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Sep 19, 2019

One Discovery Square - a hub for innovation, state-of-the-art labs, top researchers

By Sharon Rosen @sharonhrosen
Article by Susan Murphy Today, researchers, physicians and staff with the Advanced Diagnostics Laboratory, a joint collaboration between the Mayo Clinic Department of Laboratory Medicine and Pathology and the Center for Individualized Medicine, will take part in a community celebration of One Discovery Square from 4-6 p.m. The grand opening event, held in conjunction with the Destination [...]
One Discovery Square - a hub for innovation, state-of-the-art labs, top researchers
Sep 11, 2019

Improving genomic data analysis - from soybeans to humans

By Colette Gallagher @colettegallagher
Article by Colette Gallagher and Amy Clay-Moore When Daniel Wickland, Ph.D., was a predoctoral student at the University of Illinois at Urbana-Champaign, he first worked to improve genomic data analysis for soybeans. But soon he shifted his focus, bringing his computer programming and informatics skills to work with Mayo Clinic and Illinois researchers to better understand [...]
Improving genomic data analysis - from soybeans to humans
Sep 3, 2019

Shotgun metagenomics: A promising new method toward diagnosing infections

By Sharon Rosen @sharonhrosen
Article by Christoph Bahn This article originally appeared on Mayo Clinic Laboratories Insights. Shotgun metagenomic sequencing (aka “shotgun metagenomics”) is a revolutionary new way to detect infectious organisms. Currently, this technology is undergoing validation for clinical testing in Mayo Clinic’s Clinical Microbiology Laboratory. By sequencing all of the DNA (or RNA in [...]
Shotgun metagenomics: A promising new method toward diagnosing infections
Aug 29, 2019

Gerstner awards boost research into rheumatoid arthritis, breast cancer

By Barbara J. Toman @barbaratoman
Creating tools to identify optimal treatments for rheumatoid arthritis and breast cancer are focuses of the 2019 Gerstner Family Career Development Awards. This year's awardees are Elena Myasoedova, M.D., Ph.D., a rheumatologist at Mayo Clinic's Minnesota campus and Bhavika Patel, M.D., a radiologist at Mayo's Arizona campus. Both researchers seek [...]
Gerstner awards boost research into rheumatoid arthritis, breast cancer
Aug 27, 2019

Meet Margot Cousin, Ph.D.: Genetic detective, researcher, member of the A-team

By Sharon Rosen @sharonhrosen
When a young boy arrived at Mayo Clinic after repeatedly experiencing infections that caused a fever and a rapid loss of liver function, clinicians turned to genetic testing to find the cause of the illness. Margot Cousin, Ph.D., a translational genomics researcher in the Mayo Clinic Center for Individualized Medicine Translational Omics Program was among [...]
Meet Margot Cousin, Ph.D.: Genetic detective, researcher, member of the A-team
Aug 20, 2019

Genomics and computer science intersect to improve patient care

By Sharon Rosen @sharonhrosen
Computational genomics is a field that brings high-performance computing resources to drive precision medicine research toward new discoveries. However, when over 50 Mayo Clinic physicians, researchers and students gathered in June to participate in the Computational Genomics Course, the emphasis was on the needs of the patient. The annual week-long intensive [...]
Genomics and computer science intersect to improve patient care
Aug 15, 2019

Shaping the landscape of cancer care with precision therapies

By Sharon Rosen @sharonhrosen
Article by Sara Damore Jeffrey Tyner, Ph.D., associate professor in the Department of Cell & Developmental Biology at Oregon Health & Science University, will join several precision cancer care leaders from across the country at the annual Individualizing Medicine Conference. Dr. Tyner will present “Precision Therapy through Functional Genomics in Hematologic [...]
Shaping the landscape of cancer care with precision therapies
Aug 13, 2019

An artificial intelligence tool to improve pancreatic cancer outcomes

By Barbara J. Toman @barbaratoman
Only 9% of people with pancreatic cancer live for five years after diagnosis. "That is an abysmally low number, probably the worst in human cancers," says Michael Wallace, M.D., a digestive disease specialist and a researcher within the Center for Individualized Medicine at the Mayo Clinic campus in Florida. "We [...]
An artificial intelligence tool to improve pancreatic cancer outcomes
Aug 6, 2019

Meet Mukesh Pandey, Ph.D. - developing a new drug to detect prostate cancer in its earliest stages

By Sharon Rosen @sharonhrosen
With a background in organic chemistry, Mukesh Pandey, Ph.D., initially planned to work in the pharmaceutical industry developing medications. But after completing a post-doctoral research fellowship in radiology at Harvard Medical School, he chose to focus his skills on improving imaging technologies to better detect the first signs of disease. [...]
Meet Mukesh Pandey, Ph.D. - developing a new drug to detect prostate cancer in its earliest stages
Jul 30, 2019

Community voices guide use of biobank samples in research

By Sharon Rosen @sharonhrosen
Article by Caitlin Doran Mayo Clinic supports biobanks — large collections of patient biological samples—near each of its three campuses in Arizona, Florida and Minnesota, with the goal of advancing research to broaden the understanding of health and disease. Paired with each biobank, Mayo fields a community advisory board (CAB), whose [...]
Community voices guide use of biobank samples in research
Jul 25, 2019

Antoni Ribas, M.D., Ph.D. - leading melanoma researcher to speak at #CIMCON19

By Sharon Rosen @sharonhrosen
Article by Sara Damore Melanoma is an aggressive skin cancer caused by extensive sun exposure and the fifth most common cancer in the U.S. If detected and treated early, the survival rates for melanoma are high (98%). However, once the cancer spreads to other areas of the body, survival rates for malignant melanoma drop dramatically [...]
Antoni Ribas, M.D., Ph.D. - leading melanoma researcher to speak at #CIMCON19
Jul 23, 2019

From ancestry to health traits - how do I know if genetic testing may be right for me?

