Precision Medicine

March 17, 2022

Mayo Clinic study reports genomic data disparities among racial groups

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas. “We found lower quality genomic sequencing data in self-reported Black patients and patients of African ancestry,” says Yan Asmann., Ph.D., a Mayo Clinic bioinformatician and senior […]

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Tags: Cancer Research, center for individualized medicine, DNA Testing, mayo clinic


March 16, 2022

Mayo Clinic researchers use AI to predict antidepressant outcomes in youth

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine


March 11, 2022

Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows 

By Susan Murphy Susan Murphy (@susanmurphy)

A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections.  In response, a team of researchers from Mayo Clinic’s Center for Individualized Medicine has developed […]

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Tags: antibiotic-resistant, bacteria, center for individualized medicine, Genetics, genomics, infectious disease, personalized medicine


February 28, 2022

Young girl with rare disease gets life-changing diagnosis and targeted therapy at Mayo Clinic

By Susan Murphy Susan Murphy (@susanmurphy)

Araeya Sell, 13, has spent much of her childhood visiting her health care team and in the hospital. She has endured countless blood draws, scans, procedures and a surgery ― all in the search for answers to her complex symptoms.  After an exhaustive, nearly seven-year diagnostic odyssey, the Sells turned to Mayo Clinic.

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Tags: center for individualized medicine, Dr. Konstantinos Lazaridis, Dr. Pinto e Vairo, Genetics, genomics


February 16, 2022

Mass spectrometry-based assay detects viral antigens directly from clinical specimens

By Susan Murphy Susan Murphy (@susanmurphy)

By Mayo Clinic Laboratories In a newly published study, a team from Mayo Clinic’s Advanced Diagnostics Laboratory has developed a mass spectrometry-based assay that’s able to detect COVID-19 (SARS-CoV-2) pathogens from human proteins with, remarkably, 98% sensitivity and 100% specificity. This is the first assay of its kind that can detect viral antigens “directly from clinical specimens” such […]

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Tags: center for individualized medicine, covid-19, Dr. Akhilesh Pandey, Mayo Clinic Advanced Diagnostic Laboratory


February 9, 2022

Mayo Clinic develops automated system to accelerate diagnoses for patients with rare diseases

By Susan Murphy Susan Murphy (@susanmurphy)

A team of genomics experts within Mayo Clinic’s Center for Individualized Medicine has developed an automated system for tracking new scientific knowledge from around the world of pathogenic genetic variants and applying it to Mayo Clinic patients with rare and undiagnosed diseases.

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Tags: center for individualized medicine, Dr. Alejandro Ferrer, Dr. Eric Klee


February 4, 2022

History of infectious disease outbreaks and vaccines timeline

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have developed a digital historical timeline of infectious disease outbreaks and vaccines. The timeline spans the development of a smallpox vaccine in 1796 to the COVID-19 pandemic.

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February 3, 2022

Lung cancer: It is about more than smoking

By Susan Murphy Susan Murphy (@susanmurphy)

By Sharon Theimer World Cancer Day is February 4 and that makes this the ideal time to talk about lung cancer and smoking. Internationally, lung cancer is the most common cause of cancer deaths and the World Health Organization estimates that 90% of cases could be prevented by eliminating tobacco use. People who smoke are at the greatest risk. Smokeless tobacco is also associated […]

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Tags: #Dr. Aaron Mansfield, #mesothelioma, Lung Cancer


January 27, 2022

Navigating Life’s Journey with the Right Topographical Map

By Susan Murphy Susan Murphy (@susanmurphy)

Combining genetic sequencing, life-style modification, and personalized drug therapy will transform health care. John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article. While still prevalent, the one-size-fits-all health care is slowly giving way to a more precise, personalized approach that takes into […]

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January 20, 2022

NIH announces awards for precision nutrition study

By Colette Gallagher Colette Gallagher (@colettegallagher)

The Nutrition for Precision Health study leverages NIH’s All of Us Research Program’s large, diverse data platform. The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country, including Mayo Clinic, for a new study that will develop algorithms to predict individual […]

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Tags: All of Us Research Program, Biobank, center for individualized medicine, mayo clinic, National Institutes of Health, Nutrition for Precision Health


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