Items Tagged ‘biomarkers’

October 20, 2020

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

By Susan Murphy Susan Murphy (@susanmurphy)

By Sara Tiner Cells in the body usually do what they’re told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body’s order to expire: senescent cells. Sometimes called “zombie cells” for their undead lingering, senescent cells have triggered the body’s kill […]

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Tags: biomarkers, cells, individualized medicine, Research

August 29, 2019

Gerstner awards boost research into rheumatoid arthritis, breast cancer

By Barbara J. Toman Barbara J. Toman (@barbaratoman)

Creating tools to identify optimal treatments for rheumatoid arthritis and breast cancer are focuses of the 2019 Gerstner Family Career Development Awards. This year’s awardees are Elena Myasoedova, M.D., Ph.D., a rheumatologist at Mayo Clinic’s Minnesota campus and Bhavika Patel, M.D., a radiologist at Mayo’s Arizona campus. Both researchers seek to apply data centric approaches […]

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Tags: #Artificial Intelligence, #personalized therapies, biomarkers, breast cancer, center for individualized medicine, circulating tumor DNA, Dr. Bhavika Patel, Dr. Elena Myasoedova, Genetics, genomics, Gerstner Family Career Development Awards, mayo clinic

July 19, 2017

Genetic testing for earlier diagnosis and treatment of rheumatoid arthritis

By Sharon Rosen Sharon Rosen (@sharonhrosen)

If you are one of the estimated 1.5 million Americans who suffer from rheumatoid arthritis, you know about the painful, swollen and stiff joints that are common symptoms of this chronic inflammatory disorder. Mayo Clinic has been a leader in discovering biomarkers – indicators of health and disease – that link rheumatoid arthritis to the […]

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Tags: #CIMCon17, #Dr. Carla Wijbrandts, #Dr. Paul-Peter Tak, #drug response, #drug safety, #Individualizing Medicine 2017, biomarkers, center for individualized medicine, Dr. Eric Matteson, individualized medicine, mayo clinic, Mayo Clinic Proceedings

May 19, 2017

Personalized care for aggressive breast cancers: 4 steps forward from the BEAUTY study

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Chemotherapy substantially reduces the chance that certain types of breast cancer will return or spread to other parts of the body and improves survival. Chemotherapy before surgery is a standard approach to treat women with aggressive breast cancer. However, chemotherapy does not shrink tumors in all women. Mayo Clinic researchers are turning to genomic sequencing […]

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Tags: #aggressive breast cancer, #chemotherapy-resistant cancer, #patient derived xenografts, #PDX, #personalized therapies, #xenografts, Beauty Study, biomarkers, breast cancer, center for individualized medicine, chemotherapy, DNA Sequencing

February 16, 2017

Transforming care for patients with bladder and kidney cancer

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Identifying unmet patient needs Physicians want to provide the best care for their patients, but they are often challenged by the limits of current medical capabilities. For example, bladder cancer can be difficult to diagnose, making it hard to find at an early stage when treatment is most effective. It can also be difficult to […]

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Tags: #Mayo's Transform the Practice Initiative, #Renal cancer, #team science, biomarkers, center for individualized medicine, Dr. Alexander Parker, kidney cancer, mayo clinic, medical research

July 7, 2016

Mayo Clinic Researcher Receives Distinguished Award for Pharmacogenomics Research

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Liewei Wang, M.D., Ph.D., Mayo Clinic professor of Pharmacology, received the highly prestigious Leon I. Goldberg Early Investigator Award for her pharmacogenomics research. Pharmacogenomics is the study of how a patient’s genes affect the body’s response to medication. She is the second Mayo Clinic faculty member to have received the award by the American Society for […]

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Tags: American Society for Clinical Pharmacology and Therapeutics, biomarkers, center for individualized medicine, Dr. James Ingle, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Dr. Richard Weinshilboum, Leon I. Goldberg Early Investigator Award, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics

January 22, 2016

Genomic Rearrangement Drives Pancreatic Cancer

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

Pancreatic cancer remains the fourth leading cause of cancer-associated deaths in the United States. While prognosis has improved for other major cancers thanks to early diagnosis, better therapies and a more comprehensive knowledge of genetic factors, death rates from pancreatic cancer continue to rise. Roughly 90 percent of pancreatic cancers are ductal pancreatic adenocarcinomas (PDAC) […]

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Tags: biomarker, Biomarker Discovery Program, biomarkers, cancer, center for individualized medicine, Dr. George Vasmatzis, genomic medicine, NIH, Pancreatic Cancer

December 29, 2015

Delivering on the Promise of Precision Medicine: 2015 Year in Review

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

  2015 was the year of precision medicine. “Individualized medicine is already providing profound changes in how we treat patients,” said Keith Stewart, M.B., Ch.B., the Carlson and Nelson Endowed Director of the Center for Individualized Medicine, as he opened the 2015 Individualizing Medicine Conference. “It is offering hope to people who had no hope, […]

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Tags: Biobank, biomarkers, breast cancer, center for individualized medicine, diagnostic odyssey, Dr. Aleksandar Sekulic, Dr. J. Craig Venter, Dr. Keith Stewart, Dr. Konstantinos Lazaridis, Dr. Richard Weinshilboum, Genome Sequencing, Gianrico Farrugia

December 21, 2015

Mayo Clinic Researchers Identify Potential Biomarkers for Bipolar I Disorder

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

Biomarkers are molecular substances in the body that can be used to indicate health or disease. These biomarkers can be found in tissue, blood, urine and other body fluids. Biomarkers can lead to individualized diagnosis and treatment. The Biomarker Discovery Program is one of the signature programs here at the Center for Individualized Medicine.  It […]

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Tags: biomarker, biomarkers, bipolar, bipolar I disorder, center for individualized medicine, Dr. Mark Frye

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