Items Tagged ‘Dr. Konstantinos Lazaridis’

November 30, 2020 · Leave a Comment

Mayo study shows gene sequencing, translational research improves diagnosis rates

By Colette Gallagher Colette Gallagher (@colettegallagher)

Many patients with unsolved medical mysteries often undergo genetic testing, but the tests do not always provide a conclusive diagnosis. The term “diagnostic odyssey” describes the series of clinical consultations and testing that patients with undiagnosed disorders often receive in search of a genetic diagnosis. To help these patients, Mayo Clinic researchers embarked on a […]

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Tags: diagnostic odyssey, Dr. Eric Klee, Dr. Konstantinos Lazaridis, gene sequencing, mayo clinic, Mayo Clinic Center for Individualized Medicine, translational omics


August 27, 2019 · Leave a Comment

Meet Margot Cousin, Ph.D.: Genetic detective, researcher, member of the A-team

By Sharon Rosen Sharon Rosen (@sharonhrosen)

When a young boy arrived at Mayo Clinic after repeatedly experiencing infections that caused a fever and a rapid loss of liver function, clinicians turned to genetic testing to find the cause of the illness. Margot Cousin, Ph.D., a translational genomics researcher in the Mayo Clinic Center for Individualized Medicine Translational Omics Program was among […]

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Tags: #liver cancer, acute liver failure, American Association for the Study oF Liver Disease, center for individualized medicine, Dr. Eric Klee, Dr. Konstantinos Lazaridis, Dr. Margot Cousin, Genetic Testing, genomics, Genomics Odyssey Board, individualized medicine, Liver disease


September 4, 2018 · Leave a Comment

Preemptive genetic testing: could it help you take charge of your health?

By Sharon Rosen Sharon Rosen (@sharonhrosen)

A blood pressure check, an immunization and a cholesterol test – these are all parts of your routine medical care. Someday, a genetic test to identify your risk for developing disease may also be added to the list. In fact, researchers believe that day is fast approaching thanks to the rapid advances in genomic medicine. […]

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Tags: #CIMCon18, #DNA sequencing tests, #Mayo Clinic Biobank, #pre-emptive genetic testing, center for individualized medicine, Dr. Konstantinos Lazaridis, Genetic Testing, mayo clinic, medical research, whole genome sequencing


January 2, 2018 · Leave a Comment

Finding individualized treatments in liver disease and beyond

By Sharon Rosen Sharon Rosen (@sharonhrosen)

In 1999, as a promising young physician-scientist, Konstantinos Lazaridis, M.D. was given an opportunity for additional research training as a Mayo Clinic Scholar. With the goal to establish an innovative, research program on liver disease in the Division of Gastroenterology and Hepatology his mentors suggested he make a choice between studying human genomics and hepatitis […]

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Tags: #Dr. Eric Lander, #family registry, #Mayo Clinic Clinomics Program, #PBC, #primary biliary cholangitis, #primary scleroscing cholangitis, #PSC, center for individualized medicine, Dr. Francis Collins, Dr. Konstantinos Lazaridis, Liver disease, mayo clinic


June 16, 2017 · Leave a Comment

Genetic testing helps guide diagnosis and treatment for digestive and liver diseases

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Many disorders of the digestive tract and liver can cause chronic, debilitating symptoms that begin in infancy or early childhood and require treatment to prevent the disease from progressing. Mayo Clinic is the first medical center to integrate genomic testing into personalized care plans for patients with some digestive and liver diseases. Researchers have discovered […]

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Tags: #Dr. Lisa Boardman, #Dr. Michael Stephens, #Gastroenterology and Hepatology Clinic, #gastrointestinal cancer, #gastrointestinal disorders, #gene panel testing, #Individualizing Medicine Clinic, #liver cancer, #medical resesarch, center for individualized medicine, Dr. Konstantinos Lazaridis, Genetic Testing


March 3, 2017 · Leave a Comment

Test reveals the right drug to help one patient manage panic attacks – finally

By Sharon Rosen Sharon Rosen (@sharonhrosen)

When it comes to medications, one size does not fit all. One of the areas where precision medicine has made the biggest impact is in developing tests to help physicians identify which medication will provide the greatest benefit and reduce harmful side effects for patients. Pharmacogenomics tests show how a patient’s genetic makeup impacts the […]

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Tags: #anti-anxiety medication, #drug-gene reactions, #primary scleroscing cholangitis, center for individualized medicine, Dr. Konstantinos Lazaridis, mayo clinic, medical research, PGx, pharmacogenomics


December 6, 2016 · Leave a Comment

Pharmacogenomics: the Rx for success

By Susan Buckles Susan Buckles (@susanbuckles)

Patients would save time, money and untold suffering if they proactively have DNA testing to match medications to their individual genetic profiles, writes Konstantinos Lazaridis, M.D., assistant director of Mayo Clinic Center for Individualized Medicine. It is likely not  uncommon for patients with a chronic medical condition to be on what he calls a “therapeutic […]

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Tags: #Center for Individualized Mediicne, #Genetic test results, #PrecisionMedicine, #RIGHT 10K study, DNA Testing, Dr. Konstantinos Lazaridis, mayo clinic, PGx, pharmacogenomics


October 18, 2016 · Leave a Comment

Embrace Pharmacogenomics in Your Practice

By Sharon Rosen Sharon Rosen (@sharonhrosen)

Article by Rachel Guibert, Public Affairs Currently, a population with a given disease generally receives the same therapy for all patients. Pharmacogenomics will change this ‘one-size-fits-all’ approach to drug treatments. Konstantinos Lazaridis, M.D., Eric Matey, Pharm.D., R.Ph., and Jeffrey Bishop, Pharm.D., M.S., B.C.P.P., are expecting a future practice reality in which clinicians will have every […]

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Tags: #Dr. Jeffrey Bishop, #drug-gene reactions, #preemptive pharmacogenomics, center for individualized medicine, Dr. Eric Matey, Dr. Konstantinos Lazaridis, mayo clinic, PGx, pharmacogenomics


April 1, 2016 · Leave a Comment

New Whole Exome Sequencing Plus Pharmacogenomics Test Now Available

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

  Regular visitors to the Center for Individualized Medicine blog know that whole exome sequencing and pharmacogenomics are frequent topics here.  Both are crucial elements in the Center’s commitment to and development of precision medicine.  Now we’re excited about bringing them together to provide patients with more individualized care and better answers to their health […]

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Tags: center for individualized medicine, Department of Clinical Genomics, DLMP, Dr. Konstantinos Lazaridis, Dr. Matthew Ferber, next generation sequencing, pharmacogenomics, Precision Medicine, whole exome sequencing, whole exome sequencing plus pharmacogenomics


March 7, 2016 · Leave a Comment

Whole-Exome Sequencing: A Rational Approach for ‘Diagnostic Odyssey’ Patients

By Jeff Briggs Jeff Briggs (@JeffreyBriggs)

A new clinical study from the Mayo Clinic Center for Individualized Medicine shows that whole-exome sequencing (WES) could serve as a viable diagnostic approach for identifying rare inherited diseases and providing a resolution for patients on a diagnostic odyssey.  WES is a laboratory process that determines, all at once, the entire unique DNA sequence (i.e., […]

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Tags: center for individualized medicine, Dr. Konstantinos Lazaridis, Individualized Medicine Clinic, IndividualizedMedicine, Mayo Clinic Proceedings, Precision Medicine, whole exome sequencing


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