Cancer

January 1, 2024

Mayo Clinic patients find hope in individualized medicine in 2023

By Susan Murphy Susan Murphy (@susanmurphy)

In a remarkable year of medical advancements and discoveries, the Mayo Clinic Center for Individualized Medicine has touched the lives of many patients. From groundbreaking treatments to life-changing diagnoses, the stories of these patients highlight the profound impact of Mayo Clinic’s innovative and personalized approaches. Here is a look back at some notable patient journeys from […]

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October 31, 2023

Mayo Clinic’s DNA study reveals BRCA1 mutations in 3 sisters, prompts life-changing decisions

By Susan Murphy Susan Murphy (@susanmurphy)

Sisters often share certain genetic traits, such as hair color and facial features. But for three sisters from Minnesota, they discovered a much deeper connection — a shared genetic mutation known to dramatically increase their risk for breast and ovarian cancer. Their BRCA1 variants came to light through a Mayo Clinic Center for Individualized Medicine […]

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Tags: Dr. Konstantinos Lazaridis


August 1, 2023

2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance

By Susan Murphy Susan Murphy (@susanmurphy)

Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]

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Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer


July 24, 2023

CAR-T cell therapy restores hope for leukemia patient

By Susan Buckles Susan Buckles (@susanbuckles)

Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says Stahlecker. “We had bought land […]

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Tags: #CAR T-cell therapy, center for individualized medicine, Center for Regenerative Medicine


May 3, 2023

New podcast: ‘Individualized Cancer Vaccines’

By Colette Gallagher Colette Gallagher (@colettegallagher)

May 3, Episode 6: ‘Individualized Cancer Vaccines’  Some vaccines prevent cancer, while other vaccines treat cancer. In this episode, Cathy Wurzer, a broadcast journalist from Minnesota Public Radio, talks with two noted experts in immunology. Listen as they discuss the differences between the two vaccines, the excitement and challenges in the precision oncology world on […]

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Tags: cancer vaccines, center for individualized medicine, clinical trials, immunotherapy, mayo clinic


April 13, 2023

Targeted immunotherapy helps Florida woman beat Lynch syndrome-driven colon cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Nicole Brudos Ferrara Cancer has always been a part of 44-year-old Katie Cunningham’s life. “We have an extensive family history of colon cancer on my dad’s side. We have a document going back to the 1800s,” says Katie. Katie and her family members have Lynch syndrome, an inherited condition that increases the risk of colon […]

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Tags: center for individualized medicine, gene sequencing, personalized medicine


January 16, 2023

Mayo Clinic researchers link ovarian cancer to bacteria colonization in microbiome

By Susan Murphy Susan Murphy (@susanmurphy)

ROCHESTER, Minn. — A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic’s Center for Individualized Medicine. The discovery, published in Scientific Reports, strengthens evidence that the bacterial component of the microbiome — a community of microorganisms that also consists […]

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Tags: center for individualized medicine, Dr. Abigail Asangba, Dr. Marina Walther-Antonio, genomics, ovarian cancer


January 10, 2023

Accelerating microbiome research in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Alumni Magazine Marina Walther-Antonio, Ph.D., Departments of Surgery and Obstetrics and Gynecology at Mayo Clinic in Rochester, is a pioneer in studying the role of the microbiome in women’s health. Dr. Walther-Antonio is also Dean of Diversity, Equity and Inclusion in the Mayo Clinic Graduate School of Biomedical Science and an assistant professor in the Mayo Clinic College […]

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Tags: center for individualized medicine, Dr. Marina Walther-Antonio, Endometrial cancer, genomic medicine


December 28, 2022

3 impactful Mayo Clinic cancer research studies of 2022

By Susan Murphy Susan Murphy (@susanmurphy)

In 2022, Mayo Clinic physicians and scientists interrogated the genome, exome, proteome, epigenome, exposome, transcriptome and more with remarkable depth to shed new light on the hidden biological signatures of cancer. Using artificial intelligence and a wealth of multi-omics data, the pioneering teams of researchers worked side by side to pave a path for potential […]

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Tags: center for individualized medicine, Genetics, genomic medicine, personalized medicine


December 23, 2022

10 significant Mayo Clinic Center for Individualized Medicine Studies of 2022

By Susan Murphy Susan Murphy (@susanmurphy)

In 2022, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]

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Tags: center for individualized medicine, gene sequencing, genomic medicine, individualized medicine, medical research


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