Items Tagged ‘covid-19’
November 10, 2022
Multi-omics: A new model for identifying biomarkers to predict severe COVID-19 outcomes
In a groundbreaking study published in The Lancet Digital Health, Mayo Clinic investigators have developed a multiomic molecular method to predict clinical COVID-19 (SARS-CoV-2) outcomes better than traditional cytokines. Using a machine-learning-based prediction model, the team identified 102 biomarkers, which include several novel cytokines and other proteins, lipids, and metabolites. The discovery may help clinicians reliably […]
Tags: covid-19
July 25, 2022
Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19
By Susan Murphy 
Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine
July 15, 2022
BA.5 omicron variant fueling latest COVID-19 surge
By Susan Murphy
A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. The extensive research and surveillance operation involves conducting hundreds of sequences of the COVID-19 virus each week.
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, medical research
February 16, 2022
Mass spectrometry-based assay detects viral antigens directly from clinical specimens
By Susan Murphy
By Mayo Clinic Laboratories In a newly published study, a team from Mayo Clinic’s Advanced Diagnostics Laboratory has developed a mass spectrometry-based assay that’s able to detect COVID-19 (SARS-CoV-2) pathogens from human proteins with, remarkably, 98% sensitivity and 100% specificity. This is the first assay of its kind that can detect viral antigens “directly from clinical specimens” such […]
Tags: center for individualized medicine, covid-19, Dr. Akhilesh Pandey, Mayo Clinic Advanced Diagnostic Laboratory
January 18, 2022
Mayo’s COVID-19 Sequencing Command Center offers insights into ‘power of the virus’
By Susan Murphy
Tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19, is crucial for detecting and responding to emerging variants. A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of the extensive research and surveillance operation, conducting nearly 750 sequences of the COVID-19 virus each week.
Tags: center for individualized medicine, covid-19, Dr. Konstantinos Lazaridis, Dr. Purna Kashyap, Genetic Sequencing, sequencing
December 22, 2021
Patients hospitalized with COVID-19 who had a combination of high blood pressure, obesity, diabetes, or other conditions associated with metabolic syndrome were at much higher risk of acute respiratory distress syndrome and death, according to an international study published in JAMA Network Open.
September 20, 2021
Mayo Clinic leads biorepository core for new nationwide research on long-term symptoms of COVID-19
Mayo Clinic research is dedicated to finding solutions for patients who were infected with COVID-19 and the many affected by the long-term symptoms of COVID-19 ― what the National Institutes of Health (NIH) refers to as “long COVID” or post-acute sequelae. In response to great unmet patient need, the NIH launched a new research initiative […]
Tags: center for individualized medicine, covid-19, Dr. Mine Cicek, Dr. R.Ross Reichard, Dr. Ryan Hurt, Dr. Stephen Thibodeau, Dr. Thomas Flotte, individualized medicine, long-COVID, mayo clinic, mayo clinic laboratories, medical research
January 19, 2021
Mayo researchers explore genetics behind COVID-19 outcomes
By Susan Murphy
Some patients with COVID-19 experience severe complications, such as organ damage, shortness of breath, neurological impairment and chronic fatigue. A team of researchers within Mayo Clinic Center for Individualized Medicine is contributing to the global effort of using advanced genetic sequencing to find out which genes influence disease outcomes. “Our findings will be crucial in […]
Tags: covid-19, Genetic Testing, Genetics, Genomic Research, individualized medicine, Research
January 13, 2021
Convalescent plasma antibody levels and the risk of death from COVID-19
By Susan Murphy
By Bob Nellis| ROCHESTER, Minn. – Mayo Clinic researchers and collaborators have found an association between administration of convalescent plasma containing high antibodies and lower mortality rates for hospitalized patients with COVID-19 who are not on ventilators. The findings, “Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19,” appear today in the New […]
October 15, 2020
Research into Experimental COVID-19 Therapeutics Explained
By Susan Murphy
By Sara Tiner COVID-19 can affect people in a number of ways. Some can be infected and have no symptoms ― what’s known as being asymptomatic. Others have symptoms, but do not have a serious illness. And some can require hospitalization for intensive complications. For those with symptoms or those who are progressing to hospitalization, […]
Tags: covid-19, individualized medicine