Cancer
April 2, 2019
Purna Kashyap, M.B.B.S. – testing the bugs within to maintain health, detect and treat disease
By Sharon Rosen 
The use of microbiome testing – which analyzes the trillions of bacteria in and on the body – is on the move. It’s going from the research lab into the clinic to help guide patient care. DNA testing technologies have revolutionized researchers’ ability to identify individual bacterial strains driving disease. Now genomic testing is helping […]
Tags: #blood sugar levels, #Center for Individualized Medicine Microbiome Program, #diabetes, #digestive health, #glucose levels, #inflammatory bowel disease, #obesity, #personalized diet, c. difficile, center for individualized medicine, colorectal cancer, Dr. Purna Kashyap
March 12, 2019
Colon cancer awareness: A new era in cancer detection and treatment
March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]
Tags: #Hereditary colorectal cancer, Dr. Niloy "Jewel" Samadder, hereditary cancer, lynch syndrome, Mayo Clinic Arizona campus, Mayo Clinic Center for Individualized Medicine
March 5, 2019
By Sharon Rosen
Space-age technologies, DNA sequencing and artificial intelligence – all tools for discovery that Nicholas Chia, Ph.D. and his team are using to push the envelope and improve care for complex diseases like colorectal cancer. They’re collaborating with scientists from NASA to uncover how the microbiome – the trillions of microbes in and on the body […]
Tags: #ecology, #genomic testing, #Kidney stones, #microbial ecology, #systems biology, bacteria, colorectal cancer, DNA Sequencing, Dr. Nicholas Chia, gut bacteria, mayo clinic, Mayo Clinic Center for Individualized Medicine
January 28, 2019
Triumph out of tragedy: A home screening test for cervical cancer
January is Cervical Health Awareness Month, a time to reflect on personalized approaches to preventing or treating cervical cancer. Harrowing stories of rampant sexual violence and high instances of cervical cancer in the Democratic Republic of Congo spurred Marina Walther-Antonio, Ph.D. to action. The emotional stories of survival and death triggered her desire to discover […]
Tags: #Cervical cancer, #Cervical cancer screening, #Democratic Republic of Congo, #HPV, #HPV screening, center for individualized medicine, Dr. Marina Walther-Antonio
January 3, 2019
Mayo Clinic discovers biological markers that could guide treatment for prostate cancer
Prostate cancer is the most common form of cancer in American men, other than skin cancer.* Statistics from the American Cancer Society show approximately 1 in 9 American men will be diagnosed with prostate cancer at some time in their lives. Mayo Clinic Center for Individualized Medicine-sponsored research released today may help families facing difficult […]
Tags: George Vasmatzis Ph.D., Gleason pattern 3 prostate cancer, John Cheville M.D., Mayo Clinic Center for Individualized Medicine, Mayo Clinic Center for Individualized Medicine Biomarker Discovery Program, Prostate Cancer
December 3, 2018
Meet Sanjay Bagaria, M.D.: new CIM associate director in Florida
By Sharon Rosen
Hindsight is 20/20.That saying rings true for surgical oncologist Sanjay Bagaria, M.D. As a premedical student at University of Michigan, he chose to major in Japanese studies, mastering thousands of characters and a new grammar structure to read the Japanese literature he loved. Looking back, that experience gave him the tools to view not only […]
Tags: #Associate director Center for Individualized Medicine, #basal-like breast cancer, #Dr. Sanjay Bagaria, #hyperthermic intraperitoneal chemotherapy (HIPEC) surgery, #Mayo Clinic Campus in Florida, #surgical oncologist, biomarkers, center for individualized medicine, mayo clinic, medical research
November 26, 2018
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]
Tags: #Dr. Aaron Mansfield, #mesothelioma, Cancer Research, Dr. George Vasmatzis, Mayo Clinic Center for Individualized Medicine
November 19, 2018
Gene therapy: potential and pitfalls
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food and Drug Administration for clinical […]
Tags: #Brittle bone disease, #CAR T-cell therapy, #Dr. David Deyle, #gene therapy, Dr. Saad Kenderian, Mayo Clinic Center for Individualized Medicine, medical research
November 12, 2018
Novel data-driven approach for precision medicine
Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization […]
Tags: #Dr. Krishna Kalari, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Mayo Clinic Center for Individualized Medicine, personal genomics, pharmacogenomics
November 5, 2018
Pharmacogenomics: finding the right drug, dose for cancer therapy
By Sharon Rosen
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]
Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine