pharmacogenomics

November 3, 2022

Trailblazing exposome researchers take center stage at Mayo Clinic’s Individualizing Medicine Conference

By Susan Murphy Susan Murphy (@susanmurphy)

World-leading scientists highlighted their “exposomics” knowledge and discoveries during the first day of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. Exposomics is the study of a person’s cumulative environmental exposures over their lifetime, called the exposome, and the associated inherent biological responses to those exposures. Environmental factors are associated with more than […]

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September 22, 2022

Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research


March 22, 2022

Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes

By Colette Gallagher Colette Gallagher (@colettegallagher)

The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.

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Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics


March 16, 2022

Mayo Clinic researchers use AI to predict antidepressant outcomes in youth

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine


January 27, 2022

Navigating Life’s Journey with the Right Topographical Map

By Susan Murphy Susan Murphy (@susanmurphy)

Combining genetic sequencing, life-style modification, and personalized drug therapy will transform health care. John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article. While still prevalent, the one-size-fits-all health care is slowly giving way to a more precise, personalized approach that takes into […]

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December 28, 2021

10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021

By Susan Murphy Susan Murphy (@susanmurphy)

It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses. 

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics


December 17, 2021

Mayo Clinic researchers use AI, biomarkers to personalize rheumatoid arthritis treatment

By Susan Murphy Susan Murphy (@susanmurphy)

By Emily Blahnik Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research. The study focused on predicting the […]

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Tags: #Dr. Arjun Athreya, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, Rheumatoid Arthritis


May 4, 2021

Mayo Clinic Center for Individualized Medicine refreshes website

By Colette Gallagher Colette Gallagher (@colettegallagher)

The Mayo Clinic  Center for Individualized Medicine website was recently updated to reflect Mayo Clinic’s continued focus on integrating precision medicine into the practice to improve patient care. In the last decade, Mayo Clinic researchers, physicians, and staff in the Center have been collaborating closely in a comprehensive team science approach to push the boundaries […]

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Tags: mayo clinic, Mayo Clinic Center for Individualized Medicine


March 23, 2021

Mayo Clinic researchers explore personalized approach to anti-obesity medications

By Colette Gallagher Colette Gallagher (@colettegallagher)

Individualized medicine initiatives mainly focus on rare diseases or cancer. Little has been attempted to individualize treatment for noncommunicable chronic diseases such as obesity — a chronic, relapsing disease, and a primary cause of Type 2 diabetes, fatty liver disease, cardiovascular disease and cancer. There are many obesity interventions, such as diets, devices, surgery and […]

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Tags: #Dr. Andres Acosta, #obesity, journal obesity, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics, Precision Medicine


December 24, 2020

2020 Mayo Clinic Precision Medicine Advances

By Susan Murphy Susan Murphy (@susanmurphy)

This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]

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Tags: #Artificial Intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research


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