Multi-omics

January 18, 2022

Mayo’s COVID-19 Sequencing Command Center offers insights into ‘power of the virus’

By Susan Murphy Susan Murphy (@susanmurphy)

Tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19, is crucial for detecting and responding to emerging variants. A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of the extensive research and surveillance operation, conducting nearly 750 sequences of the COVID-19 virus each week.

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Tags: center for individualized medicine, covid-19, Dr. Konstantinos Lazaridis, Dr. Purna Kashyap, Genetic Sequencing, sequencing


December 28, 2021

10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021

By Susan Murphy Susan Murphy (@susanmurphy)

It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses. 

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics


December 17, 2021

Mayo Clinic researchers use AI, biomarkers to personalize rheumatoid arthritis treatment

By Susan Murphy Susan Murphy (@susanmurphy)

By Emily Blahnik Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research. The study focused on predicting the […]

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Tags: #Dr. Arjun Athreya, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, Rheumatoid Arthritis


November 30, 2021

The importance of individualized regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

Individualized screening, guided by artificial intelligence (AI) and biomarkers, can optimize the transformative potential of regenerative medicine, according to a Mayo Clinic study. The paper, published in Biomarkers in Medicine, maintains that using new scientific tools to match the right biotherapeutics to the right patient ushers in the era of achieving tailored regenerative care.

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November 17, 2021

Identifying inherited gene mutations in pancreatic cancer can lead to targeted therapies, better survival

By Susan Murphy Susan Murphy (@susanmurphy)

In the study, which was published in Clinical and Translational Gastroenterology, nearly 1 in 6 people diagnosed with pancreatic cancer were found to have an inherited cancer-related gene mutation that likely predisposed them to the disease. The most common genetic mutation was in the BRCA2 gene, known as a “breast cancer gene.”

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November 9, 2021

Joined at the hip: Genetic testing reveals shared cause of hip pain for 4 family members

By Susan Murphy Susan Murphy (@susanmurphy)

Before they went through testing at Mayo Clinic Laboratories, Barbara Domaille, Deborah Neville, Pamela Neville and Rylie Ronnenberg thought there could be a genetic connection to the hip problems they shared. After testing, they knew for sure. By Cory Pedersen As family members, Barbara Domaille, Deborah Neville, Pamela Neville and Rylie Ronnenberg share many things […]

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October 25, 2021

‘We’ve only just begun to glimpse what is possible’ — and more thought-provoking quotes from Mayo Clinic’s 10th Annual Individualizing Medicine Conference

By Susan Murphy Susan Murphy (@susanmurphy)

Genomics experts highlighted the latest cutting-edge precision medicine strategies to accelerate medical breakthroughs at the 10th Annual Mayo Clinic Individualizing Medicine Conference. More than 350 researchers, clinicians and health care workers from across the world attended the virtual conference to learn firsthand how scientists are advancing the frontiers of individualized medicine. “We truly now have […]

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Tags: artificial intelligence, cancer genomics, genomic medicine, individualized medicine


October 18, 2021

Large-scale exome sequencing project spots disease-fueling mutations to save lives, accelerate discoveries

By Susan Murphy Susan Murphy (@susanmurphy)

When Michelle Ewy, 38, received an opportunity at Mayo Clinic to get her DNA tested for genetic mutations related to breast and ovarian cancers, and other cancers and diseases, she jumped at the chance.  “I wasn’t thinking much of what the outcome would be because there has not been a prevalence of breast or ovarian […]

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Tags: BRCA2, breast cancer, Dr. Konstantinos Lazaridis, Genetic Counseling, Genetic Testing, ovarian cancer, Teresa Kruisselbrink, whole exome sequencing


September 14, 2021

Mayo researchers link gut microbiome to rheumatoid arthritis prognosis

By Susan Murphy Susan Murphy (@susanmurphy)

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]

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Tags: #Dr. Jaeyun Sung, Dr. John Davis, genomics, microbiome, Rheumatoid Arthritis


August 30, 2021

2021 Gerstner Awardees to investigate individualized medicine approaches for heart attack and leukemia

By Susan Murphy Susan Murphy (@susanmurphy)

Moritz Binder M.D., a physician-scientist in Mayo Clinic’s divisions of Hematology and Oncology, and Satsuki Yamada, M.D., Ph.D., a physician-scientist in the division of Cardiovascular Diseases, are recipients of the 2021 Gerstner Family Career Development Awards.  The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to […]

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