March 29, 2021
Mayo researchers use AI to reveal causes of complex diseases
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine have developed an artificial intelligence (AI) platform that can uncover causal drivers and relationships embedded within complex biomedical data. Nicholas Chia, Ph.D., John Kalantari, Ph.D., and Kia Khezeli, Ph.D., recently tested their machine-learning framework, called Causal Relation and Inference Search Platform (CRISP) on multiomic colorectal cancer samples […]
Tags: #algorithm, #Artificial Intelligence, cancer, colon cancer, colorectal cancer, multi-omics, rare disease
June 16, 2020
Mayo Clinic, NASA team up to test AI algorithm on colorectal cancer
By Susan Murphy
Mayo is working with NASA to sequence the path of cancer — from what causes it to what drives it, and potentially how to prevent it. Mayo researchers and NASA Frontier Development Lab data scientists are embarking on a research sprint this month to optimize an artificial intelligence (AI) algorithm for colorectal cancer and possibly […]
June 3, 2019
Identifying hereditary cancer risk: genetic testing can lead to better screening, earlier treatment
By Sharon Rosen
Do you have family members who have been diagnosed with gastrointestinal, breast or ovarian cancer? According to a recent Mayo Clinic study, nearly 5% to 10% of these cancers can be hereditary. That’s why it is important to share your family medical history with your physician, who can determine if you and your family members […]
Tags: #cancer risk, #Center for Individualized Mediicine, #gastrointestinal cancer, breast cancer, colorectal cancer, Dr. Niloy "Jewel" Samadder, Genetic Testing, genomics, hereditary cancer, lynch syndrome, mayo clinic, Mayo Clinic Proceedings
April 2, 2019
Purna Kashyap, M.B.B.S. – testing the bugs within to maintain health, detect and treat disease
By Sharon Rosen
The use of microbiome testing – which analyzes the trillions of bacteria in and on the body – is on the move. It’s going from the research lab into the clinic to help guide patient care. DNA testing technologies have revolutionized researchers’ ability to identify individual bacterial strains driving disease. Now genomic testing is helping […]
Tags: #blood sugar levels, #Center for Individualized Medicine Microbiome Program, #diabetes, #digestive health, #glucose levels, #inflammatory bowel disease, #obesity, #personalized diet, c. difficile, center for individualized medicine, colorectal cancer, Dr. Purna Kashyap
March 5, 2019
By Sharon Rosen
Space-age technologies, DNA sequencing and artificial intelligence – all tools for discovery that Nicholas Chia, Ph.D. and his team are using to push the envelope and improve care for complex diseases like colorectal cancer. They’re collaborating with scientists from NASA to uncover how the microbiome – the trillions of microbes in and on the body […]
Tags: #ecology, #genomic testing, #Kidney stones, #microbial ecology, #systems biology, bacteria, colorectal cancer, DNA Sequencing, Dr. Nicholas Chia, gut bacteria, mayo clinic, Mayo Clinic Center for Individualized Medicine
November 5, 2018
Pharmacogenomics: finding the right drug, dose for cancer therapy
By Sharon Rosen
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]
Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine
June 21, 2018
Taking action: using pharmacogenomics testing to individualize care for colorectal cancer
By Sharon Rosen
Every day, Pashtoon Kasi, M.D., M.B.B.S. is inspired by his patients with colorectal cancer to deliver the best, individualized care to meet their unique needs. As an oncologist at Mayo Clinic’s campus in Florida, Dr. Kasi is seeing many of the growing number of younger patients – those in their 20’s, 30’s and 40’s – diagnosed with […]
Tags: #CIMCon18, #clinical research, #drug-gene interactions, #Individualizing Medicine 2018, #medication side effects, #pharmacogenomics testing, #pre-emptive pharmacogenomics testing, center for individualized medicine, chemotherapy, colorectal cancer, Genetic Testing, mayo clinic
October 3, 2017
Liquid biopsies: detecting and treating cancer sooner
By Sharon Rosen
What if a blood test could discover cancer before a tumor first appears or before the first signs of cancer recurrence are seen by a radiology study? In fact, these types of blood tests, often called liquid biopsies, are already changing clinical care for patients with cancer. Researchers and physicians in Mayo Clinic Center for […]
Tags: #blood tests, #cancer treatment, #cell-free DNA testing, #CIMCon17, #circulating tumor cells, #Dr. Minetta Liu, #Individualizing Medicine 2017, #liquid biopsies, Advanced Cancer, breast cancer, cancer, cancer screening
March 23, 2017
Genetics and biology hold the keys to better screening, treatment of colon cancer
By Sharon Rosen
Colon cancer is the fourth most common form of cancer diagnosis in America. However, it is very treatable when caught in early stages. Throughout the month of March, Mayo Clinic is enlisting the help of a giant inflatable colon to help patients learn firsthand how colon cancer develops and the key role that screening plays […]
Tags: #Colon cancer screening, #colon cancer treatment, #Colon display, #Dr. Thorvardur Halfdanarson, #inherited colon cancer, #Katie Agre, #Mayo Clinic Cancer Education Program, center for individualized medicine, colon cancer, colorectal cancer, Dr. Nicholas Chia, Genetic Counselor
March 7, 2017
March 16: Strollin’ Colon – Colon Cancer Awareness Event
By Sharon Rosen
Do you know the facts about colon cancer – what types of screening tests are available to prevent or detect it early, whether you’re at risk, and if so, how it is treated? You can learn more by taking a walk through the inflatable Strollin’ Colon, which will be at all Mayo Clinic campuses through […]
Tags: #Center for Individualzied Medicine, #ColorectalCancer, #Dr. Thorvardur Halfdanarson, #Hereditary colorectal cancer, #Katherine Agre, #Microbiome research, #Strollin' Colon, colon cancer, colorectal cancer, Dr. Nicholas Chia, Genetic Counselor, Genetic Testing