March 19, 2021
Lack of diversity in genomic databases may affect therapy selection for minority groups
Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology. The researchers investigated the use of genomic databases and found that tumor mutation burden was significantly inflated in Black patients compared to White patients. As a […]
Tags: #Dr. Aaron Mansfield, #Dr. Mitesh Borad, #Dr. Yan Asmann, Dr. Alex Adjei, Dr. Leif Bergsagel, mayo clinic
May 7, 2019
Targeting bile duct cancer – meet Mitesh Borad, M.D.
By Sharon Rosen
The search for treatment targets for patients with bile duct cancer, also known as cholangiocarcinoma, has taken a 360 degree turn, offering new hope for patients. That’s according to Mitesh Borad, M.D., deputy director for Center for Individualized Medicine Biomarker Discovery Program at Mayo Clinic’s Arizona campus, Dr. Borad and his colleagues are using new […]
Tags: #Dr. Mitesh Borad, #liver cancer, #targeted therapies, bile duct cancer, Biomarker Discovery Program, cholangiocarcinoma, fibroblast growth factor receptor (FGFR) inhibitors, Genetic Testing, genomics, Liquid biopsy, mayo clinic, Mayo Clinic Center for Individualized Medicine
November 7, 2017
Twenty-first century precision medicine cancer care
By Sharon Rosen
As genomic sequencing has become faster and less expensive, physicians have used this new technology to guide and manage care for patients with cancer. Genomic testing, also known as genomic profiling, was initially used for patients with advanced cancer when standard therapy failed. The goal of the testing was to identify unique genetic characteristics of […]
Tags: #cancer treatment, #Dr. Mitesh Borad, #genetic panel tests, #Genomic profiling, #targeted therapies, #tissue biopsy, #tumor sequencing, cancer, center for individualized medicine, Dr. Patricia LoRusso, mayo clinic, Mayo Clinic Proceedings
September 25, 2017
Study evaluates effectiveness of deep genomic profiling in clinical setting
Genomic profiling is used today for patients with advanced cancers to help develop new ways to diagnose and treat their disease and offer an individualized treatment plan. While gene panel testing is relatively commonplace, there are many barriers to using new and more sophisticated DNA technologies. According to Mitesh Borad, M.D., an oncologist at the […]
Tags: #cancer treatment, #CIMCon17, #Dr. Mitesh Borad, #genetic profiling, #Individualizing Medicine 2017, #long-insert whole genome, #Nature scientific Reports, #targeted therapies, #whole transcriptome sequencing, Advanced Cancer, center for individualized medicine, mayo clinic
October 11, 2016
New biomarker discovery approaches to improve patient care
Biomarkers are an important measure of health and disease that can help doctors understand how to more effectively treat cancerous tumors. The topic of TIGER-Bio, a new approach to biomarker discovery, came into the spotlight in a workshop on the final morning of Individualizing Medicine 2016: Advancing Care through Genomics, The session, TIGER-Bio: The Integrated […]
Tags: #3-D genomic models, #bomarker discovery, #Dr. Mark Truty, #Dr. Minetta Liu, #Dr. Mitesh Borad, #liquid biopsies, #xenograph models, Cancer Research, center for individualized medicine, DNA Sequencing, Dr. George Vasmatzis, Genomic Research