Research

August 12, 2020

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research


August 4, 2020

COVID-19 “Live” Virus Research In a Specialized Lab

By Sara Tiner Sara Tiner

To solve the challenges presented by COVID-19, it’s important to look to the past. History shows that collaboration is the way forward when uncovering secrets of an emerging virus. It is vital for many reasons, a key one being safety. Only a few labs can safely handle a “live,” meaning infectious, sample. No one knows […]

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Tags: covid-19


July 6, 2020

Mayo Clinic expert answers COVID-19 questions — from school safety to vaccines to new flu virus concerns

By Susan Murphy Susan Murphy

By Dana Sparks As COVID-19 continues to cause concern and consume people’s lives across the globe, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, offers some insights and answers on the status of the pandemic. Scientists around the world are working feverishly on vaccines, what’s the status of vaccine research? The U.S. Food […]

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Tags: covid-19


July 1, 2020

Mayo researchers earn NIH award to study use of genetic risk scores for heart disease in diverse populations

By Susan Murphy Susan Murphy

In recognition of their high impact work of advancing the field of genetic risk profiling for disease risk stratification, the National Institutes of Health (NIH) has awarded Mayo Clinic researchers Iftikhar Kullo, M.D. and Richard Sharp Ph.D. part of $75 million in funding over five years to improve the role of genomics in assessing and […]

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Tags: Bioethics, Cardiovascular Disease, Genetics


June 29, 2020

Mayo Clinic COVID-19 modeling for patients, communities

By Susan Murphy Susan Murphy

By Elizabeth Zimmermann| Discovery’s Edge Building predictions based on a set of variables, an effort called modeling, has gotten a lot of airtime during the COVID-19 pandemic. Understanding both the virus and the disease, including how it spreads and its impacts on population health, guides advice to the public on how to stay safe. At […]

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Tags: covid-19, Research


June 23, 2020

Controversial CRISPR case in China raises stakes for how genetic research is conducted

By Jay Furst Jay Furst

Mayo Clinic colleagues take a close look at what went wrong with the process in China and how it challenged the implicit “social contract” between science and society In November 2018, a Chinese biophysicist used a gene-editing technique known by the acronym CRISPR to edit human embryos for reproductive purposes, and he announced the birth […]

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Tags: CRISPR, genomics, Research


June 8, 2020

Unanswered Questions Drive Convalescent Plasma Research

By Susan Murphy Susan Murphy

By Sara Tiner On Saturday, March 14, in southwest Wisconsin, a woman was working in her yard, raking and clearing the first spring weeds. She coughed a bit during the day, and felt some achiness in her lower back, some fatigue. It was in the high 30s that day, but she was warm when she […]

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Tags: covid-19, Research


May 11, 2020

AI enhances MRI images to identify molecular markers of brain cancer

By Sharon Rosen Sharon Rosen

Five years ago Bradley Erickson, M.D., Ph.D. never would have imagined that an MRI would be able to identify the molecular characteristics of brain cancer. But because of the rapid advances in artificial intelligence (AI), that scenario isn’t science fiction. It’s an exciting medical reality for Dr. Erickson, a radiologist on Mayo Clinic’s campus in […]

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Tags: artificial intelligence, cancer, gliomas


April 27, 2020

Noninvasive test may help some patients with melanoma avoid lymph node biopsy

By Jay Furst Jay Furst

A Mayo Clinic-led research team has developed a test for patients who have melanoma, the most serious form of skin cancer, that shows whether they’re at risk of the cancer spreading to other areas of the body. The research, described in the journal JCO Precision Oncology, could allow some patients at low risk of metastasis […]

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Tags: cancer, Melanoma, Research


April 25, 2020

Why do diseases such as COVID-19 and cancer hit some people harder than others?

By Susan Murphy Susan Murphy

As the nation marks DNA Day on April 25 — commemorating the discovery of DNA’s double helix in 1953 and the completion of the Human Genome Project in 2003 — Mayo Clinic researcher Nicholas Chia, Ph.D., continues to search for answers to the question of why some people are more susceptible to getting a severe […]

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Tags: cancer genomics, DNA, genomics, microbiome, rare disease


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