January 8, 2016
Foreseeing the Future of Vaccines
By Jeff Briggs
Is there a new “omics” coming to health care? Here at the Mayo Clinic Center for Individualized Medicine we have epigenomics and pharmacogenomics. We have clinomics, and faithful readers of this blog know we love discussing genomics. Now, doctors at Mayo Clinic are pioneering a new field of research called vaccinomics. Their hope is to […]
Tags: center for individualized medicine, Clinomics, Dr Greg Poland, Epigenomics, individualized medicine, mayo clinic, Mayo Clinic's Vaccine Research Group, pharmacogenomics, vaccinomics
September 25, 2015
Individualizing Medicine 2015 Comes to an End
By Jeff Briggs
Over 800 people from 31 states and 10 countries attended this year’s Individualizing Medicine Conference: From Promise to Practice. They heard presentations from over 125 experts about how individualized medicine can fulfill the promise of moving from the laboratory bench of the research to the bedside of the patient. After an opening symposium for the […]
Tags: cancer, center for individualized medicine, Dr. J. Craig Venter, Epigenomics, Gianrico Farrugia, individualized medicine, pharmacogenomics, Precision Medicine
September 11, 2015
By Jeff Briggs
An old friend is returning to Rochester, Minn., site of the Mayo Clinic Center for Individualized Medicine’s fourth annual conference on genomic medicine. Gianrico Farrugia, M.D., the former director of the center, and now vice president of Mayo Clinic and CEO of Mayo Clinic in Florida, will return to his roots in southeast Minnesota to […]
Tags: biomarker, center for individualized medicine, Epigenomics, genomics, Gianrico Farrugia, individualized medicine, Individualized Medicine Conference 2015, microbiome, personalized medicine, pharmacogenomics, Precision Medicine
September 9, 2015
Mayo Clinic Team Shares Comparison of Sequencing, Array Methods for DNA Methylation Profiling
By Jeff Briggs
What are the biological mechanisms that switch genes on and off? Think of it like this: In identical twins, why does one twin develop cancer or rheumatoid arthritis or diabetes and the other doesn’t? Their DNA is exactly the same. That’s epigenomics at play. While the DNA is the same, the network of chemical switches […]
Tags: center for individualized medicine, DNA methylation, DNA Testing, Dr. Julie Cunningham, Epigenetic research, Epigenomics
May 6, 2015
What Is Epigenomics And How Is It Helping in the Fight Against Cancer?
By Jeff Briggs
How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow, and what illnesses they acquire as they age? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mold that […]
Tags: cancer, center for individualized medicine, DNA, DNA Sequencing, Epigenomics, individualized medicine, Precision Medicine
May 15, 2014
By AJ Montpetit
Research from the Epigenomics Program was recently published, in coordination with the Gastroenterology Research Unit, Departments of Biochemistry and Molecular Biology, Physiology and Biophysics, and Medicine, focusing on the KLF14 gene, which has elicited attention as master regulator of lipid metabolism. Sphingosine kinase 1 (SK1) is an FGF-inducible gene responsible for generation of sphingosine-1-phosphate, […]
Tags: dna test, DNA Testing, Epigenomics, gene sequencing, genome science, genomic medicine, genomics, individualized medicine, personal genomics, personalized medicine, predictive medicine
March 18, 2014
Individualized Medicine 101: Epigenomics
For patients who exhaust all traditional cancer therapies, pinpointing new molecular targets for therapy requires that we examine not only the differences between their “normal” DNA and the mutated DNA of their tumor, but also other factors that influence how genes are expressed. These “other factors” are proteins that chemically modify either the […]
Tags: dna test, DNA Testing, Epigenomics, gene sequencing, genome science, genomic medicine, genomics, individualized medicine, personal genomics, personalized medicine, predictive medicine
January 2, 2014
Eric Schmidt, Google Chairman, Sees Genetics as “Unfathomably Important”
Not one to shy from giving bold predictions, Google Chairman and Mayo Clinic Trustee Eric Schmidt sat down with Bloomberg TV to talk on trends to watch for in 2014. One area of interest was the ability to have your personal genomic sequence available to you. The trove of medically relevant information stored in your […]
Tags: biomarker, Clinomics, DNA Sequencing, Epigenomics, Eric Schmidt, Genetics, Genome Sequencing, genomics, Google, individualized medicine, microbiome, personalized care