By Sharon Rosen @sharonhrosen
Article by Shannon Wieloch Last month we posted a blog on helpful tips to know before taking a DNA test. In part II of this topic, we delve deeper into the types of genetic testing commonly available to help you decide what type of testing may be right for you. Some genetic tests inform you about [...]
From ancestry to health traits - how do I know if genetic testing may be right for me?
Jul 18, 2019

Targeting therapy to each patient's unique cancer

By Sharon Rosen @sharonhrosen
Article by Sara Damore As DNA sequencing technology helps bring genetic factors driving disease into focus, researchers have developed new cancer therapies to target a patient’s unique cancer, especially for those who do not respond to standard therapy. Funda Meric-Bernstam, M.D., a physician-scientist at MD Anderson Cancer Center will speak on Decision [...]
Targeting therapy to each patient's unique cancer
Jul 16, 2019

Kentucky community hospital develops precision medicine program with help from Mayo Clinic

By Sharon Rosen @sharonhrosen
Article by Rachel Guibert and Alyson Gonzalez When staff at St. Elizabeth Healthcare in Kentucky — a Mayo Clinic Care Network member — decided that they wanted to bring precision medicine to their patients, they turned to Mayo Clinic for help. "We're a community hospital that doesn't have the [...]
Kentucky community hospital develops precision medicine program with help from Mayo Clinic
Jul 9, 2019

Mayo experts provide insights into how genes affect medication response

By Sharon Rosen @sharonhrosen
Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect [...]
Mayo experts provide insights into how genes affect medication response
Jun 28, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Barbara J. Toman @barbaratoman
By definition, personalized medicine requires diversity. One-size-fits-all doesn't work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic's Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo's medical research. Sangre [...]
Can BioBanks Help Close Gaps in Health Outcomes?
Jun 24, 2019

Medicine and Artificial Intelligence: Ethical Tensions

By Sharon Rosen @sharonhrosen
While artificial intelligence is already transforming health care by improving diagnostic accuracy and speeding the analysis of biological and genomics data to better understand disease, there are many ethical issues that should be considered. This was the message that Mayo Clinic bioethicist Richard Sharp, Ph.D., shared with attendees at the [...]
Medicine and Artificial Intelligence: Ethical Tensions
Jun 17, 2019

Considering a DNA test? Helpful tips before you take the plunge

By Sharon Rosen @sharonhrosen
Article by Shannon Wieloch The availability of genetic testing has exploded. You hear about it on television, the radio and the internet. Family members are verifying age-old stories of their ancestry. Co-workers are talking about the genes that predispose them to weigh 12% less than average. With everyone doing it, a consumer [...]
Considering a DNA test? Helpful tips before you take the plunge
Jun 10, 2019

Meet William Bobo, M.D. - taking the guesswork out of finding the right depression therapy

By Sharon Rosen @sharonhrosen
Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial [...]
Meet William Bobo, M.D. - taking the guesswork out of finding the right depression therapy
Jun 3, 2019

Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment

By Sharon Rosen @sharonhrosen
Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who can determine if [...]
Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment
May 29, 2019

Individualizing Medicine 2019 Conference - practical precision cancer care approaches for your patients

By Sharon Rosen @sharonhrosen
Amidst the demands of providing care for patients with cancer, it can be challenging for oncologists and their care teams to keep up with the rapidly evolving field of genomics. Practical ways to apply the latest precision medicine discoveries is the focus of this year’s Individualizing Medicine Conference: Precision Cancer [...]
Individualizing Medicine 2019 Conference - practical precision cancer care approaches for your patients
May 23, 2019

After nearly three decades of testing, genome-sequencing brings answers for Arizona family

By Sharon Rosen @sharonhrosen
Article by Lynn Closway At age 27, Kyle Christy has defied the odds. He was born with seemingly insurmountable medical challenges that caused his parents, Debra and Todd, to fear what their beloved first-born son’s life would be like. When their second son was born, just 19 months later, Debra and [...]
After nearly three decades of testing, genome-sequencing brings answers for Arizona family
May 15, 2019

One year in, All of Us Research Program makes strides in diverse health research

By Colette Gallagher @colettegallagher
For far too long, biomedical research has been based on a small subset of the United States population, leading to prevention and treatment methods that are often one-size-fits-all. To address this issue, the National Institutes of Health All of Us Research Program is working to build a cohort of one [...]
One year in, All of Us Research Program makes strides in diverse health research
May 7, 2019

Targeting bile duct cancer - meet Mitesh Borad, M.D.

By Sharon Rosen @sharonhrosen
The search for treatment targets for patients with bile duct cancer, also known as cholangiocarcinoma, has taken a 360 degree turn, offering new hope for patients. That’s according to Mitesh Borad, M.D., deputy director for Center for Individualized Medicine Biomarker Discovery Program at Mayo Clinic’s Arizona campus, Dr. Borad and his colleagues are using new [...]
Targeting bile duct cancer - meet Mitesh Borad, M.D.
Apr 30, 2019

Sudden Cardiac Death: Defining the Risk for Surviving Relatives

By Barbara J. Toman @barbaratoman
A young person's sudden death from cardiac arrest is doubly devastating. Just when family members are mourning the unexpected loss, they might also be wondering if the cause was inherited heart disease — and if they too are at risk. Often there's no easy answer. Unlike certain cancers with strong [...]
Sudden Cardiac Death: Defining the Risk for Surviving Relatives
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