Microbiome

July 20, 2022

2022 Gerstner Awardee to investigate gut microbiome link to chemotherapy-induced nausea

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Singh is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract. 

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Tags: center for individualized medicine, genomic medicine, genomics


July 6, 2022

Do environmental exposures contribute to human diseases? 

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers put the exposome under the microscope to understand links between lifelong exposures and diseases.

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Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, exposome, gene sequencing, Genetics, genomics


May 19, 2022

Study indicates gut microbiome, host gene affect gastrointestinal disorders

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research, personalized medicine


April 25, 2022

On National DNA Day, Mayo Clinic researchers put genomics into action to advance individualized medicine

By Susan Murphy Susan Murphy (@susanmurphy)

National DNA Day on Monday, April 25, marks the discovery of DNA’s double helix in 1953 and the Human Genome Project’s completion in 2003.  For the first time, a team of scientists led by the National Institutes of Health has finished sequencing an entire human genome — all of the roughly 3 billion bases of […]

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Tags: Dr. Konstantinos Lazaridis, Genetic Sequencing, Genetic Testing, Genetics, genome, Human Genome Project


December 28, 2021

10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021

By Susan Murphy Susan Murphy (@susanmurphy)

It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses. 

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics


September 14, 2021

Mayo researchers link gut microbiome to rheumatoid arthritis prognosis

By Susan Murphy Susan Murphy (@susanmurphy)

A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]

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Tags: #Dr. Jaeyun Sung, Dr. John Davis, genomics, microbiome, Rheumatoid Arthritis


August 9, 2021

Mayo Clinic analysis shows how disease, diet, and genomics interact with gut virome

By Colette Gallagher Colette Gallagher (@colettegallagher)

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Tags: center for individualized medicine, Dr. Purna Kashyap, Genetics, mayo clinic, medical research, microbiome, personalized medicine


July 21, 2021

Researchers review how sex steroids change gut, vaginal microbiome

By Colette Gallagher Colette Gallagher (@colettegallagher)

It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal microbiomes influence women’s health outcomes […]

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Tags: Dr. Marina Walther-Antonio, Gut Microbiome, Mayo Clinic Center for Individualized Medicine, vaginal microbiome


June 24, 2021

Mayo researchers develop algorithm to predict rheumatoid arthritis disease activity

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in a patient. The algorithm analyzes biochemical metabolites ― the product of the body’s metabolism ― in blood. “Having fast, reliable and scalable measures for predicting the clinical course […]

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Tags: #algorithm, genomics, Precision Medicine, Rheumatoid Arthritis


April 22, 2021

Meet 5 Mayo scientists researching ‘beyond DNA’ to advance personalized medicine

By Susan Murphy Susan Murphy (@susanmurphy)

As the nation marks National DNA Day on Sunday, April 25 — a day that commemorates the discovery of DNA’s double helix in 1953 and the completion of the Human Genome Project in 2003 — Mayo Clinic physicians and researchers will continue to closely collaborate to push the boundaries of precision medicine in the areas […]

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