Items Tagged ‘breast cancer’

July 9, 2019

Mayo experts provide insights into how genes affect medication response

By Sharon Rosen sharonhrosen

Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response to medications.    […]

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Tags: #addiction, #anti-seizure medication, #Center for Individualized Mediicine, #Dr. Lauren Cornell, #Dr. Sanjay Bagaria, #Dr. William Freeman, #Dr. William Palmer, #drug-gene interactions, #epilepsy, #estrogen receptor positive breast cancer, #medical education, #neurological diseases


June 28, 2019

Can BioBanks Help Close Gaps in Health Outcomes?

By Barbara J. Toman barbaratoman

By definition, personalized medicine requires diversity. One-size-fits-all doesn’t work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic’s Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo’s medical research. Sangre Por Salud (Spanish for […]

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Tags: #Arizona State University, #diabetes, #disease risk, #Dr. Richard Caselli, #Giovanna Moreno Garzon, #Health Disparities, #high blood pressure, #Mayo Clinic Biobank, #Mountain Park Health Center, #obesity, #Sangre Por Salud, #underserved populations


June 3, 2019

Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment

By Sharon Rosen sharonhrosen

Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who can determine if you and your family members […]

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Tags: #cancer risk, #Center for Individualized Mediicine, #gastrointestinal cancer, breast cancer, colorectal cancer, Dr. Niloy "Jewel" Samadder, Genetic Testing, genomics, hereditary cancer, lynch syndrome, mayo clinic, Mayo Clinic Proceedings


May 29, 2019

Individualizing Medicine 2019 Conference – practical precision cancer care approaches for your patients

By Sharon Rosen sharonhrosen

Amidst the demands of providing care for patients with cancer, it can be challenging for oncologists and their care teams to keep up with the rapidly evolving field of genomics. Practical ways to apply the latest precision medicine discoveries is the focus of this year’s Individualizing Medicine Conference: Precision Cancer Care through Immunotherapy and Genomics, […]

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Tags: #CAR T-cell therapy, #CIMCon19, biliary cancer, breast cancer, center for individualized medicine, Dr. Alan Bryce, familial cancer syndromes, hematologic cancers, immunotherapies, Individualizing Medicine Conference 2019, Lung Cancer, lymphoma


November 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen sharonhrosen

Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]

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Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine


October 29, 2018

BEAUTY trial charts an individualized path to breast cancer treatment

By Susan Buckles susanbuckles

Article by Julie Janovsky Mason Watch Elena’s story here:   Six years ago, Elena Blevins discovered a lump on her right breast as she was getting dressed. “At first I thought it was cyst,” she says, initially dismissing the lump as she focused on her job and family. After several months, she became increasingly tired. […]

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Tags: #Breast Cancer Awareness Month, #Dr. Donald Northfelt, #Mayo Clinic Breast Clinic, Beauty Study, breast cancer, Mayo Clinic Arizona campus, Mayo Clinic Center for Individualized Medicine


October 15, 2018

Personalized screening: finding and treating breast cancer sooner

By Sharon Rosen sharonhrosen

October is Breast Cancer Awareness Month, a time to reflect on new, individualized approaches to detecting and treating a cancer that affects 1 in 8 American women. Deborah Rhodes, M.D. and her Mayo Clinic colleagues are working to identify the best targeted screening tools and guidelines for women with a higher risk of developing breast […]

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Tags: #breast cancer screening, #dense breast tissue, #Dr. Deborah Rhodes, #Dr. Michael O'Connor, #Dr. Myra Wick, #molecular breast imaging, 3-D mammograms, breast cancer, breast density, center for individualized medicine, Dr. Carrie Hruska, mayo clinic


August 27, 2018

Gerstner awards boost research into hereditary cancer, Parkinson’s disease

By Susan Buckles susanbuckles

Creating tools to detect cancer at an early stage and advancing research into the genetic links to Parkinson’s disease are focuses of the 2018 Gerstner Family Career Development Awards. This year’s winners are Niloy ‘Jewel’ Samadder, M.D., a gastroenterologist at Mayo’s Arizona campus whose research focuses on inherited cancer, and Fabienne Fiesel, Ph.D., a neurosciences […]

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Tags: #Parkinson's disease, breast cancer, colon cancer, Dr. Niloy "Jewel" Samadder, Gertsner Family Career Development Awards, hereditary cancer, Mayo Clinic Center for Individualized Medicine, ovarian cancer, Pancreatic Cancer


February 13, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher colettegallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. […]

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Tags: #CIMCon18, #clinical guidelines, #Clinical Pharmacogenetics Implementation Consortium, #CYP2D6 geneotype, #estrogen receptor positive breast cancer, #tamoxifen, #targeted therapies, breast cancer, center for individualized medicine, DNA Sequencing, Dr. Matthew Goetz, Genetic Testing


November 30, 2017

3 ways Mayo Clinic is advancing individualized approaches to breast cancer treatment

By Sharon Rosen sharonhrosen

By Sharon Rosen and Susan Buckles Approximately one out of eight American women will develop breast cancer during their lifetime. In the U.S., it is estimated that more than 315,000 women will be diagnosed this year with breast cancer. While statistics show fewer women are dying from the disease, breast cancer still remains the second […]

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Tags: #blood tests, #breast cancer screening, #cancer detection, #cancer treatment, #Dr. Ciara O'Sullivan, #Dr. Minetta Liu, #genetic factors, #individualized therapy, #liquid biopsies, #xenografts, Beauty Study, breast cancer


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