Items Tagged ‘gene sequencing’
November 30, 2020
Mayo study shows gene sequencing, translational research improves diagnosis rates
Many patients with unsolved medical mysteries often undergo genetic testing, but the tests do not always provide a conclusive diagnosis. The term “diagnostic odyssey” describes the series of clinical consultations and testing that patients with undiagnosed disorders often receive in search of a genetic diagnosis. To help these patients, Mayo Clinic researchers embarked on a […]
Tags: diagnostic odyssey, Dr. Eric Klee, Dr. Konstantinos Lazaridis, gene sequencing, mayo clinic, Mayo Clinic Center for Individualized Medicine, translational omics
December 30, 2019
In Florida, a powerhouse of cancer research
By Susan Murphy 
By Sara Nick The Mayo Clinic Cancer Center, which spans Mayo Clinic’s Arizona, Florida and Minnesota locations, has 10 distinct research programs funded by the National Cancer Institute that are centered on broad areas such as immunology and gene therapy, or specific tumor types such as brain and gastrointestinal. Each research topic is treated with a multidisciplinary approach that ties together science, clinical relevance […]
Tags: #gastrointestinal cancer, cancer, Cancer Research, gene sequencing, immunology
April 15, 2016
5 Things You Need to Know about Genetic Testing
By Jeff Briggs 
When you provide just one sample of your DNA, researchers are able to use it to learn more about your health history, assess your chances of contracting certain diseases and even gain a better understanding of the importance family history can play in your health outlook. It sounds futuristic, but it is all very real. […]
Tags: Bioethics, center for individualized medicine, DNA Sequencing, Dr. Richard Sharp, gene sequencing, Genetic Testing, Genome Sequencing
February 11, 2016
Next-Generation Sequencing: Targeted Panels Versus Whole Exome Sequencing
By Jeff Briggs
Next-generation sequencing is becoming more prominent in the clinical laboratory, something we reported on recently on the Center for Individualized Medicine blog. With its unprecedented throughput, scalability, and speed, next-generation sequencing enables researchers to study biological systems at a level never before possible. Today’s complex genomic research questions demand a depth of information beyond […]
Tags: center for individualized medicine, DNA, DNA Sequencing, Dr. Brian Dawson, Dr. Eric Klee, Dr. Matthew Ferber, gene sequencing, mayo medical laboratories, MML, next generation sequencing, whole exome sequencing
July 16, 2015
Test for Diagnosing Fibrolamellar Carcinoma Yields 100-Percent Accuracy
By Jeff Briggs
A fusion gene is a hybrid gene formed from two previously separate genes. It can occur as a result of translocation, interstitial deletion or chromosomal inversion. Known to scientists since 1960, fusion genes can contribute to tumor formation because fusion genes can produce much more active abnormal protein than non-fusion genes. Often, fusion genes are […]
Tags: cancer, center for individualized medicine, Dr. Rondell Graham, Fibrolamellar Carcinoma, gene sequencing, Genetic Testing, Precision Medicine
February 18, 2015
Biobanking and Precision Medicine
By Center for Individualized Medicine 
Mayo Clinic is excited about the national focus on individualized medicine and what the future holds. More than half ($130 million) of the total $215 million budget request, put forth by President Obama’s Precision Medicine Initiative, is for a national biobanking initiative that draws on existing collections across the country. Mayo Clinic has among […]
Tags: biomarker, biomarkers, cancer, center for individualized medicine, DNA, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing
February 10, 2015
Building a National Cohort for Precision Medicine
By Center for Individualized Medicine
With the State of the Union announcement of the $215 Million Precision Medicine Initiative, one of the most exciting aspects of the Initiative was the call for a national cohort for research and genomic sequencing. The National Institutes of Health (NIH) will be hosting a two-day workshop starting tomorrow, February 11th, of which […]
Tags: center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science, Genome Sequencing, Genomic
January 30, 2015
National Unveiling of Precision Medicine Initiative
By Center for Individualized Medicine
Former Medical Director of the Center for Individualized Clinic, Gianrico Farrugia, is currently in the East Room of the White House awaiting the unveiling of the Precision Medicine Initiative. Mayo Clinic is excited about the national focus on individualized medicine, and what the future holds with this $215 million investment. The Precision Medicine Initiative […]
Tags: center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science, Genome Sequencing, Genomic
January 28, 2015
How the President’s Precision Medicine Plan Might Help You
By Center for Individualized Medicine
Article Originally Feature on Washington Post by Lenny Bernstein In his hour-long State of the Union address Tuesday night, President Obama spent a few seconds announcing a “Precision Medicine Initiative,” but did little to explain what he has in mind. Background materials distributed by the White House show that Obama wants to […]
Tags: center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, Genomic, genomic medicine
January 26, 2015
New Exam For Dense Breast Tissue Nearly Quadruple Detection For Invasive Breast Cancers
By Center for Individualized Medicine
A new breast imaging technique pioneered at Mayo Clinic nearly quadruples detection rates of invasive breast cancers in women with dense breast tissue, according to the results of a major study published this week in the American Journal of Roentgenology. Molecular Breast Imaging (MBI) is a supplemental imaging technology designed to find tumors that […]
Tags: breast cancer, cancer, center for individualized medicine, Dense Breast, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science