Items Tagged ‘Epigenomics’

March 5, 2020

Rise in kidney cancer spurs Mayo researcher’s urgency to improve patient outcomes

By Barbara J. Toman Barbara J. Toman

As a trainee oncologist, Thai Ho, M.D., Ph.D., was struck by the number of people he saw at a veterans’ hospital with kidney cancer. “It’s one of the cancers that disproportionately affects military personnel, possibly due to environmental exposures,” he says. The results can be devastating. “On average, patients with kidney cancer lose 12 years […]

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Tags: cancer, Cancer Research, Epigenetic research, Epigenomics, kidney cancer, Research


February 20, 2020

Mayo researchers’ endometrial cancer discovery could lead to window of opportunity for prevention

By Susan Murphy Susan Murphy

What if a doctor could alert a woman a year or more in advance that she is likely to develop endometrial cancer? Researchers at Mayo Clinic Center for Individualized Medicine have found evidence linking functional modification of certain genes to the emergence of the disease, providing a novel opportunity for intervention and prevention. The new […]

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Tags: #endometrial biopsy, cancer, Cancer Research, Endometrial cancer, Epigenetic research, Epigenomics


February 11, 2020

7 ways Mayo Clinic is leading to cure, connect and transform health care

By Susan Murphy Susan Murphy

  Mayo Clinic Center for Individualized Medicine’s physicians and researchers are leading the way to cure, connect and transform health care by combining their expertise to solve serious or complex medical conditions. Here are seven innovative ways the Center’s investigators are working together to provide patients with answers, treatment options and optimism.   Cultivating cutting-edge […]

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Tags: Biobank, cancer, cancer genomics, Epigenomics, Genomic Sequencing, infections, microbiome, rare disease


January 6, 2020

“I Just Didn’t Understand”: On a Mission to Cure ALS

By Barbara J. Toman Barbara J. Toman

For Veronique Belzil, Ph.D., the fight against amyotrophic lateral sclerosis (ALS) is personal. In 2000, while working as a psychologist in Canada, she watched her husband’s uncle succumb to the disease. “The progression was so fast and his condition was so sad,” she says. “I just didn’t understand how this could happen.” That’s a common […]

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Tags: #Mayo Clinic Center for Individualized Medicine Epigenomics Program, ALS, amyotrophic lateral sclerosis, center for individualized medicine, Epigenomics, Lou Gehrig's disease, mayo clinic, neurodegenerative disorders, Veronique Belzil


February 4, 2019

Meet Chuanhe Yu, Ph.D.: searching for the genetic switches linked to disease

By Sharon Rosen Sharon Rosen

Chuanhe Yu, Ph.D. has always had an interest in genetics – the thousands of genes that make each of us unique. His research focuses on the growing field of epigenetics, which aims to better understand how environmental and lifestyle factors cause chain reactions, flipping the switch on genes and the  instructions they provide to guide […]

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Tags: #cancer biology, #cell biology, #DNA replication, #Dr. Chuanhe Yu, #epigenetics, #epigenome, #eSPAN model, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, cancer, center for individualized medicine, Epigenomics, mayo clinic


July 30, 2018

Tool of the trade: researcher applies artificial intelligence to uncover causes, risks for disease

By Sharon Rosen Sharon Rosen

Some diseases, such as certain breast and colon cancers, are linked to genetic mutations passed down in families. But for many other diseases there are no direct genetic links that explain why the disease develops. That’s why Manolis Kellis, Ph.D. and his team are using artificial intelligence to uncover the hidden cause of disease. Dr. […]

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Tags: #CIMCon18, #computational genetics, #Dr. Manolis Kellis, #Dr. Tamas Ordog, #Individualizing Medicine 2018, #Massachusetts Institute of Technology, #mathematical models, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, #MIT Computational Biology Group, #obesity, Alzheimer’s disease, center for individualized medicine


July 7, 2017

Educating the next generation of innovators to usher in the genomic age of medicine

By Sharon Rosen Sharon Rosen

By Susan Buckles Bright and eager minds are being primed to tackle the big data challenge that comes with genomic medicine. The Computational Genomics class, a collaboration between Mayo Clinic and the University of Illinois at Urbana Champaign (Illinois), is aimed at developing a workforce with skills to more quickly, cheaply, and efficiently analyze, interpret, […]

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Tags: #Biostatistics, #genetic data analysis, #Genomic analysis, #Mayo Clinic & Illinois Alliance for Technology-based Healthcare, #Mayo-Illinois Computational Genomics Course, Bioinformatics, center for individualized medicine, DNA Sequencing, Epigenomics, Genomic Sequencing, mayo clinic, medical research


August 9, 2016

Paper Published in Science Explores How a Genetic Mutation Causes Tumor Growth

By Sharon Rosen Sharon Rosen

Article by Colette Rector, Public Affairs New research is shedding light on how a rare bone tumor develops. Zhiguo Zhang, Ph.D., a researcher at the Mayo Clinic Center for Individualized Medicine, studied how a mutation contributes to bone tumor growth by impacting the epigenome — a series of chemical modifications that change how genes are […]

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Tags: #bone tumor, #CIMCon16, #Dr. Jennifer Westendorf, #Dr. Zhiguo Zhang, #Science Magazine, center for individualized medicine, Epigenomics, gene editing, mayo clinic


June 14, 2016

Abstract Deadline Fast Approaching for Individualizing Medicine Conference 2016

By Jeff Briggs Jeff Briggs

Okay, you’re probably still noodling out the final details of that great idea you have for the poster session on epigenomics or pharmacogenomics or microbiome.  Or did the big news about Mayo Clinic and the Center for Individualized Medicine being selected by the National Institutes of Health to serve as the national Precision Medicine Initiative […]

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Tags: #CIMCon16, Biobank, center for individualized medicine, Epigenomics, genomics, individualized medicine, Individualized Medicine Conference 2016, microbiome, NIH, pharmacogenomics, Precision Medicine


March 3, 2016

Individualizing Medicine Conference 2016: Mark Your Calendars for October 5–6

By Jeff Briggs Jeff Briggs

Time off, travel plans, hotel reservations. These things don’t happen at the last minute. If you’re interested in genomic medicine and how precision medicine is being applied in health care today, you should be planning now to join us at Mayo Clinic in Rochester, Minn., for the 2016 Individualizing Medicine Conference. The dates are October […]

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Tags: #CIMCon2016, Biomarker Discovery, cancer, center for individualized medicine, DNA Sequencing, Epigenomics, genomic medicine, individualized medicine, individualizing medicine conference, individualizing medicine conference 2016, microbiome, pharmacogenomics


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