Multi-omics

January 1, 2024

Mayo Clinic patients find hope in individualized medicine in 2023

By Susan Murphy Susan Murphy (@susanmurphy)

In a remarkable year of medical advancements and discoveries, the Mayo Clinic Center for Individualized Medicine has touched the lives of many patients. From groundbreaking treatments to life-changing diagnoses, the stories of these patients highlight the profound impact of Mayo Clinic’s innovative and personalized approaches. Here is a look back at some notable patient journeys from […]

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December 18, 2023

10 significant studies from Mayo Clinic’s Center for Individualized Medicine in 2023

By Susan Murphy Susan Murphy (@susanmurphy)

In 2023, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]

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Tags: center for individualized medicine


November 10, 2023

Pass the turkey — and your family health insights — this Thanksgiving

By Susan Murphy Susan Murphy (@susanmurphy)

Thanksgiving Day is also Family Health History Day, an annual national campaign to promote awareness of hereditary health traits in families. Has your grandmother, mother, aunt or sister had breast or ovarian cancer? Has your grandfather, father or uncle had prostate, breast or pancreatic cancer? Is there a history in your family of colon cancer, diabetes […]

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Tags: center for individualized medicine, Genetics, medical research


October 31, 2023

Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions

By Susan Murphy Susan Murphy (@susanmurphy)

Sisters often share certain genetic traits, such as hair color and facial features. But for three sisters from Minnesota, they discovered a much deeper connection — a shared genetic mutation known to dramatically increase their risk for breast and ovarian cancer. Their BRCA1 variants came to light through a Mayo Clinic Center for Individualized Medicine […]

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Tags: Dr. Konstantinos Lazaridis


October 18, 2023

17-gene signature linked to remission after triple-negative breast cancer treatment 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast Cancer Research, highlights the potential for further investigating this signature as a target for individualized medicine. 

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Tags: Biomedical research, center for individualized medicine, multi-omics


September 28, 2023

New gene markers detect Lynch syndrome-associated colorectal cancer, Mayo Clinic study

By Susan Murphy Susan Murphy (@susanmurphy)

By Kelley Luckstein Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy. Studies are underway to determine if these genetic markers are in stool samples and, if so, how this could lead to a non-invasive screening option for patients with Lynch […]

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Tags: center for individualized medicine, Dr. Niloy "Jewel" Samadder


August 16, 2023

Mayo Clinic researchers use new innovative technology to diagnose teen brothers with ultra-rare genetic disorder

By Susan Murphy Susan Murphy (@susanmurphy)

When Emery Diffendorfer was a baby, he couldn’t hold his head up or babble like other infants his age. His rare genetic disorder enlarged his tongue and head, and he had weakened muscle tone, brittle bones, sleep apnea, poor eyesight and persistent infections in his tonsils and adenoids.  By six months old, the tiny Mayo […]

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Tags: Biomedical research


August 1, 2023

2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance

By Susan Murphy Susan Murphy (@susanmurphy)

Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]

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Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer


July 3, 2023

Mayo Clinic discovery leads to diagnoses of 9 people with rare form of muscular dystrophy

By Susan Murphy Susan Murphy (@susanmurphy)

Nine people around the world who have been living with unexplained, muscular dystrophy-like symptoms may now have an answer for what is causing the progressive muscle weakness in their body’s mid-section, arms and legs. In a new discovery, a collaborative team of scientists led by researchers at Mayo Clinic’s Center for Individualized Medicine has pinpointed […]

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Tags: Biomedical research, center for individualized medicine, Dr. Eric Klee, genomics


June 1, 2023

Mayo’s Individualizing Medicine Conference highlights innovative new era of health care 

By Susan Murphy Susan Murphy (@susanmurphy)

Health care is experiencing a trailblazing phase of innovation, with individualized medicine at the forefront. The driving forces behind the transformation are technological advancements, omics discoveries and the emergence of direct-to-patient clinical trials.   “We’re really moving into an exciting new era where we’re increasingly designing therapeutics specific for individual patients, expanding access and truly impacting […]

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Tags: Biomedical research, center for individualized medicine, Genetics, genomic medicine


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