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November 25, 2020

Grandma, gravy and genes: this Thanksgiving, learn your family’s health history

By Susan Murphy Susan Murphy

With Covid-19 cases rising, many families are changing their Thanksgiving Day plans to virtual gatherings to share memories, milestones and laughter. Researchers within Mayo Clinic Center for Individualized Medicine are also urging people to use part of this time to discuss their family’s health history…it could save a life. Thanksgiving Day marks Family Health History […]

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Tags: Genetic Testing, hereditary, hereditary cancer, hereditary diseases


November 23, 2020

Diversifying genomic medicine beyond genes

By Colette Gallagher Colette Gallagher

The work to improve health and health care is ongoing and ever-evolving. It takes many shapes, from streamlining delivery to improving care and pursuing inclusive medical research to help develop precision medicine for all populations. This was a key element of the Arizona Return of Actionable Variants Empirical, or RAVE, study, which brought genomic medicine to […]

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Tags: Arizona State University, Dr. Iftikhar Kullo, Dr. Richard Sharp, eMERGE Network, Genetics, mayo clinic, Mayo Clinic Center for Individualized Medicine, Mountain Park Health Center


November 16, 2020

A World in a Grain of Sand: New Discoveries in Kidney Stones

By Colette Gallagher Colette Gallagher

The Mayo Clinic and Illinois Alliance for Technology-Based Healthcare has a 10-year history of collaborations that led to important new medical knowledge and treatments. Now, joint research at Mayo Clinic and the University of Illinois at Urbana-Champaign is suggesting new possibilities for treating and preventing painful kidney stones. “Our research collaboration with the University of […]

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Tags: Dr. Nicholas Chia, kidney stones, Mayo Clinic Center for Individualized Medicine, Microbiome Program, Research


November 11, 2020

Conquering cancer by targeting its genetic abnormalities

By Susan Murphy Susan Murphy

Joanne Garnett has harrowing memories of that life-changing day back in 1981. She was a 39-year-old land use planner living in Wyoming when she received a call from her doctor confirming she had uterine cancer.  “I was shocked, and it was strange because I didn’t fit any profile for uterine cancer,” Garnett recalls. “I got […]

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Tags: BRCA2, genetic, Genetic Testing, hereditary cancer, lynch syndrome


November 2, 2020

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations

By Susan Murphy Susan Murphy

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer […]

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Tags: cancer genomics, Cancer Research, Genetic Testing, Genetics, Individualizing Medicine, Inherited cancer, Research


October 30, 2020

Human Genome Project — ‘A race to the starting line’

By Susan Murphy Susan Murphy

This month marks the 30th anniversary of the launch of the Human Genome Project, an international endeavor that mapped the 3 billion DNA letters that make up the blueprint of human life. The ambitious project began in October 1990 and was completed in April 2003. Today, researchers and clinicians with Mayo Clinic Center for Individualized […]

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Tags: Genomic Sequencing, genomics, Human Genome Project, Omics


October 20, 2020

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

By Susan Murphy Susan Murphy

By Sara Tiner Cells in the body usually do what they’re told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body’s order to expire: senescent cells. Sometimes called “zombie cells” for their undead lingering, senescent cells have triggered the body’s kill […]

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Tags: biomarkers, cells, individualized medicine, Research


October 15, 2020

Research into Experimental COVID-19 Therapeutics Explained

By Susan Murphy Susan Murphy

By Sara Tiner COVID-19 can affect people in a number of ways. Some can be infected and have no symptoms ― what’s known as being asymptomatic. Others have symptoms, but do not have a serious illness. And some can require hospitalization for intensive complications. For those with symptoms or those who are progressing to hospitalization, […]

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Tags: covid-19, individualized medicine


October 5, 2020

Center for Individualized Medicine 9th annual conference: Innovate. Connect. Transform.

By Susan Murphy Susan Murphy

By Jennifer O’Hara It has been a remarkable year of discoveries and medical advances at Mayo Clinic’s Center for Individualized Medicine. Some innovations include personalized treatments for cancer and rare diseases, and the development of lifesaving artificial intelligence algorithms. All of the center’s efforts are driven by advanced genetic analysis and aimed at providing patients with […]

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Tags: artificial intelligence, genomics, individualized medicine, microbiome


September 15, 2020

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: bacteria, Gut Microbiome, individualized medicine, Microbiome Program


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