June 29, 2022
Mayo study validates threshold to determine when an antidepressant is ineffective
By Susan Murphy
Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.
Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine
June 10, 2019
Meet William Bobo, M.D. – taking the guesswork out of finding the right depression therapy
By Sharon Rosen
Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. That’s because it […]
Tags: #Artificial Intelligence, #Center for Individualized Mediicine, #Dr. Arjun Athreya, #Dr. William Bobo, #individualized mediicne, #Mayo Clinic and Illinois Alliance for Technology-Based Healthcare, #mood disorders, #predictive algorithm, #selective serotonin reuptake inhibitors, #targeted therapies, #Treatment response, antidepressants
January 15, 2018
Artificial intelligence: Will a machine pick your next medication?
What once may have seemed like a scene from a 22nd century sci-fi movie is reality today. High-speed, big data processing computers combine artificial intelligence with human know-how to crack complex health care conditions. This deep computer analysis may unveil new patterns that could bolster your health care provider’s ability to prescribe precise therapies, make […]
Tags: #Artificial Intelligence, #Center for Computational Biotechnology and Genomic Medicine, #Dr. Ravishankar Iyer, #Machine learning, antidepressants, depression, Dr. Liewei Wang, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine, Precision Medicine, University of Illinois at Urbana-Champaign
March 17, 2017
The power of pharmacogenomics: one physician’s ‘aha moment’
By Sharon Rosen
Seeing is believing – that saying is especially true for Fadi Shamoun, M.D., a consultant and assistant professor in the Department of Cardiovascular Diseases at Mayo Clinic’s campus in Arizona. Dr. Shamoun was aware of the potential value of pharmacogenomics testing, which examines how a patient’s genetic makeup could impact the way he or she […]
Tags: #anti-coagulation medication, #Dr. Fadi Shamoun, #drug-gene reactions, #PGx testing, #Warfarin, antidepressants, center for individualized medicine, mayo clinic, medical research, pharmacogenomics
September 30, 2016
Consulting your genetic blueprint to find the right medication for you
By Sharon Rosen
Selecting the wrong medication for a patient can have serious implications. For example, if you have depression, the wrong medication could actually cause dangerous side effects that make you feel worse. In fact, researchers in the growing field of pharmacogenomics, which identifies drug-gene reactions, have already discovered that an individual’s genetic characteristics can influence how […]
Tags: #drug-gene reactions, #JAMA, #mental illness, #PrecisionMedicine, antidepressants, center for individualized medicine, depression, Dr. Mark Frye, individualized medicine, mayo clinic, pharmacogenomics, Psychiatry
June 27, 2016
Mayo Clinic Introduces Precision Medicine in Psychiatry
By Jeff Briggs
The right drug at the right dose at the right time. Faithful readers of the Center for Individualized Medicine blog already know we’re talking again about pharmacogenomics, or PGx. As we’ve explored in previous posts, these “right” goals drive pharmacogenomics — how genetics influence a person’s response to medications. But can pharmacogenomics and precision medicine […]
Tags: antidepressants, center for individualized medicine, CYP2D6, depression, Dr. Mark Frye, Dr. Wayne Nicholson, genome, mental health, pharmacogenomics, Precision Medicine, Prozac, Psychiatry