Items Tagged ‘depression’
October 4, 2022
Mayo study lays foundation to predict antidepressant response in people with suicide attempts
By Susan Murphy 
Mayo Clinic researchers have discovered that people with major depressive disorder and a history of attempted suicide have distinct biomarkers that correlate with their response to antidepressant therapy. The new findings, published in Frontiers Pharmacology, are key to individualized treatment strategies and early identification of patients who are at the highest risk for suicide. For […]
Tags: center for individualized medicine, depression, genomics, major depressive disorder, personalized medicine
June 29, 2022
Mayo study validates threshold to determine when an antidepressant is ineffective
By Susan Murphy
Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.
Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine
February 8, 2021
Mayo Clinic algorithm shows potential in individualizing treatment for depression
By Susan Murphy
Finding an effective antidepressant medication for people diagnosed with depression, also called major depressive disorder, is often a long and complex process of “try and try again” ― going from one prescription to the next until achieving a therapeutic response. This complex disease, which affects more than 16 million people in the U.S., can cause […]
Tags: #algorithm, #Artificial Intelligence, depression, Genetics, major depressive disorder
January 28, 2020
By Sharon Rosen
Patients suffering from depression, anxiety and substance use disorders often search for years to find treatment. Studies have shown that during this time gap, patients’ symptoms worsen, increasing their risk for other chronic illnesses, shortened lifespan and poor quality of life. Mayo Clinic statistical geneticist Joanna Biernacka, Ph.D. and her colleagues are working to change […]
Tags: #Mayo Clinic Biobank, anxiety, center for individualized medicine, depression, Genetic Testing, genomics, Joanna Biernacka, mayo clinic, Project Generation, psychiatric disorders, risk score, substance abuse disorder
July 9, 2019
Mayo experts provide insights into how genes affect medication response
By Sharon Rosen
Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care. Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response to medications. […]
Tags: #addiction, #anti-seizure medication, #Center for Individualized Mediicine, #Dr. Lauren Cornell, #Dr. Sanjay Bagaria, #Dr. William Freeman, #Dr. William Palmer, #drug-gene interactions, #epilepsy, #estrogen receptor positive breast cancer, #medical education, #neurological diseases
June 10, 2019
Meet William Bobo, M.D. – taking the guesswork out of finding the right depression therapy
By Sharon Rosen
Depression can touch every aspect of a person’s life – affecting the way they think, feel and behave. It is also the leading medical condition for those who complete suicide. Getting the right therapy is crucial. But for patients suffering from the disorder, finding an effective treatment often involves trial and error. That’s because it […]
Tags: #Artificial Intelligence, #Center for Individualized Mediicine, #Dr. Arjun Athreya, #Dr. William Bobo, #individualized mediicne, #Mayo Clinic and Illinois Alliance for Technology-Based Healthcare, #mood disorders, #predictive algorithm, #selective serotonin reuptake inhibitors, #targeted therapies, #Treatment response, antidepressants
January 15, 2018
Artificial intelligence: Will a machine pick your next medication?
What once may have seemed like a scene from a 22nd century sci-fi movie is reality today. High-speed, big data processing computers combine artificial intelligence with human know-how to crack complex health care conditions. This deep computer analysis may unveil new patterns that could bolster your health care provider’s ability to prescribe precise therapies, make […]
Tags: #Artificial Intelligence, #Center for Computational Biotechnology and Genomic Medicine, #Dr. Ravishankar Iyer, #Machine learning, antidepressants, depression, Dr. Liewei Wang, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine, Precision Medicine, University of Illinois at Urbana-Champaign
September 30, 2016
Consulting your genetic blueprint to find the right medication for you
By Sharon Rosen
Selecting the wrong medication for a patient can have serious implications. For example, if you have depression, the wrong medication could actually cause dangerous side effects that make you feel worse. In fact, researchers in the growing field of pharmacogenomics, which identifies drug-gene reactions, have already discovered that an individual’s genetic characteristics can influence how […]
Tags: #drug-gene reactions, #JAMA, #mental illness, #PrecisionMedicine, antidepressants, center for individualized medicine, depression, Dr. Mark Frye, individualized medicine, mayo clinic, pharmacogenomics, Psychiatry
June 27, 2016
Mayo Clinic Introduces Precision Medicine in Psychiatry
By Jeff Briggs
The right drug at the right dose at the right time. Faithful readers of the Center for Individualized Medicine blog already know we’re talking again about pharmacogenomics, or PGx. As we’ve explored in previous posts, these “right” goals drive pharmacogenomics — how genetics influence a person’s response to medications. But can pharmacogenomics and precision medicine […]
Tags: antidepressants, center for individualized medicine, CYP2D6, depression, Dr. Mark Frye, Dr. Wayne Nicholson, genome, mental health, pharmacogenomics, Precision Medicine, Prozac, Psychiatry