Items Tagged ‘#drug-gene interactions’

November 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen sharonhrosen

Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]

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Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine


June 21, 2018

Taking action: using pharmacogenomics testing to individualize care for colorectal cancer

By Sharon Rosen sharonhrosen

Every day, Pashtoon Kasi, M.D., M.B.B.S. is inspired by his patients with colorectal cancer to deliver the best, individualized care to meet their unique needs. As an oncologist at Mayo Clinic’s campus in Florida, Dr. Kasi is seeing many of the growing number of younger patients – those in their 20’s, 30’s and 40’s – diagnosed with […]

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Tags: #CIMCon18, #clinical research, #drug-gene interactions, #Individualizing Medicine 2018, #medication side effects, #pharmacogenomics testing, #pre-emptive pharmacogenomics testing, center for individualized medicine, chemotherapy, colorectal cancer, Genetic Testing, mayo clinic


March 20, 2018

Mayo’s RIGHT 10K – moving pharmacogenomics into everyday clinical practice

By Sharon Rosen sharonhrosen

After nearly half a century of research, Mayo Clinic is a leader in moving pharmacogenomics into clinical practice. This year pharmacogenomics test results for 10,000 Mayo Clinic patients, all participants in the RIGHT 10K study, are being added to the electronic health record. “I’ve spent my career exploring pharmacogenomics – how a person’s genetics affect […]

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Tags: #CIMCon18, #DNA sequencing tests, #Dr. Paul Takahashi, #drug-gene interactions, #pharmacogenomic testing, #RIGHT 10K, center for individualized medicine, DNA, Dr. Richard Weinshilboum, genomics, mayo clinic, medical research


November 28, 2017

From pharmacogenomics to pharmaco-omics – individualized care for every patient

By Sharon Rosen sharonhrosen

When prescribing a medication for you, your physician considers many factors, including your age, sex, weight and current health conditions. Now, add to that list your unique genetic characteristics. Your genes affect the way you respond to medications. Pharmacogenomics is a term used to describe the use of genomic information to help select the right […]

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Tags: #drug-gene interactions, #pharmacogenomics testing, #RIGHT 10K study, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, individualized medicine, mayo clinic, Mayo Clinic Proceedings, pharmacogenomics


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