Mayo Clinic Center for Individualized Medicine

November 27, 2023

Mayo Clinic study explores heart failure, uncovers gene’s role in recovery

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments. The disease makes it harder for the heart’s left ventricle to pump blood effectively to the rest of the […]

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October 31, 2023

Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions

By Susan Murphy Susan Murphy (@susanmurphy)

Sisters often share certain genetic traits, such as hair color and facial features. But for three sisters from Minnesota, they discovered a much deeper connection — a shared genetic mutation known to dramatically increase their risk for breast and ovarian cancer. Their BRCA1 variants came to light through a Mayo Clinic Center for Individualized Medicine […]

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Tags: Dr. Konstantinos Lazaridis


October 18, 2023

17-gene signature linked to remission after triple-negative breast cancer treatment 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast Cancer Research, highlights the potential for further investigating this signature as a target for individualized medicine. 

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Tags: Biomedical research, center for individualized medicine, multi-omics


October 11, 2023

Mayo Clinic study sheds light on rare genetic disorder and blood cancers

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a recent study, Mayo Clinic researchers examined telomere biology disorders, a group of rare genetic disorders characterized by short telomeres. Telomeres are long segments at the end of chromosomes that protect the DNA from unraveling, similar to the small plastic sheath at the end of a shoelace. Telomeres shorten naturally with age but become […]

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September 18, 2023

Mayo Clinic researchers identify link between gut bacteria and pre-clinical autoimmunity and aging in rheumatoid arthritis

By Colette Gallagher Colette Gallagher (@colettegallagher)

While the bacteria in the intestine are helpful for digesting food and fighting infections, they have long been suspected to play an essential role in triggering rheumatoid arthritis. This chronic inflammatory disorder affects the joints. Mayo Clinic researchers have discovered a link between an abundance of specific gut bacteria and the triggering of an immune […]

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