Items Tagged ‘Dr. Matthew Goetz’

Novel data-driven approach for precision medicine

November 12, 2018

Novel data-driven approach for precision medicine

By Colette Gallagher colettegallagher

Thousands of patients’ tumors have been sequenced in the past decade, yielding a rich source of data on the changes associated with the cancer development and treatment response. However, there are no validated methods that are used in the clinic to select the best therapy. Today, Mayo Clinic researchers report an omics-guided (comprehensive) drug prioritization […]

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Tags: #Dr. Krishna Kalari, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Mayo Clinic Center for Individualized Medicine, personal genomics, pharmacogenomics


February 13, 2018

New international practice guidelines for using tamoxifen to treat breast cancer

By Colette Gallagher colettegallagher

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics. Tamoxifen is a hormonal agent used for the prevention and treatment of premenopausal and postmenopausal breast cancer that is estrogen receptor positive. […]

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Tags: #CIMCon18, #clinical guidelines, #Clinical Pharmacogenetics Implementation Consortium, #CYP2D6 geneotype, #estrogen receptor positive breast cancer, #tamoxifen, #targeted therapies, breast cancer, center for individualized medicine, DNA Sequencing, Dr. Matthew Goetz, Genetic Testing


November 30, 2017

3 ways Mayo Clinic is advancing individualized approaches to breast cancer treatment

By Sharon Rosen sharonhrosen

By Sharon Rosen and Susan Buckles Approximately one out of eight American women will develop breast cancer during their lifetime. In the U.S., it is estimated that more than 315,000 women will be diagnosed this year with breast cancer. While statistics show fewer women are dying from the disease, breast cancer still remains the second […]

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Tags: #blood tests, #breast cancer screening, #cancer detection, #cancer treatment, #Dr. Ciara O'Sullivan, #Dr. Minetta Liu, #genetic factors, #individualized therapy, #liquid biopsies, #xenografts, Beauty Study, breast cancer


May 19, 2017

Personalized care for aggressive breast cancers: 4 steps forward from the BEAUTY study

By Sharon Rosen sharonhrosen

Chemotherapy substantially reduces the chance that certain types of breast cancer will return or spread to other parts of the body and improves survival. Chemotherapy before surgery is a standard approach to treat women with aggressive breast cancer. However, chemotherapy does not shrink tumors in all women. Mayo Clinic researchers are turning to genomic sequencing […]

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Tags: #aggressive breast cancer, #chemotherapy-resistant cancer, #patient derived xenografts, #PDX, #personalized therapies, #xenografts, Beauty Study, biomarkers, breast cancer, center for individualized medicine, chemotherapy, DNA Sequencing


March 15, 2017

Mayo breast cancer study provides critical information on tumor sequencing and response to chemotherapy

By Sharon Rosen sharonhrosen

Article by Colette Gallagher, Public Affairs Mayo Clinic researchers reported in the Journal of the National Cancer Institute the results of the Breast Cancer Genome-Guided Therapy (BEAUTY) study designed to help researchers and physicians better understand why current standard chemotherapy stops breast cancer in some women but fails in others. Tumor sequencing is increasingly used to select […]

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Tags: #Breast Cancer Genome-Guided Therapy study, #DNA sequencing tests, #Journal of the National Cancer Institute, #tumor sequencing, breast cancer, center for individualized medicine, chemotherapy, Dr. Judy Boughey, Dr. Matthew Goetz, mayo clinic, Mayo Clinic Cancer Center, medical research


July 7, 2016

Mayo Clinic Researcher Receives Distinguished Award for Pharmacogenomics Research

By Sharon Rosen sharonhrosen

Liewei Wang, M.D., Ph.D., Mayo Clinic professor of Pharmacology, received the highly prestigious Leon I. Goldberg Early Investigator Award for her pharmacogenomics research. Pharmacogenomics is the study of how a patient’s genes affect the body’s response to medication. She is the second Mayo Clinic faculty member to have received the award by the American Society for […]

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Tags: American Society for Clinical Pharmacology and Therapeutics, biomarkers, center for individualized medicine, Dr. James Ingle, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Dr. Richard Weinshilboum, Leon I. Goldberg Early Investigator Award, mayo clinic, Mayo Clinic Center for Individualized Medicine, pharmacogenomics


October 26, 2015

Tailoring Treatment, One Cancer Patient at a Time

By Jeff Briggs JeffreyBriggs

This post was originally published last week on Footnote, a website that brings academic research and ideas to a broader audience, as part of a three-part series on how precision medicine is being used today to improve health care treatment for patients. The first article in the series, “Genomics Moves From The Lab To The […]

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Tags: BEAUTY, beauty project, BRCA1, BRCA2, breast cancer, center for individualized medicine, Dr. Judy Boughey, Dr. Matthew Goetz, Holly Boehle, individualized medicine, Precision Medicine


August 4, 2015

Breast Cancer Research Funded One Hair Cut at a Time

By Jeff Briggs JeffreyBriggs

Breast cancer touches everyone. One out of every eight women will be diagnosed at some time in her life with the disease. Every one of them is somebody’s mother, daughter, grandmother or niece. Every one of them has family and friends. In all, over 2.8 million women in the U.S. have a history of or […]

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Tags: BEAUTY, beauty project, breast cancer, cancer, center for individualized medicine, Clip for the Cure, Dr. Judy Boughey, Dr. Matthew Goetz, Regis Foundation, Regis Foundation for Breast Cancer Research


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