Items Tagged ‘Cancer Research’
November 2, 2020
Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations
By Susan Murphy 
Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer […]
Tags: cancer genomics, Cancer Research, Genetic Testing, Genetics, Individualizing Medicine, Inherited cancer, Research
June 1, 2020
Seeing cancer, but not through a microscope
By Susan Murphy
By Marla Broadfoot, Ph.D. / Discovery’s Edge Toward the end of the 19th century, a French doctor named Ernest Besnier coined the term “biopsy,” combining the Greek bios (life) and opsis (a sight). In the decades since, clinicians have performed countless biopsies on suspected cancer patients, all to catch a glimpse of cells on the […]
Tags: cancer, Cancer Research, Genetics, Research
March 5, 2020
Rise in kidney cancer spurs Mayo researcher’s urgency to improve patient outcomes
As a trainee oncologist, Thai Ho, M.D., Ph.D., was struck by the number of people he saw at a veterans’ hospital with kidney cancer. “It’s one of the cancers that disproportionately affects military personnel, possibly due to environmental exposures,” he says. The results can be devastating. “On average, patients with kidney cancer lose 12 years […]
Tags: cancer, Cancer Research, Epigenetic research, Epigenomics, kidney cancer, Research
February 20, 2020
Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention
By Susan Murphy
What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]
Tags: #endometrial biopsy, cancer, Cancer Research, Endometrial cancer, Epigenetic research, Epigenomics
December 30, 2019
In Florida, a powerhouse of cancer research
By Susan Murphy
By Sara Nick The Mayo Clinic Cancer Center, which spans Mayo Clinic’s Arizona, Florida and Minnesota locations, has 10 distinct research programs funded by the National Cancer Institute that are centered on broad areas such as immunology and gene therapy, or specific tumor types such as brain and gastrointestinal. Each research topic is treated with a multidisciplinary approach that ties together science, clinical relevance […]
Tags: #gastrointestinal cancer, cancer, Cancer Research, gene sequencing, immunology
November 21, 2019
Nobel Laureates’ discovery paves way for research and patient care at Mayo Clinic
By Susan Murphy
Three pioneering scientists, outside of Mayo Clinic, who won this year’s Nobel Prize in Physiology or Medicine for their discovery of how cells adapt to oxygen availability helped lay the foundation of research and patient care, enabling a unique service at Mayo Clinic — the von Hippel-Lindau Clinic. “The understanding of how the body senses […]
Tags: Cancer Research, cells, Oxygen, von Hippel-Lindau Clinic
November 26, 2018
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]
Tags: #Dr. Aaron Mansfield, #mesothelioma, Cancer Research, Dr. George Vasmatzis, Mayo Clinic Center for Individualized Medicine
June 19, 2018
Mayo Clinic discovers genetic links to pancreatic cancer
Pancreatic cancer is one of the most difficult forms of cancer to diagnose and treat. For many patients, the disease is not treatable through surgery and standard chemotherapy. New research published in JAMA, supported in part through the Mayo Clinic Center for Individualized Medicine, gives insight into the underlying genetic links to pancreatic cancer. Senior […]
Tags: #Dr. Fergus Couch, cancer genomics, Cancer Research, DNA Testing, Dr. Gloria Petersen, JAMA study, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualize Medicine, Mayo Clinic Department of Laboratory Medicine and Pathology, Pancreatic Cancer
October 11, 2016
New biomarker discovery approaches to improve patient care
Biomarkers are an important measure of health and disease that can help doctors understand how to more effectively treat cancerous tumors. The topic of TIGER-Bio, a new approach to biomarker discovery, came into the spotlight in a workshop on the final morning of Individualizing Medicine 2016: Advancing Care through Genomics, The session, TIGER-Bio: The Integrated […]
Tags: #3-D genomic models, #bomarker discovery, #Dr. Mark Truty, #Dr. Minetta Liu, #Dr. Mitesh Borad, #liquid biopsies, #xenograph models, Cancer Research, center for individualized medicine, DNA Sequencing, Dr. George Vasmatzis, Genomic Research
January 14, 2014
Pursuing Future Ventures in Biomarker Discovery
By Sam Smith 
Five business students from around the state have immersed themselves in our Biomarker Discovery Program where they are conducting commercial assessments of Mayo Clinic discoveries in cancer diagnostics. These students, who work with the Center for Individualized Medicine and Mayo Clinic Ventures, conduct a semester-long evaluation of molecular discoveries that could help oncologists better diagnose […]
Tags: biomarker, Biomarker Discovery, biomarkers, cancer, Cancer Research, individualized medicine, lymphoma, mayo clinic, Mayo Clinic Ventures, oncology, personalized care, personalized medicine