Items Tagged ‘Biomarker Discovery Program’

May 7, 2019

Targeting bile duct cancer – meet Mitesh Borad, M.D.

By Sharon Rosen Sharon Rosen

The search for treatment targets for patients with bile duct cancer, also known as cholangiocarcinoma, has taken a 360 degree turn, offering new hope for patients. That’s according to Mitesh Borad, M.D., deputy director for Center for Individualized Medicine Biomarker Discovery Program at Mayo Clinic’s Arizona campus, Dr. Borad and his colleagues are using new […]

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Tags: #Dr. Mitesh Borad, #liver cancer, #targeted therapies, bile duct cancer, Biomarker Discovery Program, cholangiocarcinoma, fibroblast growth factor receptor (FGFR) inhibitors, Genetic Testing, genomics, Liquid biopsy, mayo clinic, Mayo Clinic Center for Individualized Medicine


May 10, 2016

Protein May Predict Response to Immunotherapy in Patients with Metastatic Melanoma

By Jeff Briggs Jeff Briggs

Biomedical research is a large part of the mission at Mayo Clinic and here at the Center for Individualized Medicine, as we wrote about in a recent blog. News of a study that was funded in part by the Center’s Biomarker Discovery Program was just announced that may help immunotherapy for patients with metastatic melanoma.  […]

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Tags: Bim, Bim protein, biomarker, Biomarker Discovery Program, center for individualized medicine, Dr. Haidong Dong, Dr. Roxana Dronca, immunotherapy, Melanoma, Metastatic melanoma


January 22, 2016

Genomic Rearrangement Drives Pancreatic Cancer

By Jeff Briggs Jeff Briggs

Pancreatic cancer remains the fourth leading cause of cancer-associated deaths in the United States. While prognosis has improved for other major cancers thanks to early diagnosis, better therapies and a more comprehensive knowledge of genetic factors, death rates from pancreatic cancer continue to rise. Roughly 90 percent of pancreatic cancers are ductal pancreatic adenocarcinomas (PDAC) […]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, cancer, center for individualized medicine, Dr. George Vasmatzis, genomic medicine, NIH, Pancreatic Cancer


October 21, 2015

How Genomics Will Change the Way We Treat Cancer Patients

By Jeff Briggs Jeff Briggs

Dr. George Vasmatzis Brings Biomarker Discovery to New Audience at TEDxMinneapolis Everyone knows someone who has or has had cancer — including George Vasmatzis, Ph.D., co-director of the Biomarker Discovery Program at the Mayo Clinic Center for Individualized Medicine. This experience led him eventually to the Mayo Clinic where today he searches for clues in […]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, cancer, center for individualized medicine, Dr. George Vasmatzis, TED talks, TEDxMinneapolis


Biomarkers 101 Part 2

July 1, 2014

Biomarkers 101 Part 2

By AJ Montpetit AJ Montpetit

    George Vasmatzis, Ph.D., and John Cheville, M.D., co-directors of the Biomarker Program at the Center for Individualized Medicine at Mayo Clinic, introduce us to the world and work of Biomarkers. The Biomarker Discovery Program is a multidisciplinary team that includes oncologists, surgeons, pathologists, molecular biologists, bioengineers, bioinformaticians and others. By combining expertise, the program takes a clinical […]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, Bladder Cancer, breast cancer, center for individualized medicine, dna test, DNA Testing, gene sequencing, genome science, genomic medicine, genomics


February 25, 2014

Faster Cancer Discoveries by Developing Speedier Tumor Analysis Software

By Mystery User

Researchers at Mayo Clinic have created a new key to unlocking secrets of the human genome. The Binary Indexing Mapping Algorithm, version 3 (BIMA V3) is a freely available computer algorithm that identifies alterations in tumor genomes up to 20 times faster and with 25 percent greater accuracy than other popular genomic alignment programs. BIMA […]

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Tags: BIMA, Binary Indexing Mapping Algorithm, Biomarker Discovery Program, Burrows-Wheeler Aligner, cancer, dna test, DNA Testing, gene sequencing, genome science, genomic medicine, genomics, individualized medicine


January 21, 2014

Genomics Opens Door for New Application of Breast Cancer Drug for Bladder Cancer Patients

By Mystery User

Researchers at Mayo Clinic have found amplification of the gene HER2, a known driver of some breast cancers, in a type of bladder cancer called micropapillary urothelial carcinoma (MPUC) and have shown that it’s presence is associated with particularly aggressive tumors. These findings suggest that administering trastuzumab to MPUC patients with HER2 amplification could improve outcomes, […]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, Bladder Cancer, breast cancer, center for individualized medicine, dna test, DNA Testing, gene sequencing, genome science, genomic medicine, genomics


November 21, 2013

ASCL1 And RET Expression Defines Clinically Relevant Subgroup Of Lung Adenocarcinoma

By Center for Individualized Medicine Center for Individualized Medicine

A recent publication, featuring the Director of the Biomarker Discovery Program at the Center for Individualized Medicine at Mayo Clinic, George Vasmatzis, examining the role of ASCL1 in the neuroendocrine differentiation of lung adenocarcinoma. The clinical significance of neuroendocrine differentiation in lung adenocarcinoma, and the most appropriate biomarkers for this assessment, has long been debated. In the […]

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Tags: ASCL1, biomarker, Biomarker Discovery, Biomarker Discovery Program, cancer, center for individualized medicine, chromogranin, DNA, George Vasmatzis, immunohistochemical, individualized medicine, Lung Cancer


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