the nation.

More information

For more information, visit the All of Us Research Program website.

Watch the Facebook Live session celebrating the program's one-year mark and hear from National Institutes of Health Director Francis Collins, M.D.:

Dr. Thibodeau is the David F. and Margaret T. Grohne Director, Mayo Clinic Biorepositories Program, Center for Individualized Medicine.
This work is supported under NIH funding award RFA-PM-16-004. 

“All of Us” is a registered service mark of the U.S. Department of Health and Human Services. For more information, visit www.JoinAllofUs.org and www.allofus.nih.gov.

Tags: All of Us Research Program, biobank, Dr. Mine Cicek, Dr. Stephen Thibodeau, mayo clinic, Mayo Clinic Center for Individualized Medicine, National Institutes of Health, Precision Medicine, Research

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