Precision Medicine
August 10, 2023
Mayo Clinic ‘mini-brain’ study reveals possible key link to autism spectrum disorder
By Susan Murphy 
Using human “mini-brain” models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions. The specific cells are known as excitatory cortical neurons. The new study […]
Tags: Alexej Abyzov, autism, Biomedical research, center for individualized medicine, genomic medicine, organoids
August 1, 2023
2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance
By Susan Murphy
Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]
Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer
August 1, 2023
2023 Gerstner Awardee to investigate individualized treatment strategy for follicular lymphoma
By Susan Murphy
Patrizia Mondello, M.D., Ph.D., M.Sc., a physician-scientist in Mayo Clinic’s Department of Hematology, is a recipient of the annual 2023 Gerstner Family Career Development Award from the Mayo Clinic Center for Individualized Medicine. The competitive awards advance innovative research to predict, prevent, treat, and cure diseases using individualized medicine. Inspired by a 20-year-old woman named […]
Tags: Biomedical research, center for individualized medicine, genomic medicine
July 24, 2023
CAR-T cell therapy restores hope for leukemia patient
Jon Stahlecker had exhausted all treatment options and lost hope of surviving chronic lymphocytic leukemia (CLL) before the Mayo Clinic offered him chimeric antigen receptor-T cell therapy (CAR-T cell therapy) in a clinical trial. “We got all our affairs in order. I was trying to see as many people and relatives as I could,” says Stahlecker. “We had bought land […]
Tags: #CAR T-cell therapy, center for individualized medicine, Center for Regenerative Medicine
July 21, 2023
In a pilot study of 165 people, Mayo Clinic researchers looked at the effectiveness of two different approaches to weight loss: a standard lifestyle intervention and individualized therapy. The standard lifestyle intervention included a reduced diet, exercise and behavior therapy. The individualized approach was based on phenotypes and included different interventions depending on the person’s […]
Tags: Biomedical research, center for individualized medicine, Dr. Andres Acosta, genomic medicine, mayo clinic
July 19, 2023
By Susan Murphy
Mayo Clinic scientists are building an expansive library of DNA blueprints of disease-causing bacterial species. The unique collection of genomic sequences is serving as a reference database to help doctors provide rapid and precise diagnoses and pinpoint targeted treatments to potentially improve patient outcomes.
Tags: #bacterial infections, Biomedical research, center for individualized medicine, DNA Testing, genomics
July 18, 2023
New Podcast: ‘Xenotransplantation and Regenerative Therapeutics’
July 12, Episode 11: ‘Xenotransplantation and Regenerative Therapeutics What if we could replace diseased or damaged organs and other body parts with new lab-created versions? How might transplanting tissue from other species help the critical shortage of human transplant organs? Tune in as Cathy Wurzer, a broadcast journalist from Minnesota Public Radio interviews two noted […]
Tags: center for individualized medicine, genomic medicine, mayo clinic
July 3, 2023
Mayo Clinic discovery leads to diagnoses of 9 people with rare form of muscular dystrophy
By Susan Murphy
Nine people around the world who have been living with unexplained, muscular dystrophy-like symptoms may now have an answer for what is causing the progressive muscle weakness in their body’s mid-section, arms and legs. In a new discovery, a collaborative team of scientists led by researchers at Mayo Clinic’s Center for Individualized Medicine has pinpointed […]
Tags: Biomedical research, center for individualized medicine, Dr. Eric Klee, genomics
June 28, 2023
New podcast: ‘Wearables & Digital Health’
June 28, Episode 10: ‘Wearables & Digital Health’ Wearable technology has come a long way from being a novelty. These wearables are now being used to help monitor patients to forestall problems. They can help people take a more active role in their health. Plus, the trove of data they collect can help medical researchers. […]
Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic
June 26, 2023
Mayo Clinic uses genomic testing broadly for rare diseases, improves patient care
A Mayo Clinic study published in Journal of Translational Medicine evaluated the use of genomic testing broadly for rare diseases. With the increased use of genomic testing such as multi-gene panels, exome sequencing and genome sequencing in the past decade, there is a greater opportunity to better diagnose and treat patients with rare diseases. According […]
Tags: Biomedical research, center for individualized medicine, Genetic Testing, individualized medicine, mayo clinic