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January 9, 2020

Mayo Clinic to sequence 100K participants to build genomic database for improved care and research in collaboration with Helix

By Colette Gallagher Colette Gallagher

Mayo Clinic is creating a library of genomic sequencing data on 100,000 consented Mayo Clinic participants to advance research and patient care. “We believe that whole exome sequencing has the potential to reveal predispositions to health problems and enable earlier use of preventive measures throughout a person’s lifespan,” says  Keith Stewart, M.B., Ch.B., Carlson and […]

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December 30, 2019

In Florida, a powerhouse of cancer research

By Susan Murphy Susan Murphy

By Sara Nick The Mayo Clinic Cancer Center, which spans Mayo Clinic’s Arizona, Florida and Minnesota locations, has 10 distinct research programs funded by the National Cancer Institute that are centered on broad areas such as immunology and gene therapy, or specific tumor types such as brain and gastrointestinal. Each research topic is treated with a multidisciplinary approach that ties together science, clinical relevance […]

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Tags: #gastrointestinal cancer, cancer, Cancer Research, gene sequencing, immunology


December 16, 2019

Mayo Clinic researchers look at post menopause as key factor in endometrial cancer

By Colette Gallagher Colette Gallagher

Mayo Clinic researchers have identified a microbiome signature associated with endometrial cancer, which is in part promoted by post menopause. In a study, supported by Mayo Clinic Center for Individualized Medicine and published in Scientific Reports, researchers sought to understand how endometrial cancer risk factors alter the reproductive tract microbiome and endometrial cancer risk. “If […]

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Tags: cancer, Endometrial cancer, microbiome, Microbiome Program


December 11, 2019

In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test

By Susan Murphy Susan Murphy

For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]

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Tags: #sepsis, bacteria, bacterial cells, Genome Sequencing, individualized medicine


Nobel Laureates' discovery paves way for research and patient care at Mayo Clinic

November 21, 2019

Nobel Laureates’ discovery paves way for research and patient care at Mayo Clinic

By Susan Murphy Susan Murphy

Three pioneering scientists who won this year’s Nobel Prize in Physiology or Medicine for their discovery of how cells adapt to oxygen availability helped lay the foundation of research and patient care, enabling  a unique service at Mayo Clinic — the von Hippel-Lindau Clinic.  “The understanding of how the body senses oxygen in the tissue […]

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Tags: Cancer Research, cells, Oxygen, von Hippel-Lindau Clinic


October 21, 2019

What men need to know about breast cancer risk

By Colette Gallagher Colette Gallagher

Male breast cancer is a rare disease, comprising 1% of all breast cancers, but the number of men diagnosed is on the rise. “And there is an increasing appreciation of differences in the tumor biology of female breast cancer versus male breast cancer,” says Siddhartha Yadav, M.D., co-author of a Mayo Clinic study published in […]

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Tags: Genetic Testing, genomics, hereditary breast cancer, hereditary cancer, Male breast cancer, Mayo Clinic Center for Individualized Medicine, Sarah Kroc, Siddhartha Yadav


April 30, 2019

Sudden Cardiac Death: Defining the Risk for Surviving Relatives

By Barbara J. Toman Barbara J. Toman

A young person’s sudden death from cardiac arrest is doubly devastating. Just when family members are mourning the unexpected loss, they might also be wondering if the cause was inherited heart disease — and if they too are at risk. Often there’s no easy answer. Unlike certain cancers with strong links to a single gene […]

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Tags: #Genetic heart disease, #sudden cardiac death, Dr. Joseph Maleszewski, Mayo Clinic Center for Individualized Medicine


Rare, undiagnosed diseases are relatively common

April 16, 2019

Rare, undiagnosed diseases are relatively common

By Susan Buckles Susan Buckles

As many as 25 million Americans – about 1 in 13 people – suffer from a rare, undiagnosed condition.* April 29 has been designated Undiagnosed Disease Day to raise awareness that collectively, rare diseases are relatively common. People with a rare disease often spend years visiting different medical providers and clinics seeking answers to unexplained […]

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Tags: #Dr. Heidi Rehm, #genomic testing, #rare diseases, #Undiagnosed rare diseases, Bioinformatics, DNA Testing, Dr. Eric Klee, Human Genome Project, Mayo Clinic Center for Individualized Medicine


September 12, 2018

CIMCON18 is underway: 6 ways individualizing medicine is advancing patient care

By Susan Buckles Susan Buckles

ROCHESTER, Minn. — Individualized medicine is tapping the human genome in new ways to attack health care disorders, predict risk of disease, make an earlier diagnosis and identify precise therapies. Individualized medicine, also called precision medicine, uses people’s information about their genetic blueprints, lifestyles and environments to shape health care. On Wednesday, Sept. 12, Keith […]

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August 9, 2018

Take a (video) walk through the human genome

By Susan Buckles Susan Buckles

From understanding quirky personal traits to finding out risk for disease, your unique genetic code holds clues to your health and wellness. The Smithsonian Institute exhibit, “Genome: Unlocking Life’s Code,” on display in Rochester, can help you make sense of the A, C, T, and G’s that make up the DNA you inherited. Mayo Clinic […]

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Tags: #Genome: Unlocking Life's Code exhibit, Mayo Clinic Center for Individualized Medicine


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