August 18, 2021

Uterine microbe found to have disease-causing behavior in endometrial cancer

By Susan Murphy Susan Murphy (@susanmurphy)

A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study.  “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is […]

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Tags: Endometrial cancer, genomics, individualized medicine, Omics

July 29, 2021

Transforming clinical practice and changing outcomes for brain tumor patients

By Robin Huiras-Carlson Robin Huiras-Carlson (@robinh)

For patients with glioma, life after brain tumor diagnosis can be daunting. Treatment might be intense and invasive or, conversely, impossible due to the tumor’s location, grade or lack of therapeutic response. The genetic variability of glioma and its more advanced relative glioblastoma has made genetic testing to effectively identify biomarkers associated with prognosis and […]

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July 15, 2021

Genetic variants influence migraine treatment response, according to new Mayo study

By Susan Murphy Susan Murphy (@susanmurphy)

Migraines affect nearly 40 million people in the U.S. Yet pinpointing an effective prophylactic medication ― the most commonly prescribed drugs for people diagnosed with migraines ― remains a long and complex process. Patients often cycle through medications for weeks or months until achieving a therapeutic response.  Now after years of slow progress in migraine […]

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April 19, 2021

Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients

By Susan Murphy Susan Murphy (@susanmurphy)

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next. In the study, published in Clinical Gastroenterology and Hepatology, researchers within the Mayo Clinic Center for Individualized Medicine found 1 in 6 patients with colorectal cancer had an inherited cancer-related […]

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March 18, 2021

New Framework Leads to Surprise in Early Human Development

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic and Yale University scientists have developed a minimally invasive process for studying early cell development in a living person. The team reconstructed the cell history of two adult volunteers from just after cell fertilization. They found that in the first cell divide — 29 years earlier for one volunteer and 66 years earlier […]

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Tags: cells, genome, individualized medicine, Research

March 17, 2021

Data show clear benefit from genetic testing before prescribing antiplatelet therapy

By Susan Murphy Susan Murphy (@susanmurphy)

By Terri Malloy Pharmacogenomics is a valuable tool for health care providers to help prescribe the right drug for the right patient to enhance efficacy and avoid side effects. New research, funded in part by the National Heart, Lung and Blood Institute (NHLBI), shows  a clear advantage of genetic testing in helping health care providers […]

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Tags: antiplatelet, antiplatelet medication, coronary heart disease, Genetic Testing, pharmacogenomics

March 7, 2021

On International Women’s Day, meet 8 trailblazing women in Mayo Clinic’s Center for Individualized Medicine

By Susan Murphy Susan Murphy (@susanmurphy)

In honor of International Women’s Day on March 8, Mayo Clinic’s Center for Individualized Medicine is celebrating the inspirational women who are taking on incredible challenges and leading the way to cure, connect and transform health care. International Women’s Day is dedicated to the social, economic, political, cultural and scientific achievements of women. This year’s […]

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Tags: #women's health, ALS, cancer, Genetic Testing, genomics, neurodegenerative disorders, rare disease, womens cancer

February 8, 2021

Mayo Clinic algorithm shows potential in individualizing treatment for depression

By Susan Murphy Susan Murphy (@susanmurphy)

Finding an effective antidepressant medication for people diagnosed with depression, also called major depressive disorder, is often a long and complex process of “try and try again” ― going from one prescription to the next until achieving a therapeutic response. This complex disease, which affects more than 16 million people in the U.S., can cause […]

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Tags: #algorithm, #Artificial Intelligence, depression, Genetics, major depressive disorder

January 19, 2021

Mayo researchers explore genetics behind COVID-19 outcomes

By Susan Murphy Susan Murphy (@susanmurphy)

Some patients with COVID-19 experience severe complications, such as organ damage, shortness of breath, neurological impairment and chronic fatigue. A team of researchers within Mayo Clinic Center for Individualized Medicine is contributing to the global effort of using advanced genetic sequencing to find out which genes influence disease outcomes. “Our findings will be crucial in […]

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Tags: covid-19, Genetic Testing, Genetics, Genomic Research, individualized medicine, Research

November 30, 2020

Mayo study shows gene sequencing, translational research improves diagnosis rates

By Colette Gallagher Colette Gallagher (@colettegallagher)

Many patients with unsolved medical mysteries often undergo genetic testing, but the tests do not always provide a conclusive diagnosis. The term “diagnostic odyssey” describes the series of clinical consultations and testing that patients with undiagnosed disorders often receive in search of a genetic diagnosis. To help these patients, Mayo Clinic researchers embarked on a […]

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Tags: diagnostic odyssey, Dr. Eric Klee, Dr. Konstantinos Lazaridis, gene sequencing, mayo clinic, Mayo Clinic Center for Individualized Medicine, translational omics

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