cancer

August 8, 2022

Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care

By Colette Gallagher Colette Gallagher (@colettegallagher)

Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic


August 1, 2022

New AI algorithm opens avenues for knowledge discoveries

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a proof-of-concept study published in Frontiers in Immunology, Hu Li, Ph.D., a Mayo Clinic Center for Individualized Medicine systems biologist, developed a new artificial intelligence (AI) algorithm which uses novel weight engineering methods to extract meaningful biological knowledge learned by AI models. He and his team applied the tool to breast cancer omic data […]

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Tags: Cancer Research, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine


July 20, 2022

2022 Gerstner Awardee to investigate gut microbiome link to chemotherapy-induced nausea

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Singh is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract. 

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Tags: center for individualized medicine, genomic medicine, genomics


July 20, 2022

2022 Gerstner Awardee to investigate dual CAR-T cell therapy for multiple myeloma cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Sakemura is working to advance immunotherapy efficacy in multiple myeloma cancer by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment. 

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Tags: center for individualized medicine, Genetics, genomics, individualized medicine, medical research, Multiple Myeloma


July 6, 2022

Do environmental exposures contribute to human diseases? 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers put the exposome under the microscope to understand links between lifelong exposures and diseases.

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Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, exposome, gene sequencing, Genetics, genomics


June 8, 2022

Mayo Clinic Cancer Center Patients, Executive Director Highlighted in American Association for Cancer Research Cancer Disparities Progress Report

By Colette Gallagher Colette Gallagher (@colettegallagher)

The American Association for Cancer Research today released its Cancer Disparities Progress Report 2022. The publication aims to raise awareness of the enormous toll that cancer exacts on racial and ethnic minorities and other diverse and medically underserved populations in the United States while highlighting areas of recent progress in reducing cancer health disparities. The […]

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Tags: Cancer Research, cancer screening, center for individualized medicine, health disparities, mayo clinic


May 5, 2022

Mayo research using DNA to catch cancer, other medical conditions earlier

By Adam Harringa Adam Harringa (@harringaadam)

What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]

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Tags: center for individualized medicine, DNA Testing, genomics, individualized medicine, mayo clinic, medical research


April 13, 2022

Mayo Clinic researchers load CAR-T cells with oncolytic virus to treat solid cancer tumors

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers at Mayo Clinic’s Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors. 

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Tags: #CAR T-cell therapy, center for individualized medicine, Dr. Richard Vile, genomics, individualized medicine, medical research, oncolytic virus, personalized medicine


March 31, 2022

Mayo Clinic patient grateful after genetic test leads to unexpected, early detection of colon cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Alejandro Mirazo, 56, never imagined his genetic test results would reveal a hereditary link to cancer, or that his findings would potentially save his life. He had participated in a preemptive DNA research sequencing study for Mayo Clinic’s Center for Individualized Medicine in fall 2021 solely to contribute to medical research. As a Mexican American, he also wanted to add diversity to Mayo Clinic’s genomic dataset.

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, medical research, personalized medicine


March 24, 2022

What you should know about genetics, colorectal cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Nicole Brudos Ferrara Colorectal cancer begins when healthy cells in the colon or rectum develop mutations, or changes, in their DNA. These damaged cells then become cancerous, grow and divide uncontrollably, and form a tumor. Genetic factors play a role in this process. Some gene mutations passed through generations of your family can increase […]

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Tags: center for individualized medicine, colon cancer, DNA Testing, Dr. Niloy "Jewel" Samadder, gene sequencing, Genetics, genomic medicine, hereditary colon cancer


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