Cancer

January 16, 2023

Mayo Clinic researchers link ovarian cancer to bacteria colonization in microbiome 

By Susan Murphy Susan Murphy (@susanmurphy)

ROCHESTER, Minn. — A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic’s Center for Individualized Medicine. The discovery, published in Scientific Reports, strengthens evidence that the bacterial component of the microbiome — a community of microorganisms that also consists […]

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Tags: center for individualized medicine, Dr. Abigail Asangba, Dr. Marina Walther-Antonio, genomics, ovarian cancer


January 10, 2023

Accelerating microbiome research in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Alumni Magazine Marina Walther-Antonio, Ph.D., Departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, is a pioneer in studying the role of the microbiome in women’s health. Dr. Walther-Antonio is also Dean of Diversity, Equity and Inclusion in the Mayo Clinic Graduate School of Biomedical Science and an assistant professor in the Mayo Clinic College […]

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Tags: center for individualized medicine, Dr. Marina Walther-Antonio, Endometrial cancer, genomic medicine


December 28, 2022

3 impactful Mayo Clinic cancer research studies of 2022

By Susan Murphy Susan Murphy (@susanmurphy)

In 2022, Mayo Clinic physicians and scientists interrogated the genome, exome, proteome, epigenome, exposome, transcriptome and more with remarkable depth to shed new light on the hidden biological signatures of cancer. Using artificial intelligence and a wealth of multi-omics data, the pioneering teams of researchers worked side by side to pave a path for potential […]

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Tags: center for individualized medicine, Genetics, genomic medicine, personalized medicine


December 23, 2022

10 significant Mayo Clinic Center for Individualized Medicine Studies of 2022

By Susan Murphy Susan Murphy (@susanmurphy)

In 2022, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]

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Tags: center for individualized medicine, gene sequencing, genomic medicine, individualized medicine, medical research


October 25, 2022

Trailblazing scientists discuss advances in exposome research, precision nutrition at Mayo Clinic’s Individualizing Medicine Conference   

By Susan Murphy Susan Murphy (@susanmurphy)

ROCHESTER, Minn. – The next frontier in individualized medicine is here. Mayo Clinic’s 11th annual Individualizing Medicine Conference on Nov. 2–3 will focus on “Exploring the Exposome” — the cumulative measure of environmental influences and associated biological responses throughout the life span of a person, and how those exposures relate to health and disease.    “We’ve […]

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October 11, 2022

Sangre Por Salud Biobank helps fill need for diversity in genetics research

By Susan Murphy Susan Murphy (@susanmurphy)

By Gerri Kelly From Alzheimer’s disease and asthma to diabetes and a chemotherapy drug, researchers at Mayo Clinic are tapping the Sangre Por Salud (Spanish for “Blood for Health”) Biobank in Arizona, a rich source of biospecimens that expands diversity in medical research. The Sangre Por Salud Biobank was created in 2013 to expand precision […]

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Tags: genomics


October 10, 2022

Researchers investigate precision nutrition to improve health, prevent diseases 

By Susan Murphy Susan Murphy (@susanmurphy)

Could prescribing specific nutrients, grains, fruits and vegetables tailored to a person’s DNA and other biological characteristics help improve their health? Precision nutrition is taking center stage at Mayo Clinic’s upcoming Individualizing Medicine Conference on Nov. 2-3, 2022, in Rochester, Minnesota, where some of the world’s top experts will share their knowledge of the potential […]

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Tags: center for individualized medicine, Genetics, genomic medicine, genomics, medical research, precision nutrition


September 29, 2022

Addressing the challenges of chimeric antigen receptor-T cell therapy

By Susan Murphy Susan Murphy (@susanmurphy)

Article by Marla Broadfoot Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient’s T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has successfully sent patients with advanced disease into remission, it is far from perfect. CAR-T cell […]

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Tags: #CAR T-cell therapy, center for individualized medicine, immunotherapy


September 22, 2022

Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research


September 15, 2022

Designing Personalized Vaccines to Combat Cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers are working to develop personalized therapeutic cancer vaccines that can potentially target each person’s distinctive tumor characteristics. The new approach, built on advances in genomic research and data analytics, holds transformative potential to boost the power of the immune system to identify and attack cancer cells. 

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Tags: Cancer Research, cancer vaccine, center for individualized medicine, Genetics, medical research, neoantigen, personalized medicine


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