Cancer
August 1, 2023
2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance
By Susan Murphy 
Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]
Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer
July 24, 2023
CAR-T cell therapy restores hope for leukemia patient
Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says Stahlecker. “We had bought land […]
Tags: #CAR T-cell therapy, center for individualized medicine, Center for Regenerative Medicine
May 3, 2023
New podcast: ‘Individualized Cancer Vaccines’
May 3, Episode 6: ‘Individualized Cancer Vaccines’ Some vaccines prevent cancer, while other vaccines treat cancer. In this episode, Cathy Wurzer, a broadcast journalist from Minnesota Public Radio, talks with two noted experts in immunology. Listen as they discuss the differences between the two vaccines, the excitement and challenges in the precision oncology world on […]
Tags: cancer vaccines, center for individualized medicine, clinical trials, immunotherapy, mayo clinic
April 13, 2023
Targeted immunotherapy helps Florida woman beat Lynch syndrome-driven colon cancer
By Susan Murphy
By Nicole Brudos Ferrara Cancer has always been a part of 44-year-old Katie Cunningham’s life. “We have an extensive family history of colon cancer on my dad’s side. We have a document going back to the 1800s,” says Katie. Katie and her family members have Lynch syndrome, an inherited condition that increases the risk of colon […]
Tags: center for individualized medicine, gene sequencing, personalized medicine
January 16, 2023
Mayo Clinic researchers link ovarian cancer to bacteria colonization in microbiome
By Susan Murphy
ROCHESTER, Minn. — A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic’s Center for Individualized Medicine. The discovery, published in Scientific Reports, strengthens evidence that the bacterial component of the microbiome — a community of microorganisms that also consists […]
Tags: center for individualized medicine, Dr. Abigail Asangba, Dr. Marina Walther-Antonio, genomics, ovarian cancer
January 10, 2023
Accelerating microbiome research in endometrial cancer
By Susan Murphy
By Alumni Magazine Marina Walther-Antonio, Ph.D., Departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, is a pioneer in studying the role of the microbiome in women’s health. Dr. Walther-Antonio is also Dean of Diversity, Equity and Inclusion in the Mayo Clinic Graduate School of Biomedical Science and an assistant professor in the Mayo Clinic College […]
Tags: center for individualized medicine, Dr. Marina Walther-Antonio, Endometrial cancer, genomic medicine
December 28, 2022
3 impactful Mayo Clinic cancer research studies of 2022
By Susan Murphy
In 2022, Mayo Clinic physicians and scientists interrogated the genome, exome, proteome, epigenome, exposome, transcriptome and more with remarkable depth to shed new light on the hidden biological signatures of cancer. Using artificial intelligence and a wealth of multi-omics data, the pioneering teams of researchers worked side by side to pave a path for potential […]
Tags: center for individualized medicine, Genetics, genomic medicine, personalized medicine
December 23, 2022
10 significant Mayo Clinic Center for Individualized Medicine Studies of 2022
By Susan Murphy
In 2022, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]
Tags: center for individualized medicine, gene sequencing, genomic medicine, individualized medicine, medical research
October 25, 2022
By Susan Murphy
ROCHESTER, Minn. – The next frontier in individualized medicine is here. Mayo Clinic’s 11th annual Individualizing Medicine Conference on Nov. 2–3 will focus on “Exploring the Exposome” — the cumulative measure of environmental influences and associated biological responses throughout the life span of a person, and how those exposures relate to health and disease. “We’ve […]
October 11, 2022
Sangre Por Salud Biobank helps fill need for diversity in genetics research
By Susan Murphy
By Gerri Kelly From Alzheimer’s disease and asthma to diabetes and a chemotherapy drug, researchers at Mayo Clinic are tapping the Sangre Por Salud (Spanish for “Blood for Health”) Biobank in Arizona, a rich source of biospecimens that expands diversity in medical research. The Sangre Por Salud Biobank was created in 2013 to expand precision […]
Tags: genomics