Cancer
June 15, 2021
New Mayo study validates melanoma test to help some patients avoid surgical biopsy
By Susan Murphy 
More than 100,00 people in the U.S. are expected to be diagnosed with melanoma this year — double the number of cases compared to 30 years ago, according to the American Academy of Dermatology Association. “Melanoma accounts for only about 2% of skin cancers, but it causes a majority of skin cancer deaths,” says Alexander […]
Tags: #Dr. Alexander Meves, Melanoma
May 25, 2021
Gene fusion discovery in ultrarare tumor highlights potential therapeutic target
By Susan Murphy
A scientific investigation led by a team of researchers from Mayo Clinic’s Center for Individualized Medicine reveals that an ultrarare cancer called epithelioid trophoblastic tumor (ETT), which can develop in the uterus after conception, recurrently exhibits an abnormal fusion of two genes. This fusion creates an unusual protein that triggers aggressive cell growth — the […]
Tags: #Gavin Oliver, Dr. Eric Klee
May 4, 2021
Mayo Clinic Center for Individualized Medicine refreshes website
The Mayo Clinic Center for Individualized Medicine website was recently updated to reflect Mayo Clinic’s continued focus on integrating precision medicine into the practice to improve patient care. In the last decade, Mayo Clinic researchers, physicians, and staff in the Center have been collaborating closely in a comprehensive team science approach to push the boundaries […]
Tags: mayo clinic, Mayo Clinic Center for Individualized Medicine
April 26, 2021
Researchers develop new technique to study ‘microcancers’ and screen cancer-fighting drugs
By Susan Murphy
By University of Illinois Urbana-Champaign Three-dimensional microscale hanging drop arrays are useful in drug discovery, regenerative medicine, stem cell research, and biotechnology. A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers […]
April 22, 2021
Meet 5 Mayo scientists researching ‘beyond DNA’ to advance personalized medicine
By Susan Murphy
As the nation marks National DNA Day on Sunday, April 25 — a day that commemorates the discovery of DNA’s double helix in 1953 and the completion of the Human Genome Project in 2003 — Mayo Clinic physicians and researchers will continue to closely collaborate to push the boundaries of precision medicine in the areas […]
March 29, 2021
Mayo researchers use AI to reveal causes of complex diseases
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]
Tags: #algorithm, #Artificial Intelligence, cancer, colon cancer, colorectal cancer, multi-omics, rare disease
March 19, 2021
Lack of diversity in genomic databases may affect therapy selection for minority groups
Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White patients. As a […]
Tags: #Dr. Aaron Mansfield, #Dr. Mitesh Borad, #Dr. Yan Asmann, Dr. Alex Adjei, Dr. Leif Bergsagel, mayo clinic
August 28, 2020
2020 Gerstner Awards boost research in AI cancer algorithms, neurodegenerative diseases
By Susan Murphy
Veronique Belzil, Ph.D., assistant professor in Mayo Clinic’s Department of Neuroscience in Jacksonville, Fla., and Feichen Shen, Ph.D., assistant professor of Biomedical Informatics in Rochester, Minn., are this year’s recipients of the Gerstner Family Career Development Awards. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers who are early […]
Tags: #Artificial Intelligence, #Gerstner Family Career Development Award, ALS, Gerstner Family Foundation
August 12, 2020
Could population genetic screening improve public health?
Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]
Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research
June 16, 2020
Mayo Clinic, NASA team up to test AI algorithm on colorectal cancer
By Susan Murphy
Mayo is working with NASA to sequence the path of cancer — from what causes it to what drives it, and potentially how to prevent it. Mayo researchers and NASA Frontier Development Lab data scientists are embarking on a research sprint this month to optimize an artificial intelligence (AI) algorithm for colorectal cancer and possibly […]