Precision Medicine

January 1, 2024

Mayo Clinic patients find hope in individualized medicine in 2023

By Susan Murphy Susan Murphy (@susanmurphy)

In a remarkable year of medical advancements and discoveries, the Mayo Clinic Center for Individualized Medicine has touched the lives of many patients. From groundbreaking treatments to life-changing diagnoses, the stories of these patients highlight the profound impact of Mayo Clinic’s innovative and personalized approaches. Here is a look back at some notable patient journeys from […]

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December 26, 2023

Patient turns to Mayo Clinic to defy a family legacy of early heart attack deaths

By Susan Murphy Susan Murphy (@susanmurphy)

Brandon Wilson was just 7 years old when his father died of a heart attack. It marked the beginning of a sorrowful pattern, with almost all the men in his family dying of heart attacks before reaching the age of 40. Most recently, his older brother Teddy passed away after having five heart attacks. Since […]

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Tags: #Familial hypercholesterolemia, center for individualized medicine


December 18, 2023

10 significant studies from Mayo Clinic’s Center for Individualized Medicine in 2023

By Susan Murphy Susan Murphy (@susanmurphy)

In 2023, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]

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Tags: center for individualized medicine


December 8, 2023

Mayo Clinic’s biomedical ethics team reaches milestone in patient-centered research  

By Susan Murphy Susan Murphy (@susanmurphy)

As scientists at the Mayo Clinic Center for Individualized Medicine discover new ways to use genomic information in the diagnosis, treatment and prevention of disease, their progress will touch the lives of many Mayo Clinic patients.   Since its inception, the center has recognized the importance of understanding the experiences of people who undergo genomic evaluation. […]

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Tags: center for individualized medicine, Dr. Richard Sharp


November 10, 2023

Pass the turkey — and your family health insights — this Thanksgiving

By Susan Murphy Susan Murphy (@susanmurphy)

Thanksgiving Day is also Family Health History Day, an annual national campaign to promote awareness of hereditary health traits in families. Has your grandmother, mother, aunt or sister had breast or ovarian cancer? Has your grandfather, father or uncle had prostate, breast or pancreatic cancer? Is there a history in your family of colon cancer, diabetes […]

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Tags: center for individualized medicine, Genetics, medical research


October 31, 2023

Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions

By Susan Murphy Susan Murphy (@susanmurphy)

Sisters often share certain genetic traits, such as hair color and facial features. But for three sisters from Minnesota, they discovered a much deeper connection — a shared genetic mutation known to dramatically increase their risk for breast and ovarian cancer. Their BRCA1 variants came to light through a Mayo Clinic Center for Individualized Medicine […]

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Tags: Dr. Konstantinos Lazaridis


October 18, 2023

17-gene signature linked to remission after triple-negative breast cancer treatment 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast Cancer Research, highlights the potential for further investigating this signature as a target for individualized medicine. 

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Tags: Biomedical research, center for individualized medicine, multi-omics


October 5, 2023

Mayo Clinic research uncovers epigenetic roots of digestive disorder associated with diabetes

By Susan Murphy Susan Murphy (@susanmurphy)

Living with diabetes can be challenging due to numerous potential complications, including the development of gastroparesis. The digestive disorder, which predominantly affects women, leads to a delay in stomach emptying, causing nausea, vomiting and feeling full.  In a new preclinical study, scientists at the Mayo Clinic Center for Individualized Medicine have discovered insights into the […]

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Tags: center for individualized medicine, Diabetes research, Epigenetic research


September 28, 2023

New gene markers detect Lynch syndrome-associated colorectal cancer, Mayo Clinic study

By Susan Murphy Susan Murphy (@susanmurphy)

By Kelley Luckstein Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy. Studies are underway to determine if these genetic markers are in stool samples and, if so, how this could lead to a non-invasive screening option for patients with Lynch […]

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Tags: center for individualized medicine, Dr. Niloy "Jewel" Samadder


September 18, 2023

Mayo Clinic researchers identify link between gut bacteria and pre-clinical autoimmunity and aging in rheumatoid arthritis

By Colette Gallagher Colette Gallagher (@colettegallagher)

While the bacteria in the intestine are helpful for digesting food and fighting infections, they have long been suspected to play an essential role in triggering rheumatoid arthritis. This chronic inflammatory disorder affects the joints. Mayo Clinic researchers have discovered a link between an abundance of specific gut bacteria and the triggering of an immune […]

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