Items Tagged ‘chemotherapy’

November 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen sharonhrosen

Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]

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Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine


June 21, 2018

Taking action: using pharmacogenomics testing to individualize care for colorectal cancer

By Sharon Rosen sharonhrosen

Every day, Pashtoon Kasi, M.D., M.B.B.S. is inspired by his patients with colorectal cancer to deliver the best, individualized care to meet their unique needs. As an oncologist at Mayo Clinic’s campus in Florida, Dr. Kasi is seeing many of the growing number of younger patients – those in their 20’s, 30’s and 40’s – diagnosed with […]

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Tags: #CIMCon18, #clinical research, #drug-gene interactions, #Individualizing Medicine 2018, #medication side effects, #pharmacogenomics testing, #pre-emptive pharmacogenomics testing, center for individualized medicine, chemotherapy, colorectal cancer, Genetic Testing, mayo clinic


May 19, 2017

Personalized care for aggressive breast cancers: 4 steps forward from the BEAUTY study

By Sharon Rosen sharonhrosen

Chemotherapy substantially reduces the chance that certain types of breast cancer will return or spread to other parts of the body and improves survival. Chemotherapy before surgery is a standard approach to treat women with aggressive breast cancer. However, chemotherapy does not shrink tumors in all women. Mayo Clinic researchers are turning to genomic sequencing […]

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Tags: #aggressive breast cancer, #chemotherapy-resistant cancer, #patient derived xenografts, #PDX, #personalized therapies, #xenografts, Beauty Study, biomarkers, breast cancer, center for individualized medicine, chemotherapy, DNA Sequencing


March 15, 2017

Mayo breast cancer study provides critical information on tumor sequencing and response to chemotherapy

By Sharon Rosen sharonhrosen

Article by Colette Gallagher, Public Affairs Mayo Clinic researchers reported in the Journal of the National Cancer Institute the results of the Breast Cancer Genome-Guided Therapy (BEAUTY) study designed to help researchers and physicians better understand why current standard chemotherapy stops breast cancer in some women but fails in others. Tumor sequencing is increasingly used to select […]

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Tags: #Breast Cancer Genome-Guided Therapy study, #DNA sequencing tests, #Journal of the National Cancer Institute, #tumor sequencing, breast cancer, center for individualized medicine, chemotherapy, Dr. Judy Boughey, Dr. Matthew Goetz, mayo clinic, Mayo Clinic Cancer Center, medical research


October 15, 2013

From Twitter To Practice

By AJ Montpetit ajmontpetit

  Today’s Twitter Chat with Dr. Richard Besser from ABC on the topic of Breast Cancer touched on the need for mammogram testing and the need for patient education. The discussion also took a turn to BRCA testing, as well as genetic testing. One area that the Center for Individualized Medicine focuses on is understanding why […]

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Tags: ABC, beauty project, breast cancer, Breast Cancer Genome-Guided Therapy, center for individualized medicine, chat, chemotherapy, Dr. Richard Besser, Genomic Sequencing, neoadjuvant therapy, personalized care, personalized medicine


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