Dec 10, 2018

RIGHT 10K: Blazing a trail to health care's future

By Barbara J. Toman @barbaratoman
Mayo Clinic's Center for Individualized Medicine (CIM) is nearing the finish line of the first stage of its unique RIGHT 10K study—an effort that doesn't involve running shoes but nevertheless is paving the way to prescribing medications matched to a person’s genetic code. RIGHT 10K is a clinical research project [...]
RIGHT 10K: Blazing a trail to health care's future
Dec 3, 2018

Meet Sanjay Bagaria, M.D.: new CIM associate director in Florida

By Sharon Rosen @sharonhrosen
Hindsight is 20/20.That saying rings true for surgical oncologist Sanjay Bagaria, M.D. As a premedical student at University of Michigan, he chose to major in Japanese studies, mastering thousands of characters and a new grammar structure to read the Japanese literature he loved. Looking back, that experience gave him the [...]
Meet Sanjay Bagaria, M.D.: new CIM associate director in Florida
Nov 26, 2018

Mayo Clinic discovery advances potential individualized treatment for mesothelioma

By Susan Buckles @susanbuckles
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy,  researchers at the Mayo Clinic Center for Individualized Medicine  have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex [...]
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Nov 19, 2018

Gene therapy: potential and pitfalls

By Susan Buckles @susanbuckles
Research is advancing gene therapy as a possible treatment or eventual cure for genetic diseases that bedevil modern science. Gene therapy was conceived over 20 years ago, and until recently, remained largely in the research lab. But gene therapy products are now beginning to be approved by the U.S. Food [...]
Gene therapy:  potential and pitfalls
Nov 12, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher @colettegallagher
Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report [...]
Novel data-driven approach for precision medicine
Nov 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen @sharonhrosen
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard [...]
Pharmacogenomics: finding the right drug, dose for cancer therapy
Oct 29, 2018

BEAUTY trial charts an individualized path to breast cancer treatment

By Susan Buckles @susanbuckles
Article by Julie Janovsky Mason Watch Elena’s story here:   Six years ago, Elena Blevins discovered a lump on her right breast as she was getting dressed. "At first I thought it was cyst," she says, initially dismissing the lump as she focused on her job and family. After several [...]
BEAUTY trial charts an individualized path to breast cancer treatment
Oct 23, 2018

Mayo Clinic research combines genetics and psychiatry to seek biomarkers for precise alcohol abuse therapies

By Susan Buckles @susanbuckles
Mayo Clinic research is bringing together knowledge of psychiatry, genetics, metabolomics, pharmacogenomics and artificial intelligence to seek biological markers associated with alcohol use disorder and treatment response. Finding the molecular drivers of alcohol use disorder commonly known as alcoholism, could help predict who is most likely to develop this disorder [...]
Mayo Clinic research combines genetics and psychiatry to seek biomarkers for precise alcohol abuse therapies
Oct 15, 2018

Personalized screening: finding and treating breast cancer sooner

By Sharon Rosen @sharonhrosen
October is Breast Cancer Awareness Month, a time to reflect on new, individualized approaches to detecting and treating a cancer that affects 1 in 8 American women. Deborah Rhodes, M.D. and her Mayo Clinic colleagues are working to identify the best targeted screening tools and guidelines for women with a [...]
Personalized screening: finding and treating breast cancer sooner
Oct 10, 2018

The right diet for you... or for your gut microbes?

By Susan Buckles @susanbuckles
  Article by Sara Tiner The right diet, obesity and gut health are topics patients, clinicians and scientists wrestle with every day. We want to eat a good diet and lose weight or avoid weight gain, so our health span matches our life span. But statistics suggest we struggle. To [...]
The right diet for you... or for your gut microbes?
Oct 4, 2018

Meet Lisa Schimmenti: Searching for drug therapies to treat hearing loss

By Sharon Rosen @sharonhrosen
Lisa Schimmenti, M.D. has always been fascinated with Helen Keller and all she accomplished, in spite of being blind and deaf from a very young age. As the newly appointed chair of Mayo Clinic’s Department of Clinical Genomics and a medical geneticist, Dr. Schimmenti cares for patients with similar conditions. In [...]
Meet Lisa Schimmenti: Searching for drug therapies to treat hearing loss
Oct 1, 2018

Mayo Clinic GeneGuide DNA testing application provides genetic testing, insights backed by Mayo Clinic expertise

By Colette Gallagher @colettegallagher
Today Mayo Clinic launched a new effort to raise awareness for genetic testing and how that may affect health and risk for disease. Mayo Clinic GeneGuide combines genetic testing with a web-based educational application to help consumers understand information about their own genetic background. “The Mayo Clinic GeneGuide app puts [...]
Mayo Clinic GeneGuide DNA testing application provides genetic testing, insights backed by Mayo Clinic expertise
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