December 8, 2023
Mayo Clinic’s biomedical ethics team reaches milestone in patient-centered research
By Susan Murphy
As scientists at the Mayo Clinic Center for Individualized Medicine discover new ways to use genomic information in the diagnosis, treatment and prevention of disease, their progress will touch the lives of many Mayo Clinic patients. Since its inception, the center has recognized the importance of understanding the experiences of people who undergo genomic evaluation. […]
November 10, 2023
Pass the turkey — and your family health insights — this Thanksgiving
By Susan Murphy
Thanksgiving Day is also Family Health History Day, an annual national campaign to promote awareness of hereditary health traits in families. Has your grandmother, mother, aunt or sister had breast or ovarian cancer? Has your grandfather, father or uncle had prostate, breast or pancreatic cancer? Is there a history in your family of colon cancer, diabetes […]
Tags: center for individualized medicine, Genetics, medical research
October 18, 2023
17-gene signature linked to remission after triple-negative breast cancer treatment
By Susan Murphy
Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast Cancer Research, highlights the potential for further investigating this signature as a target for individualized medicine.
Tags: Biomedical research, center for individualized medicine, multi-omics
October 5, 2023
Mayo Clinic research uncovers epigenetic roots of digestive disorder associated with diabetes
By Susan Murphy
Living with diabetes can be challenging due to numerous potential complications, including the development of gastroparesis. The digestive disorder, which predominantly affects women, leads to a delay in stomach emptying, causing nausea, vomiting and feeling full. In a new preclinical study, scientists at the Mayo Clinic Center for Individualized Medicine have discovered insights into the […]
Tags: center for individualized medicine, Diabetes research, Epigenetic research
September 28, 2023
New gene markers detect Lynch syndrome-associated colorectal cancer, Mayo Clinic study
By Susan Murphy
By Kelley Luckstein Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy. Studies are underway to determine if these genetic markers are in stool samples and, if so, how this could lead to a non-invasive screening option for patients with Lynch […]
Tags: center for individualized medicine, Dr. Niloy "Jewel" Samadder
September 12, 2023
New Mayo Clinic individualized medicine leader on a quest to bring cutting-edge medicine to all
By Susan Murphy
As a pulmonologist and genomic scientist, Victor Ortega, M.D., Ph.D., is leading a charge to breathe new life into precision medicine advancements. His mission is rooted in a deep commitment to health equities and inspired by his grandmother. “My grandmother died of asthma, and that should not have happened. She was Puerto Rican like me, […]
Tags: Biomedical research, center for individualized medicine, Dr. Victor Ortega, genomic medicine
August 31, 2023
Mayo Clinic cancer researchers targeting racial disparities in genomic data
By Susan Murphy
Standing at the forefront of Mayo Clinic’s genomics advancements, Yan Asmann, Ph.D., and Aaron Mansfield, M.D. are working to tailor the diagnosis and treatment of certain cancers to a person’s unique genomic makeup. As a bioinformatician, Dr. Asmann is pursuing individualized therapeutic cancer vaccines that target a person’s distinctive tumor characteristics. Dr. Mansfield, a […]
Tags: Biomedical research, center for individualized medicine
August 10, 2023
Mayo Clinic ‘mini-brain’ study reveals possible key link to autism spectrum disorder
By Susan Murphy
Using human “mini-brain” models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions. The specific cells are known as excitatory cortical neurons. The new study […]
Tags: Alexej Abyzov, autism, Biomedical research, center for individualized medicine, genomic medicine, organoids
August 1, 2023
2023 Gerstner Awardee’s ‘evolutionary therapy’ targets pancreatic cancer treatment resistance
By Susan Murphy
Ryan Carr, M.D., Ph.D., a medical oncologist in Mayo Clinic’s Department of Oncology, is a recipient of the 2023 Gerstner Family Career Development Award. The competitive awards are presented annually by Mayo Clinic Center for Individualized Medicine to researchers conducting innovative investigations to predict, prevent, treat and cure diseases using individualized medicine approaches. Dr. Carr […]
Tags: Biomedical research, center for individualized medicine, Pancreatic Cancer
August 1, 2023
2023 Gerstner Awardee to investigate individualized treatment strategy for follicular lymphoma
By Susan Murphy
Patrizia Mondello, M.D., Ph.D., M.Sc., a physician-scientist in Mayo Clinic’s Department of Hematology, is a recipient of the annual 2023 Gerstner Family Career Development Award from the Mayo Clinic Center for Individualized Medicine. The competitive awards advance innovative research to predict, prevent, treat, and cure diseases using individualized medicine. Inspired by a 20-year-old woman named […]
Tags: Biomedical research, center for individualized medicine, genomic medicine