Items Tagged ‘center for individualized medicine’

September 22, 2022

Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research


September 15, 2022

Designing Personalized Vaccines to Combat Cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers are working to develop personalized therapeutic cancer vaccines that can potentially target each person’s distinctive tumor characteristics. The new approach, built on advances in genomic research and data analytics, holds transformative potential to boost the power of the immune system to identify and attack cancer cells. 

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Tags: Cancer Research, cancer vaccine, center for individualized medicine, Genetics, medical research, neoantigen, personalized medicine


September 7, 2022

What is the benefit of visiting a genetic counselor?

By Susan Murphy Susan Murphy (@susanmurphy)

By Cynthia Weiss DEAR MAYO CLINIC: My grandmother and mother, as well as an aunt and a cousin, have had breast cancer. Another cousin was diagnosed with colon cancer recently. It has been suggested that I undergo genetic counseling to determine my cancer risk. As a young man, is genetic testing necessary for me? What benefit […]

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, individualized medicine


August 31, 2022

Critical Questions About AI: A Researcher Takes Pulse of Clinicians, Patients

By Susan Murphy Susan Murphy (@susanmurphy)

Richard Sharp, Ph.D., director of Mayo Clinic’s Biomedical Ethics Research Program, is heading a team studying what people think about medical innovations like genetic testing, neuromodulation and now AI.

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Tags: center for individualized medicine, genomic medicine, medical research


August 16, 2022

Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Joe Dangor Researchers from the Mayo Clinic Comprehensive Cancer Center and the Mayo Clinic Center for Individualized Medicine are studying a rare genetic condition called Familial Adenomatous Polyposis (FAP) looking for potential ways to prevent colorectal cancer in the general population at an earlier more treatable stage. The researchers’ findings are published in GUT. “Colorectal cancer is the third most common […]

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Tags: center for individualized medicine, colon cancer, Dr. Niloy "Jewel" Samadder, genomics, individualized medicine, medical research


August 8, 2022

Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care

By Colette Gallagher Colette Gallagher (@colettegallagher)

Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic


August 1, 2022

New AI algorithm opens avenues for knowledge discoveries

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a proof-of-concept study published in Frontiers in Immunology, Hu Li, Ph.D., a Mayo Clinic Center for Individualized Medicine systems biologist, developed a new artificial intelligence (AI) algorithm which uses novel weight engineering methods to extract meaningful biological knowledge learned by AI models. He and his team applied the tool to breast cancer omic data […]

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Tags: Cancer Research, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine


July 25, 2022

Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]

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Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine


July 22, 2022

The new precision stewards? A research agenda for ethical, legal and social aspects of antimicrobial resistance

By Colette Gallagher Colette Gallagher (@colettegallagher)

In this blog synopsis,  Karen Meagher, Ph.D., Assistant Professor and Associate Director of Public Engagement for Mayo Clinic Biomedical Ethics Research Program writes about the ethical aspects of antimicrobial resistance. If only traditional susceptibility testing took less time. If only there was a way to get the most personalized microbial profile into the hands of […]

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Tags: center for individualized medicine, individualized medicine, mayo clinic


July 20, 2022

2022 Gerstner Awardee to investigate gut microbiome link to chemotherapy-induced nausea

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Singh is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract. 

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Tags: center for individualized medicine, genomic medicine, genomics


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