Multi-omics
March 6, 2023
Unique Mayo team helping to move ‘omics’ science forward to transform patient care
By Susan Murphy 
Behind the front lines of Mayo Clinic researchers who are working to cure cancer and other diseases with “omics” data is a specialized team of translational science experts helping to push these intensive experiments across the finish line. One of these translational clinical scientists is Jan Egan, Ph.D., in Mayo Clinic’s Center for Individualized Medicine […]
Tags: center for individualized medicine, Genetics, genomic medicine, medical research
February 27, 2023
Mayo Clinic discovery leads to life-changing treatment for young girl with ultra-rare disease
By Susan Murphy
Months after young Maggie Carmichael started taking an experimental drug for her ultra-rare genetic disease, she was able to trade in her wheelchair for a walker. The 9-year-old Mayo Clinic patient even took a few of her first-ever steps on her own. She also became better at feeding herself, her speech improved and she started coloring in the lines.
Tags: #Dr. Eva Morava-Kozicz, center for individualized medicine, DNA Testing, genomic medicine, personalized medicine
February 6, 2023
Mayo researchers are moving ‘omics’ clinical trials from clinic to people’s homes
By Susan Murphy
An innovative way to conduct genomics research is underway to transition some omics-related studies out of hospitals, labs, and clinics to take them directly to people in their homes and communities. At Mayo Clinic’s Center for Individualized Medicine, clinical trial study staff including coordinators, physicians and scientists, are working hard to increase trial access for […]
Tags: center for individualized medicine, genomic medicine, genomics, medical research
January 10, 2023
Accelerating microbiome research in endometrial cancer
By Susan Murphy
By Alumni Magazine Marina Walther-Antonio, Ph.D., Departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, is a pioneer in studying the role of the microbiome in women’s health. Dr. Walther-Antonio is also Dean of Diversity, Equity and Inclusion in the Mayo Clinic Graduate School of Biomedical Science and an assistant professor in the Mayo Clinic College […]
Tags: center for individualized medicine, Dr. Marina Walther-Antonio, Endometrial cancer, genomic medicine
January 4, 2023
Advancing precision and predictive medicine in rheumatoid arthritis
By Susan Murphy
By Alumni Magazine Most patients who are diagnosed with rheumatoid arthritis respond to either the first or second line of drug therapies. However, some patients try multiple drugs without improve ment in their condition. It can take as long as two years of suffering, disease progression and expense before landing on a medication they respond to. […]
Tags: center for individualized medicine, gene sequencing, genomic medicine, personalized medicine, Rheumatoid Arthritis
December 28, 2022
3 impactful Mayo Clinic cancer research studies of 2022
By Susan Murphy
In 2022, Mayo Clinic physicians and scientists interrogated the genome, exome, proteome, epigenome, exposome, transcriptome and more with remarkable depth to shed new light on the hidden biological signatures of cancer. Using artificial intelligence and a wealth of multi-omics data, the pioneering teams of researchers worked side by side to pave a path for potential […]
Tags: center for individualized medicine, Genetics, genomic medicine, personalized medicine
December 2, 2022
The future will be personalized: Accelerating microbiome research
By Susan Murphy
By Mayo Clinic Alumni Magazine contributor We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings […]
November 10, 2022
Multi-omics: A new model for identifying biomarkers to predict severe COVID-19 outcomes
In a groundbreaking study published in The Lancet Digital Health, Mayo Clinic investigators have developed a multiomic molecular method to predict clinical COVID-19 (SARS-CoV-2) outcomes better than traditional cytokines. Using a machine-learning-based prediction model, the team identified 102 biomarkers, which include several novel cytokines and other proteins, lipids, and metabolites. The discovery may help clinicians reliably […]
Tags: covid-19
November 4, 2022
By Susan Murphy
The latest advances in exposomics, precision nutrition, metabolomics and cancer genomics were showcased on day two of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. More than 300 genomics experts and health care leaders gathered to share their latest research and visions for transforming human health through individualized medicine. Among the featured speakers […]
November 3, 2022
By Susan Murphy
World-leading scientists highlighted their “exposomics” knowledge and discoveries during the first day of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. Exposomics is the study of a person’s cumulative environmental exposures over their lifetime, called the exposome, and the associated inherent biological responses to those exposures. Environmental factors are associated with more than […]