November 26, 2018
Mayo Clinic discovery advances potential individualized treatment for mesothelioma
Large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond to immunotherapy, researchers at the Mayo Clinic Center for Individualized Medicine have discovered. The research is published in the Journal of Thoracic Oncology. “What we’ve shown so far is that these large complex chromosomal rearrangements are frequent in […]
Tags: #Dr. Aaron Mansfield, #mesothelioma, Cancer Research, Dr. George Vasmatzis, Mayo Clinic Center for Individualized Medicine
January 23, 2018
A new way of capturing the molecular alterations of cancer
Mayo Clinic researchers have a new way of plotting how cancer has progressed deep within a patient’s genetic blueprint. It’s a new graphing method called the Genome U-plot that reveals genetic changes taking place on a molecular level. The Genome U-plot’s two-dimensional layout and high spacial resolution make it possible to show chromosomal deletions, breaks, […]
Tags: Biomarker Discovery, cancer, Dr. George Vasmatzis, Genetics, genomic medicine, genomics, mayo clinic, Mayo Clinic Center for Individualized Medicine
May 30, 2017
IMPRESS study: maximizing immunotherapy with precision biomarkers to fight cancer
Mayo Clinic researchers are doing a deep dive at the molecular level to maximize the potential of immunotherapy to fight cancer. Immunotherapy — using your body’s immune system to identify and attack cancer cells — is a promising treatment for many types of cancer. But it’s expensive, associated with potential side effects, and doesn’t work […]
Tags: #Dr. Aaron Mansfield, #Dr. Minetta Liu, #Dr. Richard Joseph, cancer, center for individualized medicine, Dr. Alan Bryce, Dr. George Vasmatzis, Dr. Haidong Dong, Dr. Roxana Dronca, Dr. Svetomir Markovic, immunotherapy, mayo clinic
April 6, 2017
Mayo Clinic investigators share precision medicine research and practice at 10th ISABS Conference
By Sharon Rosen
Mayo Clinic Center for Individualized Medicine physicians and scientists will join Nobel Prize winners and other worldwide leaders in precision medicine in presenting the latest research and application to patient care. Twelve people from the Rochester, Florida and Arizona campuses are featured speakers at the Individualized Medicine Lectures at the 10th International Society for Applied […]
Tags: #Dr. Grzegorz Nowakowski, #Dr. Jan Van Deursen, #Dr. Stanimir Vuk-Pavlovic, #Dr. Tamas Ordog, #Dr. William Faubion, #International Society for Applied Biological Sciences, #ISABS Conference, center for individualized medicine, Dr Nilüfer Ertekin-Taner, Dr. Eric Klee, Dr. George Vasmatzis, Dr. Gianrico Farrugia
November 23, 2016
Mayo Clinic investigators pinpoint cause, possible treatment for rare form of sarcoma
More than 12,000 Americans will be diagnosed with some type of soft tissue sarcoma this year. Sarcoma can be very difficult to treat, particularly when it has metastasized and spread to other parts of the body. Nearly 5,000 people will die from the disease this year, according to the American Cancer Society. New research from […]
Tags: #Dr. Aaron Mansfield, #inflammatory myofibroblastic tumors, #PrecisionMedicine, center for individualized medicine, Dr. George Vasmatzis, mayo clinic, sarcoma
October 11, 2016
New biomarker discovery approaches to improve patient care
Biomarkers are an important measure of health and disease that can help doctors understand how to more effectively treat cancerous tumors. The topic of TIGER-Bio, a new approach to biomarker discovery, came into the spotlight in a workshop on the final morning of Individualizing Medicine 2016: Advancing Care through Genomics, The session, TIGER-Bio: The Integrated […]
Tags: #3-D genomic models, #bomarker discovery, #Dr. Mark Truty, #Dr. Minetta Liu, #Dr. Mitesh Borad, #liquid biopsies, #xenograph models, Cancer Research, center for individualized medicine, DNA Sequencing, Dr. George Vasmatzis, Genomic Research
July 21, 2016
Liquid Biopsies Offer Hope for Earlier Treatment, Better Tracking of Ovarian Cancer
By Sharon Rosen
Ovarian cancer has long been one of the trickiest forms of cancer to diagnose and treat. It often goes unnoticed until the late stages. For most women, the cancer goes into remission after the first round of treatment but then returns with a vengeance. Three-quarters of the time, ovarian cancer comes back with a tumor […]
Tags: center for individualized medicine, diagnostic, Dr. George Vasmatzis, early detection for ovarian cancer, Liquid biopsy, mate-pair sequencing, mayo clinic, medical research, ovarian cancer, whole genome sequencing
January 22, 2016
Genomic Rearrangement Drives Pancreatic Cancer
By Jeff Briggs
Pancreatic cancer remains the fourth leading cause of cancer-associated deaths in the United States. While prognosis has improved for other major cancers thanks to early diagnosis, better therapies and a more comprehensive knowledge of genetic factors, death rates from pancreatic cancer continue to rise. Roughly 90 percent of pancreatic cancers are ductal pancreatic adenocarcinomas (PDAC) […]
Tags: biomarker, Biomarker Discovery Program, biomarkers, cancer, center for individualized medicine, Dr. George Vasmatzis, genomic medicine, NIH, Pancreatic Cancer
October 21, 2015
How Genomics Will Change the Way We Treat Cancer Patients
By Jeff Briggs
Dr. George Vasmatzis Brings Biomarker Discovery to New Audience at TEDxMinneapolis Everyone knows someone who has or has had cancer — including George Vasmatzis, Ph.D., co-director of the Biomarker Discovery Program at the Mayo Clinic Center for Individualized Medicine. This experience led him eventually to the Mayo Clinic where today he searches for clues in […]
Tags: biomarker, Biomarker Discovery Program, biomarkers, cancer, center for individualized medicine, Dr. George Vasmatzis, TED talks, TEDxMinneapolis