Precision Medicine

December 2, 2022

The future will be personalized: Accelerating microbiome research

By Susan Murphy Susan Murphy (@susanmurphy)

By Mayo Clinic Alumni Magazine contributor We’re in the midst of a microbiome research epidemic, according to Purna Kashyap, M.B.B.S., co-associate director of the Microbiome Program in the Mayo Clinic Center for Individualized Medicine. “We started early and are pushing hard,” says Dr. Kashyap. “We’re one of the top accelerators in the field and are well poised to move microbiome research findings […]

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Tags: Dr. Nicholas Chia, Dr. Purna Kashyap


November 22, 2022

Gather your family health history this Thanksgiving; it could save your life

By Susan Murphy Susan Murphy (@susanmurphy)

Thanksgiving Day marks Family Health History Day, an annual national public health campaign to encourage people to better understand what health characteristics run in their families. Has your mother, sister or grandmother had breast or ovarian cancer? Has your father had prostate cancer? Is there a history of colon cancer, diabetes or high cholesterol in your family? If so, you also could be at risk.

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Tags: center for individualized medicine, DNA Testing, Genetics, genomic medicine


November 18, 2022

New tool brings Mayo Clinic researchers closer to discovering therapeutics from microbiome

By Susan Murphy Susan Murphy (@susanmurphy)

Does the human microbiome inhabit a natural pharmacy? Microorganisms are found in tissues and biofluids throughout the body, including in and around the gut, lungs, nose, mouth, skin and vagina. A flurry of recent scientific research suggests that this human microbiome — a community of trillions of bacteria, viruses and fungi — is a driver […]

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Tags: #Dr. Jaeyun Sung, center for individualized medicine, genomic medicine, personalized medicine


November 10, 2022

Multi-omics: A new model for identifying biomarkers to predict severe COVID-19 outcomes 

By Chris J. Bahnsen Chris J. Bahnsen (@cjbahnsen)

In a groundbreaking study published in The Lancet Digital Health, Mayo Clinic investigators have developed a multiomic molecular method to predict clinical COVID-19 (SARS-CoV-2) outcomes better than traditional cytokines. Using a machine-learning-based prediction model, the team identified 102 biomarkers, which include several novel cytokines and other proteins, lipids, and metabolites. The discovery may help clinicians reliably […]

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Tags: covid-19


November 4, 2022

Day 2: Genomics experts share latest exposomic research at Mayo Clinic’s Individualizing Medicine Conference 

By Susan Murphy Susan Murphy (@susanmurphy)

The latest advances in exposomics, precision nutrition, metabolomics and cancer genomics  were showcased on day two of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. More than 300 genomics experts and health care leaders gathered to share their latest research and visions for transforming human health through individualized medicine.   Among the featured speakers […]

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November 3, 2022

Trailblazing exposome researchers take center stage at Mayo Clinic’s Individualizing Medicine Conference

By Susan Murphy Susan Murphy (@susanmurphy)

World-leading scientists highlighted their “exposomics” knowledge and discoveries during the first day of Mayo Clinic’s 11th Annual Individualizing Medicine Conference in Rochester, Minnesota. Exposomics is the study of a person’s cumulative environmental exposures over their lifetime, called the exposome, and the associated inherent biological responses to those exposures. Environmental factors are associated with more than […]

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November 1, 2022

Lab-grown ‘mini brains’ help Mayo Clinic scientists shed light on therapeutic targets for opioid addiction 

By Susan Murphy Susan Murphy (@susanmurphy)

Unimaginable a decade ago, Mayo Clinic scientists have developed lab-grown miniature 3D brain models out of human cells to study opioid addiction and opioid treatment response. As a result, the team has discovered changes in specific brain cells of people diagnosed with opioid use disorder when compared to those without the addiction disease.   The new […]

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Tags: brain organoids, center for individualized medicine, medical research


October 25, 2022

Trailblazing scientists discuss advances in exposome research, precision nutrition at Mayo Clinic’s Individualizing Medicine Conference   

By Susan Murphy Susan Murphy (@susanmurphy)

ROCHESTER, Minn. – The next frontier in individualized medicine is here. Mayo Clinic’s 11th annual Individualizing Medicine Conference on Nov. 2–3 will focus on “Exploring the Exposome” — the cumulative measure of environmental influences and associated biological responses throughout the life span of a person, and how those exposures relate to health and disease.    “We’ve […]

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October 25, 2022

Research provides critical information about the size and growth speed of gliomas

By Susan Murphy Susan Murphy (@susanmurphy)

By Kelley Luckstein An important new clue for preventing and treating brain tumors known as gliomas has been identified in research led by the Lunenfeld-Tannenbaum Research Institute (LTRI) at Mount Sinai Hospital in Toronto and Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine. The study, published in the journal Science, provides a rare window into the biological changes behind glioma development. […]

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October 18, 2022

Novel suppression-replacement preclinical gene therapy study shows promise in long and short QT syndromes

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS). LQTS is a genetic heart disease that can potentially cause fast, chaotic heartbeats. These rapid heartbeats might trigger people to […]

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Tags: center for individualized medicine, gene therapy, genomic medicine, individualized medicine, mayo clinic, personalized medicine


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