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Nov 19, 2018

Gene therapy: potential and pitfalls

By Susan Buckles @susanbuckles
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food [...]
Gene therapy:  potential and pitfalls
Nov 12, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher @colettegallagher
Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report [...]
Novel data-driven approach for precision medicine
Nov 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen @sharonhrosen
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard [...]
Pharmacogenomics: finding the right drug, dose for cancer therapy
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