Items Tagged ‘#drug-gene interactions’

July 9, 2019

Mayo experts provide insights into how genes affect medication response

By Sharon Rosen Sharon Rosen

Pharmacogenomics – how a person’s genes affect medication response – is touching virtually every area of medical care.  Findings from the Mayo Clinic RIGHT study (Right Drug, Right Dose, Right Time–Using Genomic Data to Individualize Treatment) showed that 99% of participants had at least one genetic variant that may affect their response to medications.    […]

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Tags: #addiction, #anti-seizure medication, #Center for Individualized Mediicine, #Dr. Lauren Cornell, #Dr. Sanjay Bagaria, #Dr. William Freeman, #Dr. William Palmer, #drug-gene interactions, #epilepsy, #estrogen receptor positive breast cancer, #medical education, #neurological diseases


June 17, 2019

Considering a DNA test? Helpful tips before you take the plunge

By Sharon Rosen Sharon Rosen

Article by Shannon Wieloch The availability of genetic testing has exploded. You hear about it on television, the radio and the internet. Family members are verifying age-old stories of their ancestry. Co-workers are talking about the genes that predispose them to weigh 12% less than average. With everyone doing it, a consumer may think, “Well, […]

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Tags: #direct-to-consumer genetic testing, #disease risk, #drug-gene interactions, carrier screening, center for individualized medicine, data privacy, diagnostic tests, Genetic Testing, mayo clinic, Mayo Clinic GeneGuide


November 5, 2018

Pharmacogenomics: finding the right drug, dose for cancer therapy

By Sharon Rosen Sharon Rosen

Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]

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Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine


June 21, 2018

Taking action: using pharmacogenomics testing to individualize care for colorectal cancer

By Sharon Rosen Sharon Rosen

Every day, Pashtoon Kasi, M.D., M.B.B.S. is inspired by his patients with colorectal cancer to deliver the best, individualized care to meet their unique needs. As an oncologist at Mayo Clinic’s campus in Florida, Dr. Kasi is seeing many of the growing number of younger patients – those in their 20’s, 30’s and 40’s – diagnosed with […]

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Tags: #CIMCon18, #clinical research, #drug-gene interactions, #Individualizing Medicine 2018, #medication side effects, #pharmacogenomics testing, #pre-emptive pharmacogenomics testing, center for individualized medicine, chemotherapy, colorectal cancer, Genetic Testing, mayo clinic


March 20, 2018

Mayo’s RIGHT 10K – moving pharmacogenomics into everyday clinical practice

By Sharon Rosen Sharon Rosen

After nearly half a century of research, Mayo Clinic is a leader in moving pharmacogenomics into clinical practice. This year pharmacogenomics test results for 10,000 Mayo Clinic patients, all participants in the RIGHT 10K study, are being added to the electronic health record. “I’ve spent my career exploring pharmacogenomics – how a person’s genetics affect […]

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Tags: #CIMCon18, #DNA sequencing tests, #Dr. Paul Takahashi, #drug-gene interactions, #pharmacogenomic testing, #RIGHT 10K, center for individualized medicine, DNA, Dr. Richard Weinshilboum, genomics, mayo clinic, medical research


November 28, 2017

From pharmacogenomics to pharmaco-omics – individualized care for every patient

By Sharon Rosen Sharon Rosen

When prescribing a medication for you, your physician considers many factors, including your age, sex, weight and current health conditions. Now, add to that list your unique genetic characteristics. Your genes affect the way you respond to medications. Pharmacogenomics is a term used to describe the use of genomic information to help select the right […]

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Tags: #drug-gene interactions, #pharmacogenomics testing, #RIGHT 10K study, center for individualized medicine, Dr. Liewei Wang, Dr. Richard Weinshilboum, individualized medicine, mayo clinic, Mayo Clinic Proceedings, pharmacogenomics


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