Research
April 2, 2019
Purna Kashyap, M.B.B.S. – testing the bugs within to maintain health, detect and treat disease
By Sharon Rosen 
The use of microbiome testing – which analyzes the trillions of bacteria in and on the body – is on the move. It’s going from the research lab into the clinic to help guide patient care. DNA testing technologies have revolutionized researchers’ ability to identify individual bacterial strains driving disease. Now genomic testing is helping […]
Tags: #blood sugar levels, #Center for Individualized Medicine Microbiome Program, #diabetes, #digestive health, #glucose levels, #inflammatory bowel disease, #obesity, #personalized diet, c. difficile, center for individualized medicine, colorectal cancer, Dr. Purna Kashyap
March 12, 2019
Colon cancer awareness: A new era in cancer detection and treatment
March is Colorectal Cancer Awareness Month, a time to focus on one of the most common and preventable forms of cancer. Mayo Clinic is applying a new genomic lens to colorectal and other cancers to identify which are the types that run in families. The answer to that could open new treatment options and also […]
Tags: #Hereditary colorectal cancer, Dr. Niloy "Jewel" Samadder, hereditary cancer, lynch syndrome, Mayo Clinic Arizona campus, Mayo Clinic Center for Individualized Medicine
March 5, 2019
By Sharon Rosen
Space-age technologies, DNA sequencing and artificial intelligence – all tools for discovery that Nicholas Chia, Ph.D. and his team are using to push the envelope and improve care for complex diseases like colorectal cancer. They’re collaborating with scientists from NASA to uncover how the microbiome – the trillions of microbes in and on the body […]
Tags: #ecology, #genomic testing, #Kidney stones, #microbial ecology, #systems biology, bacteria, colorectal cancer, DNA Sequencing, Dr. Nicholas Chia, gut bacteria, mayo clinic, Mayo Clinic Center for Individualized Medicine
February 14, 2019
When the shoelaces fray: short telomere syndromes
Unlike gray hair, one of the most significant signs of aging is invisible to the naked eye. Deep inside cells, at the tips of thread-like chromosomes, structures known as telomeres protect chromosomes from deterioration—a bit like the way caps at the ends of shoelaces prevent fraying. Telomeres naturally shorten as people age. But sometimes, an […]
Tags: #Bone marrow failure, #Dr. Mrinal Patnaik, #short telomeres, aging, Mayo Clinic Center for Individualized Medicine, Premyeloid
February 4, 2019
Meet Chuanhe Yu, Ph.D.: searching for the genetic switches linked to disease
By Sharon Rosen
Chuanhe Yu, Ph.D. has always had an interest in genetics – the thousands of genes that make each of us unique. His research focuses on the growing field of epigenetics, which aims to better understand how environmental and lifestyle factors cause chain reactions, flipping the switch on genes and the instructions they provide to guide […]
Tags: #cancer biology, #cell biology, #DNA replication, #Dr. Chuanhe Yu, #epigenetics, #epigenome, #eSPAN model, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, cancer, center for individualized medicine, Epigenomics, mayo clinic
January 28, 2019
Triumph out of tragedy: A home screening test for cervical cancer
January is Cervical Health Awareness Month, a time to reflect on personalized approaches to preventing or treating cervical cancer. Harrowing stories of rampant sexual violence and high instances of cervical cancer in the Democratic Republic of Congo spurred Marina Walther-Antonio, Ph.D. to action. The emotional stories of survival and death triggered her desire to discover […]
Tags: #Cervical cancer, #Cervical cancer screening, #Democratic Republic of Congo, #HPV, #HPV screening, center for individualized medicine, Dr. Marina Walther-Antonio
January 14, 2019
Using brain organoids to uncover causes of neuropsychiatric disorders
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, […]
Tags: Alexej Abyzov, autism, brain organoids, mayo clinic, Mayo Clinic Center for Individualized Medicine, neuropsychiatric disorders, Ph.D., Research, Yale University
January 7, 2019
What do Yellowstone rocks teach us about kidney stones?
Mayo Clinic researchers are turning to Yellowstone National Park to unlock the secrets of kidney stones. Medical science long has been mystified by a cause and cure for this painful condition that affects more than 1 in 10 Americans. Mayo Clinic Center for Individualized Medicine and NASA Astrobiology Institute research finds kidney stones grow in dynamic […]
Tags: #Kidney stones, #NASA Astrobiology Institute, #Yellowstone National Park, Dr. Nicholas Chia, Mayo Clinic Center for Individualized Medicine, microbiome
December 17, 2018
Probiotics: one size does not fit all
The allure of probiotics can be hard to resist. Popular belief holds that when you take probiotics in a pill, powder or food, you boost your gut health with a powerful antidote to digestive diseases. But what exactly are probiotics, and how do you separate truth from theory? What does the research say? Purna Kashyap, […]
Tags: #digestive diseases, #Digestive disorders, #digestive system, #gut health, #probiotics, Dr. Purna Kashyap, Gut Microbiome, Mayo Clinic Center for Individualized Medicine
December 3, 2018
Meet Sanjay Bagaria, M.D.: new CIM associate director in Florida
By Sharon Rosen
Hindsight is 20/20.That saying rings true for surgical oncologist Sanjay Bagaria, M.D. As a premedical student at University of Michigan, he chose to major in Japanese studies, mastering thousands of characters and a new grammar structure to read the Japanese literature he loved. Looking back, that experience gave him the tools to view not only […]
Tags: #Associate director Center for Individualized Medicine, #basal-like breast cancer, #Dr. Sanjay Bagaria, #hyperthermic intraperitoneal chemotherapy (HIPEC) surgery, #Mayo Clinic Campus in Florida, #surgical oncologist, biomarkers, center for individualized medicine, mayo clinic, medical research