Items Tagged ‘cancer’

March 5, 2020

Rise in kidney cancer spurs Mayo researcher’s urgency to improve patient outcomes

By Barbara J. Toman Barbara J. Toman

As a trainee oncologist, Thai Ho, M.D., Ph.D., was struck by the number of people he saw at a veterans’ hospital with kidney cancer. “It’s one of the cancers that disproportionately affects military personnel, possibly due to environmental exposures,” he says. The results can be devastating. “On average, patients with kidney cancer lose 12 years […]

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Tags: cancer, Cancer Research, Epigenetic research, Epigenomics, kidney cancer, Research


February 20, 2020

Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention

By Susan Murphy Susan Murphy

What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]

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Tags: #endometrial biopsy, cancer, Cancer Research, Endometrial cancer, Epigenetic research, Epigenomics


February 11, 2020

7 ways Mayo Clinic is leading to cure, connect and transform health care

By Susan Murphy Susan Murphy

  Mayo Clinic Center for Individualized Medicine’s physicians and researchers are leading the way to cure, connect and transform health care by combining their expertise to solve serious or complex medical conditions. Here are seven innovative ways the Center’s investigators are working together to provide patients with answers, treatment options and optimism.   Cultivating cutting-edge […]

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Tags: Biobank, cancer, cancer genomics, Epigenomics, Genomic Sequencing, infections, microbiome, rare disease


December 30, 2019

In Florida, a powerhouse of cancer research

By Susan Murphy Susan Murphy

By Sara Nick The Mayo Clinic Cancer Center, which spans Mayo Clinic’s Arizona, Florida and Minnesota locations, has 10 distinct research programs funded by the National Cancer Institute that are centered on broad areas such as immunology and gene therapy, or specific tumor types such as brain and gastrointestinal. Each research topic is treated with a multidisciplinary approach that ties together science, clinical relevance […]

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Tags: #gastrointestinal cancer, cancer, Cancer Research, gene sequencing, immunology


December 16, 2019

Mayo Clinic researchers look at post menopause as key factor in endometrial cancer

By Colette Gallagher Colette Gallagher

Mayo Clinic researchers have identified a microbiome signature associated with endometrial cancer, which is in part promoted by post menopause. In a study, supported by Mayo Clinic Center for Individualized Medicine and published in Scientific Reports, researchers sought to understand how endometrial cancer risk factors alter the reproductive tract microbiome and endometrial cancer risk. “If […]

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Tags: cancer, Endometrial cancer, microbiome, Microbiome Program


February 4, 2019

Meet Chuanhe Yu, Ph.D.: searching for the genetic switches linked to disease

By Sharon Rosen Sharon Rosen

Chuanhe Yu, Ph.D. has always had an interest in genetics – the thousands of genes that make each of us unique. His research focuses on the growing field of epigenetics, which aims to better understand how environmental and lifestyle factors cause chain reactions, flipping the switch on genes and the  instructions they provide to guide […]

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Tags: #cancer biology, #cell biology, #DNA replication, #Dr. Chuanhe Yu, #epigenetics, #epigenome, #eSPAN model, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, cancer, center for individualized medicine, Epigenomics, mayo clinic


January 23, 2018

A new way of capturing the molecular alterations of cancer

By Susan Buckles Susan Buckles

Mayo Clinic researchers have a new way of plotting how cancer has progressed deep within a patient’s genetic blueprint. It’s a new graphing method called the Genome U-plot that reveals genetic changes taking place on a molecular level. The Genome U-plot’s two-dimensional layout and high spacial resolution make it possible to show chromosomal deletions, breaks, […]

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Tags: Biomarker Discovery, cancer, Dr. George Vasmatzis, Genetics, genomic medicine, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine


November 7, 2017

Twenty-first century precision medicine cancer care

By Sharon Rosen Sharon Rosen

As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]

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Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings


October 10, 2017

#CIMCon 17 is underway

By Sharon Rosen Sharon Rosen

“Genomic medicine is already part of mainstream medical care,” says  A. Keith Stewart, M.B., Ch.B., in his opening remarks at the sixth Individualizing Medicine 2017: Advancing Care Through Genomics, a conference hosted by the Mayo Clinic Center for Individualized Medicine. Dr. Stewart, the Carlson and Nelson director of the Center for Individualized Medicine, kicked off the conference yesterday […]

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Tags: #cell-free DNA testing, #CIMCon17, #Dr. David Ledbetter, #Geisinger Health System, #genomic testing, #Individualizing Medicine Conference 2017, #liquid biopsies, #MyCode Community Health Initiative, #rare diseases, cancer, center for individualized medicine, Dr. Keith Stewart


October 5, 2017

#CIMCon17: learn from experts moving genomic discoveries into patient care

By Sharon Rosen Sharon Rosen

Mayo Clinic is a leader in moving important advancements in precision medicine from the laboratory into patient care, offering hope and healing. The Individualizing Medicine Conference: Advancing Care Through Genomics gives medical providers and scientists the opportunity to learn firsthand the newest ways genomic medicine is improving care for patients. The Mayo Clinic Center for […]

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Tags: #CIMCon17, #Consumer genomics, #Dr. David Ledbetter, #Dr. David Relman, #Dr. Judy Cho, #Dr. Rachel Tyndale, #Dr. Rob Knight, #Dr. Robert Green, #Dr. Stephanie Devaney, #Dr. William Gahl, #genomic testing, #Home DNA tests


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