Items Tagged ‘cancer’

February 4, 2019

Meet Chuanhe Yu, Ph.D.: searching for the genetic switches linked to disease

By Sharon Rosen Sharon Rosen

Chuanhe Yu, Ph.D. has always had an interest in genetics – the thousands of genes that make each of us unique. His research focuses on the growing field of epigenetics, which aims to better understand how environmental and lifestyle factors cause chain reactions, flipping the switch on genes and the  instructions they provide to guide […]

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Tags: #cancer biology, #cell biology, #DNA replication, #Dr. Chuanhe Yu, #epigenetics, #epigenome, #eSPAN model, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, cancer, center for individualized medicine, Epigenomics, mayo clinic


January 23, 2018

A new way of capturing the molecular alterations of cancer

By Susan Buckles Susan Buckles

Mayo Clinic researchers have a new way of plotting how cancer has progressed deep within a patient’s genetic blueprint. It’s a new graphing method called the Genome U-plot that reveals genetic changes taking place on a molecular level. The Genome U-plot’s two-dimensional layout and high spacial resolution make it possible to show chromosomal deletions, breaks, […]

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Tags: Biomarker Discovery, cancer, Dr. George Vasmatzis, Genetics, genomic medicine, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine


November 7, 2017

Twenty-first century precision medicine cancer care

By Sharon Rosen Sharon Rosen

As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]

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Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings


October 10, 2017

#CIMCon 17 is underway

By Sharon Rosen Sharon Rosen

“Genomic medicine is already part of mainstream medical care,” says  A. Keith Stewart, M.B., Ch.B., in his opening remarks at the sixth Individualizing Medicine 2017: Advancing Care Through Genomics, a conference hosted by the Mayo Clinic Center for Individualized Medicine. Dr. Stewart, the Carlson and Nelson director of the Center for Individualized Medicine, kicked off the conference yesterday […]

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Tags: #cell-free DNA testing, #CIMCon17, #Dr. David Ledbetter, #Geisinger Health System, #genomic testing, #Individualizing Medicine Conference 2017, #liquid biopsies, #MyCode Community Health Initiative, #rare diseases, cancer, center for individualized medicine, Dr. Keith Stewart


October 5, 2017

#CIMCon17: learn from experts moving genomic discoveries into patient care

By Sharon Rosen Sharon Rosen

Mayo Clinic is a leader in moving important advancements in precision medicine from the laboratory into patient care, offering hope and healing. The Individualizing Medicine Conference: Advancing Care Through Genomics gives medical providers and scientists the opportunity to learn firsthand the newest ways genomic medicine is improving care for patients. The Mayo Clinic Center for […]

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Tags: #CIMCon17, #Consumer genomics, #Dr. David Ledbetter, #Dr. David Relman, #Dr. Judy Cho, #Dr. Rachel Tyndale, #Dr. Rob Knight, #Dr. Robert Green, #Dr. Stephanie Devaney, #Dr. William Gahl, #genomic testing, #Home DNA tests


October 3, 2017

Liquid biopsies: detecting and treating cancer sooner

By Sharon Rosen Sharon Rosen

What if a blood test could discover cancer before a tumor first appears or before the first signs of cancer recurrence are seen by a radiology study? In fact, these types of blood tests, often called liquid biopsies, are already changing clinical care for patients with cancer. Researchers and physicians in Mayo Clinic Center for […]

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Tags: #blood tests, #cancer treatment, #cell-free DNA testing, #CIMCon17, #circulating tumor cells, #Dr. Minetta Liu, #Individualizing Medicine 2017, #liquid biopsies, Advanced Cancer, breast cancer, cancer, cancer screening


September 27, 2017

A genetic approach to cancer treatment

By Sharon Rosen Sharon Rosen

Article by Kristin Clift The medical community has historically defined and treated cancer based on where it is found in the body, such as the breast, lung or colon. So what has changed?  The FDA has recently started to approve treatments based on the genetic makeup of cancer rather than where the cancer is located. […]

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Tags: #cancer treatment, #CIMCon17, #DNA analysis, #Genetic Epidemiology and Risk Assessment Program, #Individualizing Medicine 2017, #targeted therapies, Advanced Cancer, cancer, center for individualized medicine, DNA Sequencing, Dr. Alexander Parker, Genetic Testing


September 19, 2017

How does a genomic tumor board impact patient care?

By Colette Gallagher Colette Gallagher

The outcomes from a Mayo Clinic study published in Oncotarget found value in having an established genomic tumor board, and using genomics for certain patients. The experience of the Genomic Tumor Board has promoted an evolution in the practice according to Alan Bryce, M.D., a Mayo Clinic oncologist, and co-first author on the study. “There […]

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Tags: #cancer treatment, #CIMCon17, #Dr. Jan Egan, #genetic testing fees, #Genomic analysis, #Genomic Tumor Board, #Individualizing Medicine 2017, #targeted therapies, Advanced Cancer, cancer, center for individualized medicine, Dr. Alan Bryce


September 14, 2017

Q and A: How has genomics led to precision cancer care?

By Sharon Rosen Sharon Rosen

How has cancer care changed with advances in genomic medicine? For example, for patients diagnosed with melanoma today, will their treatment options be different than those that were available 10 or 15 years ago? These are some of the questions we posed to  Aleksandar Sekulic, M.D., Ph.D., associate director, Mayo Clinic Center for Individualized Medicine, […]

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Tags: #cancer treatment, #Genomic analysis, #pharmacogenomics testing, #targeted therapies, cancer, center for individualized medicine, Dr. Aleksandar Sekulic, Genetic Testing, genomics, mayo clinic, medical research, Melanoma


May 30, 2017

IMPRESS study: maximizing immunotherapy with precision biomarkers to fight cancer

By Susan Buckles Susan Buckles

Mayo Clinic researchers are doing a deep dive at the molecular level to maximize the potential of immunotherapy to fight cancer. Immunotherapy — using your body’s immune system to identify and attack cancer cells — is a promising treatment for many types of cancer. But it’s expensive, associated with potential side effects, and doesn’t work […]

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Tags: #Dr. Aaron Mansfield, #Dr. Minetta Liu, #Dr. Richard Joseph, cancer, center for individualized medicine, Dr. Alan Bryce, Dr. George Vasmatzis, Dr. Haidong Dong, Dr. Roxana Dronca, Dr. Svetomir Markovic, immunotherapy, mayo clinic


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