Items Tagged ‘gene sequencing’
April 19, 2022
Iftikhar Kullo, M.D. to serve on National Advisory Council on Human Genome Research
Iftikhar Kullo, MD., has been invited to serve on the National Advisory Council on Human Genome Research (NACHGR) of the National Institutes of Health (NIH), by the Hon’ble Xavier Becerra, Secretary of the Department of Health and Human Services (DHHS), for a term beginning immediately and ending September 30, 2024. The Council advises the DHHS, the […]
Tags: center for individualized medicine, DNA Testing, Dr. Iftikhar Kullo, gene sequencing, Genetics, genomics, individualized medicine, medical research
March 31, 2022
Mayo Clinic patient grateful after genetic test leads to unexpected, early detection of colon cancer
By Susan Murphy 
Alejandro Mirazo, 56, never imagined his genetic test results would reveal a hereditary link to cancer, or that his findings would potentially save his life. He had participated in a preemptive DNA research sequencing study for Mayo Clinic’s Center for Individualized Medicine in fall 2021 solely to contribute to medical research. As a Mexican American, he also wanted to add diversity to Mayo Clinic’s genomic dataset.
Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, medical research, personalized medicine
March 24, 2022
What you should know about genetics, colorectal cancer
By Susan Murphy
By Nicole Brudos Ferrara Colorectal cancer begins when healthy cells in the colon or rectum develop mutations, or changes, in their DNA. These damaged cells then become cancerous, grow and divide uncontrollably, and form a tumor. Genetic factors play a role in this process. Some gene mutations passed through generations of your family can increase […]
Tags: center for individualized medicine, colon cancer, DNA Testing, Dr. Niloy "Jewel" Samadder, gene sequencing, Genetics, genomic medicine, hereditary colon cancer
December 28, 2021
10 Significant Mayo Clinic Center for Individualized Medicine studies of 2021
By Susan Murphy
It has been an impactful year of genomic and multi-omic research and scientific discoveries in Mayo Clinic’s Center for Individualized Medicine. While much focus in 2021 was centered on advancing the knowledge of COVID-19, Mayo scientists and physician have also worked to develop individualized treatments, prevention measures and diagnostics for patients with rare and undiagnosed diseases, cancer and other illnesses.
Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, genomics
November 30, 2020
Mayo study shows gene sequencing, translational research improves diagnosis rates
Many patients with unsolved medical mysteries often undergo genetic testing, but the tests do not always provide a conclusive diagnosis. The term “diagnostic odyssey” describes the series of clinical consultations and testing that patients with undiagnosed disorders often receive in search of a genetic diagnosis. To help these patients, Mayo Clinic researchers embarked on a […]
Tags: diagnostic odyssey, Dr. Eric Klee, Dr. Konstantinos Lazaridis, gene sequencing, mayo clinic, Mayo Clinic Center for Individualized Medicine, translational omics
December 30, 2019
In Florida, a powerhouse of cancer research
By Susan Murphy
By Sara Nick The Mayo Clinic Cancer Center, which spans Mayo Clinic’s Arizona, Florida and Minnesota locations, has 10 distinct research programs funded by the National Cancer Institute that are centered on broad areas such as immunology and gene therapy, or specific tumor types such as brain and gastrointestinal. Each research topic is treated with a multidisciplinary approach that ties together science, clinical relevance […]
Tags: #gastrointestinal cancer, cancer, Cancer Research, gene sequencing, immunology
April 15, 2016
5 Things You Need to Know about Genetic Testing
By Jeff Briggs 
When you provide just one sample of your DNA, researchers are able to use it to learn more about your health history, assess your chances of contracting certain diseases and even gain a better understanding of the importance family history can play in your health outlook. It sounds futuristic, but it is all very real. […]
Tags: Bioethics, center for individualized medicine, DNA Sequencing, Dr. Richard Sharp, gene sequencing, Genetic Testing, Genome Sequencing
February 11, 2016
Next-Generation Sequencing: Targeted Panels Versus Whole Exome Sequencing
By Jeff Briggs
Next-generation sequencing is becoming more prominent in the clinical laboratory, something we reported on recently on the Center for Individualized Medicine blog. With its unprecedented throughput, scalability, and speed, next-generation sequencing enables researchers to study biological systems at a level never before possible. Today’s complex genomic research questions demand a depth of information beyond […]
Tags: center for individualized medicine, DNA, DNA Sequencing, Dr. Brian Dawson, Dr. Eric Klee, Dr. Matthew Ferber, gene sequencing, mayo medical laboratories, MML, next generation sequencing, whole exome sequencing
July 16, 2015
Test for Diagnosing Fibrolamellar Carcinoma Yields 100-Percent Accuracy
By Jeff Briggs
A fusion gene is a hybrid gene formed from two previously separate genes. It can occur as a result of translocation, interstitial deletion or chromosomal inversion. Known to scientists since 1960, fusion genes can contribute to tumor formation because fusion genes can produce much more active abnormal protein than non-fusion genes. Often, fusion genes are […]
Tags: cancer, center for individualized medicine, Dr. Rondell Graham, Fibrolamellar Carcinoma, gene sequencing, Genetic Testing, Precision Medicine
February 18, 2015
Biobanking and Precision Medicine
By Center for Individualized Medicine 
Mayo Clinic is excited about the national focus on individualized medicine and what the future holds. More than half ($130 million) of the total $215 million budget request, put forth by President Obama’s Precision Medicine Initiative, is for a national biobanking initiative that draws on existing collections across the country. Mayo Clinic has among […]
Tags: biomarker, biomarkers, cancer, center for individualized medicine, DNA, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing