pharmacogenomics
January 24, 2023
Could antidepressants cause treatment-emergent mania?
In a study published in Molecular Psychiatry, Mark Frye, M.D., a Mayo Clinic researcher and collaborators, investigated the risk of treatment-emergent mania in bipolar disorder when treated with antidepressants. “We found that antidepressants that increase mitochondrial energetics (cells that extract energy from nutrients for sustaining life) may elevate the risk of treatment-emergent mania,” says Dr. […]
Tags: center for individualized medicine, mayo clinic, personalized medicine
November 3, 2022
By Susan Murphy 
World-leading scientists highlighted their “exposomics” knowledge and discoveries during the first day of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. Exposomics is the study of a person’s cumulative environmental exposures over their lifetime, called the exposome, and the associated inherent biological responses to those exposures. Environmental factors are associated with more than […]
September 22, 2022
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research
March 22, 2022
The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.
Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics
March 16, 2022
Mayo Clinic researchers use AI to predict antidepressant outcomes in youth
Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.
Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine
January 27, 2022
Navigating Life’s Journey with the Right Topographical Map
By Susan Murphy
Combining genetic sequencing, life-style modification, and personalized drug therapy will transform health care. John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article. While still prevalent, the one-size-fits-all health care is slowly giving way to a more precise, personalized approach that takes into […]
December 28, 2021
10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021
By Susan Murphy
It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses.
Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics
December 17, 2021
Mayo Clinic researchers use AI, biomarkers to personalize rheumatoid arthritis treatment
By Susan Murphy
By Emily Blahnik Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research. The study focused on predicting the […]
Tags: #Dr. Arjun Athreya, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, Rheumatoid Arthritis
May 4, 2021
Mayo Clinic Center for Individualized Medicine refreshes website
The Mayo Clinic Center for Individualized Medicine website was recently updated to reflect Mayo Clinic’s continued focus on integrating precision medicine into the practice to improve patient care. In the last decade, Mayo Clinic researchers, physicians, and staff in the Center have been collaborating closely in a comprehensive team science approach to push the boundaries […]
Tags: mayo clinic, Mayo Clinic Center for Individualized Medicine
March 23, 2021
Mayo Clinic researchers explore personalized approach to anti-obesity medications
Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]
Tags: #Dr. Andres Acosta, #obesity, journal obesity, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, Precision Medicine