April 26, 2021

Researchers develop new technique to study ‘microcancers’ and screen cancer-fighting drugs

By Susan Murphy Susan Murphy (@susanmurphy)

By University of Illinois Urbana-Champaign Three-dimensional microscale hanging drop arrays are useful in drug discovery, regenerative medicine, stem cell research, and biotechnology. A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers […]

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April 22, 2021

Meet 5 Mayo scientists researching ‘beyond DNA’ to advance personalized medicine

By Susan Murphy Susan Murphy (@susanmurphy)

As the nation marks National DNA Day on Sunday, April 25 — a day that commemorates the discovery of DNA’s double helix in 1953 and the completion of the Human Genome Project in 2003 — Mayo Clinic physicians and researchers will continue to closely collaborate to push the boundaries of precision medicine in the areas […]

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March 29, 2021

Mayo researchers use AI to reveal causes of complex diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]

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Tags: #algorithm, #Artificial Intelligence, cancer, colon cancer, colorectal cancer, multi-omics, rare disease

March 19, 2021

Lack of diversity in genomic databases may affect therapy selection for minority groups

By Colette Gallagher Colette Gallagher (@colettegallagher)

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White patients. As a […]

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Tags: #Dr. Aaron Mansfield, #Dr. Mitesh Borad, #Dr. Yan Asmann, Dr. Alex Adjei, Dr. Leif Bergsagel, mayo clinic

August 28, 2020

2020 Gerstner Awards boost research in AI cancer algorithms, neurodegenerative diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Veronique Belzil, Ph.D., assistant professor in Mayo Clinic’s Department of Neuroscience in Jacksonville, Fla., and Feichen Shen, Ph.D., assistant professor of Biomedical Informatics in Rochester, Minn., are this year’s recipients of the Gerstner Family Career Development Awards. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers who are early […]

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Tags: #Artificial Intelligence, #Gerstner Family Career Development Award, ALS, Gerstner Family Foundation

August 12, 2020

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher (@colettegallagher)

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research

June 16, 2020

Mayo Clinic, NASA team up to test AI algorithm on colorectal cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo is working with NASA to sequence the path of cancer — from what causes it to what drives it, and potentially how to prevent it. Mayo researchers and NASA Frontier Development Lab data scientists are embarking on a research sprint this month to optimize an artificial intelligence (AI) algorithm for colorectal cancer and possibly […]

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Tags: #Artificial Intelligence, cancer, colorectal cancer

June 1, 2020

Seeing cancer, but not through a microscope

By Susan Murphy Susan Murphy (@susanmurphy)

By Marla Broadfoot, Ph.D. / Discovery’s Edge Toward the end of the 19th century, a French doctor named Ernest Besnier coined the term “biopsy,” combining the Greek bios (life) and opsis (a sight). In the decades since, clinicians have performed countless biopsies on suspected cancer patients, all to catch a glimpse of cells on the […]

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Tags: cancer, Cancer Research, Genetics, Research

May 11, 2020

AI enhances MRI images to identify molecular markers of brain cancer

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Five years ago Bradley Erickson, M.D., Ph.D. never would have imagined that an MRI would be able to identify the molecular characteristics of brain cancer. But because of the rapid advances in artificial intelligence (AI), that scenario isn’t science fiction. It’s an exciting medical reality for Dr. Erickson, a radiologist on Mayo Clinic’s campus in […]

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Tags: #Artificial Intelligence, cancer, gliomas

April 27, 2020

Noninvasive test may help some patients with melanoma avoid lymph node biopsy

By Jay Furst Jay Furst (@jayfurst)

A Mayo Clinic-led research team has developed a test for patients who have melanoma, the most serious form of skin cancer, that shows whether they’re at risk of the cancer spreading to other areas of the body. The research, described in the journal JCO Precision Oncology, could allow some patients at low risk of metastasis […]

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Tags: cancer, Melanoma, Research

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