Precision Medicine

January 18, 2022

Mayo’s COVID-19 Sequencing Command Center offers insights into ‘power of the virus’

By Susan Murphy Susan Murphy (@susanmurphy)

Tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19, is crucial for detecting and responding to emerging variants. A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of the extensive research and surveillance operation, conducting nearly 750 sequences of the COVID-19 virus each week.

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Tags: center for individualized medicine, covid-19, Dr. Konstantinos Lazaridis, Dr. Purna Kashyap, Genetic Sequencing, sequencing


January 12, 2022

Mayo Clinic researchers discover biomarker for predicting immunotherapy response in mesothelioma cancer 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic Center for Individualized Medicine researchers may have discovered a genomic signature to predict which patients with mesothelioma could benefit from immunotherapy.  

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Tags: #mesothelioma, cancer, Cancer Research, center for individualized medicine, Genetics, genomics


December 28, 2021

10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021

By Susan Murphy Susan Murphy (@susanmurphy)

It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses. 

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics


December 22, 2021

Global study finds metabolic syndrome increased risk of acute respiratory distress syndrome, death in patients hospitalized with COVID-19

By Colette Gallagher Colette Gallagher (@colettegallagher)

Patients hospitalized with COVID-19 who had a combination of high blood pressure, obesity, diabetes, or other conditions associated with metabolic syndrome were at much higher risk of acute respiratory distress syndrome and death, according to an international study published in JAMA Network Open.

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Tags: center for individualized medicine, covid-19


December 17, 2021

Mayo Clinic researchers use AI, biomarkers to personalize rheumatoid arthritis treatment

By Susan Murphy Susan Murphy (@susanmurphy)

By Emily Blahnik Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research. The study focused on predicting the […]

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Tags: #Dr. Arjun Athreya, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, Rheumatoid Arthritis


December 15, 2021

Mayo Clinic research finds immune system responds to mRNA treatment for cancer

By Colette Gallagher Colette Gallagher (@colettegallagher)

Adding messenger RNA, or mRNA therapy improves the response to cancer immunotherapy in patients who weren’t responding to the treatment, Mayo Clinic research shows. Immunotherapy uses the body’s immune system to prevent, control and eliminate cancer. The study is published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

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Tags: cancer immunotherapy, Dr. Haidong Dong, gene therapy, genetic diseases, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine, mRNA therapy, Precision Medicine, Research


December 7, 2021

Pushing the Limits of Gene Therapy

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Ackerman is part of a cadre of researchers at Mayo Clinic who are pushing the limits of what is possible with gene therapy. They are looking beyond simply saving lives to improving the quality of life for people dealing with heart disease, liver disease and arthritis.

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November 30, 2021

The importance of individualized regenerative medicine

By Susan Buckles Susan Buckles (@susanbuckles)

Individualized screening, guided by artificial intelligence (AI) and biomarkers, can optimize the transformative potential of regenerative medicine, according to a Mayo Clinic study. The paper, published in Biomarkers in Medicine, maintains that using new scientific tools to match the right biotherapeutics to the right patient ushers in the era of achieving tailored regenerative care.

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November 22, 2021

Gather your family health history this Thanksgiving; it could save your life

By Susan Murphy Susan Murphy (@susanmurphy)

Thanksgiving Day marks Family Health History Day, an annual national public health campaign to encourage people to better understand what health characteristics run in their families. Has your mother, sister or grandmother had breast or ovarian cancer? Has your father had prostate cancer? Is there a history of colon cancer, diabetes or high cholesterol in your family? If so, you also could be at risk. John Presutti, D.O., a Mayo Clinic family medicine physician, says don’t just talk about your family health history. Act on it. It could save your life.

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Tags: center for individualized medicine


November 17, 2021

Identifying inherited gene mutations in pancreatic cancer can lead to targeted therapies, better survival

By Susan Murphy Susan Murphy (@susanmurphy)

In the study, which was published in Clinical and Translational Gastroenterology, nearly 1 in 6 people diagnosed with pancreatic cancer were found to have an inherited cancer-related gene mutation that likely predisposed them to the disease. The most common genetic mutation was in the BRCA2 gene, known as a “breast cancer gene.”

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