Precision Medicine

September 14, 2021

Mayo researchers link gut microbiome to rheumatoid arthritis prognosis

By Susan Murphy Susan Murphy (@susanmurphy)

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]

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Tags: #Dr. Jaeyun Sung, Dr. John Davis, genomics, microbiome, Rheumatoid Arthritis


September 7, 2021

Precision cancer advancements to take center stage at 10th annual Individualizing Medicine Conference

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers are taking a distinctive all-hands-on-deck approach to cancer, driven by advanced genetic analysis and clinical sciences to personalize treatments for every cancer patient. Clinicians and researchers work side by side, developing groundbreaking therapies to provide patients with answers, treatment options and optimism. This year’s virtual Mayo Clinic Individualizing Medicine Conference on Oct. […]

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Tags: cancer genomics, Cancer Research, individualized medicine, Individualized Medicine Conference 2016


August 31, 2021

New executive director for Mayo’s Center for Individualized Medicine shares vision of further advancing genomic medicine into patient care

By Susan Murphy Susan Murphy (@susanmurphy)

Konstantinos Lazaridis, M.D., known for his significant contributions in genomic research and medicine in a quest to predict and better diagnose disease, as well as devise individualized treatments, has been named the Carlson and Nelson Endowed Executive Director for Mayo Clinic’s Center for Individualized Medicine. The center is widely recognized as one of the most […]

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Tags: cancer genomics, Dr. Konstantinos Lazaridis, genomics, individualized medicine, multi-omics, rare disease


August 30, 2021

2021 Gerstner Awardees to investigate individualized medicine approaches for heart attack and leukemia

By Susan Murphy Susan Murphy (@susanmurphy)

Moritz Binder M.D., a physician-scientist in Mayo Clinic’s divisions of Hematology and Oncology, and Satsuki Yamada, M.D., Ph.D., a physician-scientist in the division of Cardiovascular Diseases, are recipients of the 2021 Gerstner Family Career Development Awards.  The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to […]

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August 24, 2021

A new understanding of the inner workings of CAR-T cell therapy

By Susan Buckles Susan Buckles (@susanbuckles)

Mayo Clinic researchers have biomanufactured chimeric antigen receptor-T cell therapy  (CAR-T cell therapy) in a new way to track the cells’ cancer fighting journey and predict toxic side effects. This Mayo Clinic breakthrough, published in Cancer Immunology Research, also could unravel the mystery of how to unleash CAR-T cell therapy to destroy solid tumors. “This […]

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Tags: #CAR T-cell therapy, Cancer Research


August 9, 2021

Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome

By Colette Gallagher Colette Gallagher (@colettegallagher)

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Tags: center for individualized medicine, Dr. Purna Kashyap, Genetics, mayo clinic, medical research, microbiome, personalized medicine


August 5, 2021

A “sandbox” for innovation: The Advanced Diagnostics Laboratory

By Christoph Bahn Christoph Bahn (@cjbahnsen)

The Advanced Diagnostics Laboratory (ADL) is a visionary space designed to continue Mayo Clinic’s long tradition of pioneering patient treatments and diagnostics. The ADL’s mission is to foster innovation — including grassroots innovation — across different specialties, through partnerships in-house as well as with external companies. Located on the third floor of One Discovery Square in a 9,600-square-foot […]

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Tags: Mayo Clinic Advanced Diagnostic Laboratory


July 21, 2021

Researchers review how sex steroids change gut, vaginal microbiome

By Colette Gallagher Colette Gallagher (@colettegallagher)

It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]

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Tags: Dr. Marina Walther-Antonio, Gut Microbiome, Mayo Clinic Center for Individualized Medicine, vaginal microbiome


July 8, 2021

New biorepository will serve as critical resource

By Susan Murphy Susan Murphy (@susanmurphy)

By Julie Janovsky-Mason Mayo Clinic is several months away from opening the doors to its new biorepository on the Phoenix campus. The facility will serve as a central resource to store and process biological specimens and clinical data for researchers working to develop therapeutics, vaccines and other medical advances. The planned 16,000-square-foot facility is the […]

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Tags: Biorepository, bioresearch, Dr. Aleksandar Sekulic, Dr. Stephen Thibodeau


July 1, 2021

Newly discovered genetic variants in a single gene cause neurodevelopmental disorder, Mayo study finds

By Susan Murphy Susan Murphy (@susanmurphy)

Rochester, Minn. — Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with […]

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Tags: #neurological diseases, Dr. Margot Cousin, genomics


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