Research

May 4, 2021 · Leave a Comment

Mayo Clinic Center for Individualized Medicine refreshes website

By Colette Gallagher Colette Gallagher (@colettegallagher)

The Mayo Clinic  Center for Individualized Medicine website was recently updated to reflect Mayo Clinic’s continued focus on integrating precision medicine into the practice to improve patient care. In the last decade, Mayo Clinic researchers, physicians, and staff in the Center have been collaborating closely in a comprehensive team science approach to push the boundaries […]

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Tags: mayo clinic, Mayo Clinic Center for Individualized Medicine


April 26, 2021 · Leave a Comment

Researchers develop new technique to study ‘microcancers’ and screen cancer-fighting drugs

By Susan Murphy Susan Murphy (@susanmurphy)

By University of Illinois Urbana-Champaign Three-dimensional microscale hanging drop arrays are useful in drug discovery, regenerative medicine, stem cell research, and biotechnology. A team from the University of Illinois Urbana-Champaign’s Grainger College of Engineering and Mayo Clinic have developed a new technique for creating “microcancer” cell cultures. It allows researchers to form hundreds of microcancers […]

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April 22, 2021

Meet 5 Mayo scientists researching ‘beyond DNA’ to advance personalized medicine

By Susan Murphy Susan Murphy (@susanmurphy)

As the nation marks National DNA Day on Sunday, April 25 — a day that commemorates the discovery of DNA’s double helix in 1953 and the completion of the Human Genome Project in 2003 — Mayo Clinic physicians and researchers will continue to closely collaborate to push the boundaries of precision medicine in the areas […]

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March 29, 2021

Mayo researchers use AI to reveal causes of complex diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]

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Tags: #algorithm, artificial intelligence, cancer, colon cancer, colorectal cancer, multi-omics, rare disease


March 19, 2021 · Leave a Comment

Lack of diversity in genomic databases may affect therapy selection for minority groups

By Colette Gallagher Colette Gallagher (@colettegallagher)

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White patients. As a […]

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Tags: #Dr. Aaron Mansfield, #Dr. Mitesh Borad, #Dr. Yan Asmann, Dr. Alex Adjei, Dr. Leif Bergsagel, mayo clinic


December 8, 2020 · Leave a Comment

Mayo study explores benefits of genetic testing for healthy people

By Colette Gallagher Colette Gallagher (@colettegallagher)

More than 1 in 10 people who had predictive genomic testing ― testing that looks for genetic mutations in otherwise healthy people ― learned that they had a hereditary risk for a health condition and may benefit from preventive care, according to a recent study published in Mayo Clinic Proceedings. This study is the first […]

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Tags: #predictive genomics, Genetic Testing, Jennifer L. Anderson, mayo clinic, Mayo Clinic Center for Individualized Medicine, Mayo Clinic Proceedings


September 9, 2020

Mayo Clinic research advances diagnostics to lead COVID-19 pandemic response

By Susan Murphy Susan Murphy (@susanmurphy)

When COVID-19 spread across the U.S. in early March, Mayo Clinic’s Advanced Diagnostic Laboratory (ADL) urgently responded. Lab spaces were transitioned, staff reassigned and funding approvals were fast-tracked. Its goals were to accelerate research, development, translation and implementation of novel tests in order to discover life-saving treatments and diagnostics. “ADL houses a lab structure for […]

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Tags: covid-19, diagnostic tests, Discovery Square


August 28, 2020

2020 Gerstner Awards boost research in AI cancer algorithms, neurodegenerative diseases

By Susan Murphy Susan Murphy (@susanmurphy)

Veronique Belzil, Ph.D., assistant professor in Mayo Clinic’s Department of Neuroscience in Jacksonville, Fla., and Feichen Shen, Ph.D., assistant professor of Biomedical Informatics in Rochester, Minn., are this year’s recipients of the Gerstner Family Career Development Awards. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers who are early […]

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Tags: #Gerstner Family Career Development Award, ALS, artificial intelligence, Gerstner Family Foundation


August 12, 2020 · Leave a Comment

Could population genetic screening improve public health?

By Colette Gallagher Colette Gallagher (@colettegallagher)

Hereditary BRCA-related breast and ovarian cancer, Lynch syndrome and familial hypercholesterolemia are estimated to be relatively prevalent in the general population but poorly found using traditional risk screening. In a typical medical practice, genetic testing for these conditions is based on personal or family history, ethnic background or other demographic characteristics, that may not always […]

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Tags: #Familial hypercholesterolemia, breast cancer, Dr. Matthew Ferber, lynch syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, ovarian cancer, population health genomics, Research


August 4, 2020 · Leave a Comment

COVID-19 “Live” Virus Research In a Specialized Lab

By Sara Tiner Sara Tiner (@saratiner)

To solve the challenges presented by COVID-19, it’s important to look to the past. History shows that collaboration is the way forward when uncovering secrets of an emerging virus. It is vital for many reasons, a key one being safety. Only a few labs can safely handle a “live,” meaning infectious, sample. No one knows […]

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Tags: covid-19


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