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September 12, 2018

CIMCON18 is underway: 6 ways individualizing medicine is advancing patient care

By Susan Buckles susanbuckles

ROCHESTER, Minn. — Individualized medicine is tapping the human genome in new ways to attack health care disorders, predict risk of disease, make an earlier diagnosis and identify precise therapies. Individualized medicine, also called precision medicine, uses people’s information about their genetic blueprints, lifestyles and environments to shape health care. On Wednesday, Sept. 12, Keith […]

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August 9, 2018

Take a (video) walk through the human genome

By Susan Buckles susanbuckles

From understanding quirky personal traits to finding out risk for disease, your unique genetic code holds clues to your health and wellness. The Smithsonian Institute exhibit, “Genome: Unlocking Life’s Code,” on display in Rochester, can help you make sense of the A, C, T, and G’s that make up the DNA you inherited. Mayo Clinic […]

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Tags: #Genome: Unlocking Life's Code exhibit, Mayo Clinic Center for Individualized Medicine


March 6, 2018

Genetic testing to enhance multiple myeloma treatment

By Susan Buckles susanbuckles

Article by Barbara Toman Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month — a time to focus attention on the fight against multiple myeloma. Mayo Clinic is making significant advances with […]

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Tags: #Blood cancer, #Myeloma Action Month, center for individualized medicine, Dr. Keith Stewart, Genomic Research, individualized medicine, mayo clinic, Multiple Myeloma, Precision Medicine


February 13, 2018

Genetic cardiovascular disease: Is your family at risk?

By Susan Buckles susanbuckles

With cardiovascular disease a leading cause of death, it’s fair to say that many people have been touched by this disorder. Maybe a family member died suddenly of a heart attack, or a friend suffered a disabling stroke. February is American Heart Month, a great time to talk about the precision approach Mayo Clinic Center […]

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Tags: #Familial hypercholesterolemia, #FH, #Genetic risk, #High cholesterol, #Mayo Clinic Department of Cardioscular Diseases, #Mayo Clinic Department of Clinical Genomics, #Stroke, Cardiovascular Disease, Dr. Iftikhar Kullo, Genetic Testing, heart attack, Heart Disease


January 23, 2018

A new way of capturing the molecular alterations of cancer

By Susan Buckles susanbuckles

Mayo Clinic researchers have a new way of plotting how cancer has progressed deep within a patient’s genetic blueprint. It’s a new graphing method called the Genome U-plot that reveals genetic changes taking place on a molecular level. The Genome U-plot’s two-dimensional layout and high spacial resolution make it possible to show chromosomal deletions, breaks, […]

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Tags: Biomarker Discovery, cancer, Dr. George Vasmatzis, Genetics, genomic medicine, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine


January 15, 2018

Artificial intelligence: Will a machine pick your next medication?

By Susan Buckles susanbuckles

What once may have seemed like a scene from a 22nd century sci-fi movie is reality today. High-speed, big data processing computers combine artificial intelligence with human know-how to crack complex health care conditions. This deep computer analysis may unveil new patterns that could bolster your health care provider’s ability to prescribe precise therapies, make […]

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Tags: #Artificial Intelligence, #Center for Computational Biotechnology and Genomic Medicine, #Dr. Ravishankar Iyer, #Machine learning, antidepressants, depression, Dr. Liewei Wang, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine, Precision Medicine, University of Illinois at Urbana-Champaign


January 2, 2018

Finding individualized treatments in liver disease and beyond

By Sharon Rosen sharonhrosen

In 1999, as a promising young physician-scientist, Konstantinos Lazaridis, M.D. was given an opportunity for additional research training as a Mayo Clinic Scholar. With the goal to establish an innovative, research program on liver disease in the Division of Gastroenterology and Hepatology his mentors suggested he make a choice between studying human genomics and hepatitis […]

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Tags: #Dr. Eric Lander, #family registry, #Mayo Clinic Clinomics Program, #PBC, #primary biliary cholangitis, #primary scleroscing cholangitis, #PSC, center for individualized medicine, Dr. Francis Collins, Dr. Konstantinos Lazaridis, Liver disease, mayo clinic


December 18, 2017

Three strikes, then a home run: Paige’s path to a diagnosis

By Susan Buckles susanbuckles

Paige Whorton’s zeal for life is infectious. “I like parasailing, exploring, and zip lining — daredevil stuff,” she says with a giggle. However, pain in her joints, building for years, was slowing her down. “My bones and joints would hurt when I would run. I couldn’t do anything fun with friends. It was more like, […]

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Tags: #Dr. Brendan Lanpher, #rare diseases, DNA Testing, Genetic Testing, Lysosomal Storage disease, Maroteaux-Lamy syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, mucopolysaccharidosis type VI


December 12, 2017

4 key things to know about the possibilities, pitfalls of gene editing

By Susan Buckles susanbuckles

ROCHESTER, Minn. — Gene editing has captivated scientists and medical providers with tantalizing visions of wiping out debilitating inherited diseases. Could conditions like Huntington’s disease, for example, be cured by using a tool that acts as a “molecular scissors” to remove and replace disease-causing DNA? Or, would gene editing tempt some to engineer designer babies […]

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Tags: #CRISPR-Cas9, #Dr. Megan Allyse, #Genetic diseases, #Inherited disease, Bioethics, gene editing, mayo clinic, Mayo Clinic Center for Individualized Medicine


November 2, 2017

Mayo Clinic researchers find genetic pathways to individualized treatment for advanced prostate cancer

By Susan Buckles susanbuckles

Researchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced prostate cancer. This discovery can guide health care providers to individualized treatments for castration-resistant prostate cancer, a deadly disease that does not respond to standard hormone therapy. Several U.S. Food and Drug […]

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Tags: Advanced prostate cancer, castration-resistant prostate cancer, center for individualized medicine, Dr. Keith Stewart, Dr. Liewei Wang, Dr. Manish Kohli, individualized medicine, medical research, personalized medicine, Precision Medicine, Prostate Cancer, RNA sequencing


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