pharmacogenomics

March 22, 2022

Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes

By Colette Gallagher Colette Gallagher (@colettegallagher)

The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.

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Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics


March 16, 2022

Mayo Clinic researchers use AI to predict antidepressant outcomes in youth

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine


January 27, 2022

Navigating Life’s Journey with the Right Topographical Map

By Susan Murphy Susan Murphy (@susanmurphy)

Combining genetic sequencing, life-style modification, and personalized drug therapy will transform health care. John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article. While still prevalent, the one-size-fits-all health care is slowly giving way to a more precise, personalized approach that takes into […]

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December 28, 2021

10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021

By Susan Murphy Susan Murphy (@susanmurphy)

It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses. 

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics


December 17, 2021

Mayo Clinic researchers use AI, biomarkers to personalize rheumatoid arthritis treatment

By Susan Murphy Susan Murphy (@susanmurphy)

By Emily Blahnik Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research. The study focused on predicting the […]

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Tags: #Dr. Arjun Athreya, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, Rheumatoid Arthritis


May 4, 2021

Mayo Clinic Center for Individualized Medicine refreshes website

By Colette Gallagher Colette Gallagher (@colettegallagher)

The Mayo Clinic  Center for Individualized Medicine website was recently updated to reflect Mayo Clinic’s continued focus on integrating precision medicine into the practice to improve patient care. In the last decade, Mayo Clinic researchers, physicians, and staff in the Center have been collaborating closely in a comprehensive team science approach to push the boundaries […]

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Tags: mayo clinic, Mayo Clinic Center for Individualized Medicine


March 23, 2021

Mayo Clinic researchers explore personalized approach to anti-obesity medications

By Colette Gallagher Colette Gallagher (@colettegallagher)

Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]

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Tags: #Dr. Andres Acosta, #obesity, journal obesity, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, Precision Medicine


December 24, 2020

2020 Mayo Clinic Precision Medicine Advances

By Susan Murphy Susan Murphy (@susanmurphy)

This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]

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Tags: #Artificial Intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research


August 25, 2020

Largest pharmacogenetics clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy

By Susan Murphy Susan Murphy (@susanmurphy)

By Terri Malloy Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in […]

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Tags: #cardiology, Cardiovascular Disease, individualized medicine, pharmacogenomics


March 10, 2020

How pharmacogenomics can improve the lives of persons living with HIV

By Susan Murphy Susan Murphy (@susanmurphy)

By Jessica Fenske Life with HIV typically means using any number of medications to control the virus. But not all medications are the same or act the same way in different people. Mayo researchers are zeroing in on a new test to help patients fine-tune their treatments. While there is no cure for HIV, there […]

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Tags: pharmacogenomics, Research


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