December 16, 2019

Mayo Clinic researchers look at post menopause as key factor in endometrial cancer

By Colette Gallagher

Mayo Clinic researchers have identified a microbiome signature associated with endometrial cancer, which is in part promoted by post menopause. In a study, supported by Mayo Clinic Center for Individualized Medicine and published in Scientific Reports, researchers sought to understand how endometrial cancer risk factors alter the reproductive tract microbiome and endometrial cancer risk.

“If the microbiome does play a role in endometrial cancer, beyond being a marker for it, this could have important implications for endometrial cancer prevention,” says Marina Walther-Antonio, Ph.D., lead author of the Mayo Clinic study.

Endometrial cancer is the most common gynecological malignancy in the U.S. and the fourth most common cancer among women. In addition, endometrial cancer incidence rates are on the rise in the western world, suggesting that alterations in environmental factors such as diet, lifestyle, and the vaginal microbiome may be important drivers in its cause.

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Tags: cancer, Endometrial cancer, microbiome, Microbiome Program, Uncategorized

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