November 27, 2023
Mayo Clinic study explores heart failure, uncovers gene’s role in recovery
Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments. The disease makes it harder for the heart’s left ventricle to pump blood effectively to the rest of the […]
November 10, 2023
Pass the turkey — and your family health insights — this Thanksgiving
By Susan Murphy
Thanksgiving Day is also Family Health History Day, an annual national campaign to promote awareness of hereditary health traits in families. Has your grandmother, mother, aunt or sister had breast or ovarian cancer? Has your grandfather, father or uncle had prostate, breast or pancreatic cancer? Is there a history in your family of colon cancer, diabetes […]
Tags: center for individualized medicine, Genetics, medical research
October 31, 2023
Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions
By Susan Murphy
Sisters often share certain genetic traits, such as hair color and facial features. But for three sisters from Minnesota, they discovered a much deeper connection — a shared genetic mutation known to dramatically increase their risk for breast and ovarian cancer. Their BRCA1 variants came to light through a Mayo Clinic Center for Individualized Medicine […]
September 12, 2023
New Mayo Clinic individualized medicine leader on a quest to bring cutting-edge medicine to all
By Susan Murphy
As a pulmonologist and genomic scientist, Victor Ortega, M.D., Ph.D., is leading a charge to breathe new life into precision medicine advancements. His mission is rooted in a deep commitment to health equities and inspired by his grandmother. “My grandmother died of asthma, and that should not have happened. She was Puerto Rican like me, […]
Tags: Biomedical research, center for individualized medicine, Dr. Victor Ortega, genomic medicine
August 31, 2023
Mayo Clinic cancer researchers targeting racial disparities in genomic data
By Susan Murphy
Standing at the forefront of Mayo Clinic’s genomics advancements, Yan Asmann, Ph.D., and Aaron Mansfield, M.D. are working to tailor the diagnosis and treatment of certain cancers to a person’s unique genomic makeup. As a bioinformatician, Dr. Asmann is pursuing individualized therapeutic cancer vaccines that target a person’s distinctive tumor characteristics. Dr. Mansfield, a […]
Tags: Biomedical research, center for individualized medicine
August 16, 2023
By Susan Murphy
When Emery Diffendorfer was a baby, he couldn’t hold his head up or babble like other infants his age. His rare genetic disorder enlarged his tongue and head, and he had weakened muscle tone, brittle bones, sleep apnea, poor eyesight and persistent infections in his tonsils and adenoids. By six months old, the tiny Mayo […]
Tags: Biomedical research
August 1, 2023
2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance
By Susan Murphy
Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]
Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer
July 24, 2023
CAR-T cell therapy restores hope for leukemia patient
Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says Stahlecker. “We had bought land […]
Tags: #CAR T-cell therapy, center for individualized medicine, Center for Regenerative Medicine
July 21, 2023
In a pilot study of 165 people, Mayo Clinic researchers looked at the effectiveness of two different approaches to weight loss: a standard lifestyle intervention and individualized therapy. The standard lifestyle intervention included a reduced diet, exercise and behavior therapy. The individualized approach was based on phenotypes and included different interventions depending on the person’s […]
Tags: Biomedical research, center for individualized medicine, Dr. Andres Acosta, genomic medicine, mayo clinic
July 3, 2023
Mayo Clinic discovery leads to diagnoses of 9 people with rare form of muscular dystrophy
By Susan Murphy
Nine people around the world who have been living with unexplained, muscular dystrophy-like symptoms may now have an answer for what is causing the progressive muscle weakness in their body’s mid-section, arms and legs. In a new discovery, a collaborative team of scientists led by researchers at Mayo Clinic’s Center for Individualized Medicine has pinpointed […]
Tags: Biomedical research, center for individualized medicine, Dr. Eric Klee, genomics