Items Tagged ‘Genetics’

February 8, 2021

Mayo Clinic algorithm shows potential in individualizing treatment for depression

By Susan Murphy Susan Murphy (@susanmurphy)

Finding an effective antidepressant medication for people diagnosed with depression, also called major depressive disorder, is often a long and complex process of “try and try again” ― going from one prescription to the next until achieving a therapeutic response. This complex disease, which affects more than 16 million people in the U.S., can cause […]

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Tags: #algorithm, artificial intelligence, depression, Genetics, major depressive disorder


January 28, 2021

First hybrid gene therapy shows early promise in treating long QT syndrome

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. Researchers demonstrated its potential therapeutic efficacy in two in vitro model systems using beating heart cells reengineered from the blood samples of patients with type […]

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Tags: #Dr. Michael Ackerman, #gene therapy, #News release, Circulation, congenital heart disease, Genetics, long QT syndrome, mayo clinic, Mayo Clinic Center for Individualized Medicine, Minnesota News Releases


January 19, 2021

Mayo researchers explore genetics behind COVID-19 outcomes

By Susan Murphy Susan Murphy (@susanmurphy)

Some patients with COVID-19 experience severe complications, such as organ damage, shortness of breath, neurological impairment and chronic fatigue. A team of researchers within Mayo Clinic Center for Individualized Medicine is contributing to the global effort of using advanced genetic sequencing to find out which genes influence disease outcomes. “Our findings will be crucial in […]

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Tags: covid-19, Genetic Testing, Genetics, Genomic Research, individualized medicine, Research


December 24, 2020

2020 Mayo Clinic Precision Medicine Advances

By Susan Murphy Susan Murphy (@susanmurphy)

This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]

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Tags: artificial intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research


November 23, 2020 · Leave a Comment

Diversifying genomic medicine beyond genes

By Colette Gallagher Colette Gallagher (@colettegallagher)

The work to improve health and health care is ongoing and ever-evolving. It takes many shapes, from streamlining delivery to improving care and pursuing inclusive medical research to help develop precision medicine for all populations. This was a key element of the Arizona Return of Actionable Variants Empirical, or RAVE, study, which brought genomic medicine to […]

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Tags: Arizona State University, Dr. Iftikhar Kullo, Dr. Richard Sharp, eMERGE Network, Genetics, mayo clinic, Mayo Clinic Center for Individualized Medicine, Mountain Park Health Center


November 2, 2020 · Leave a Comment

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations

By Susan Murphy Susan Murphy (@susanmurphy)

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. In a new study published in JAMA Oncology, scientists with Mayo Clinic’s Center for Individualized Medicine conducted genetic testing in more than 3,000 patients who were diagnosed with cancer […]

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Tags: cancer genomics, Cancer Research, Genetic Testing, Genetics, Individualizing Medicine, Inherited cancer, Research


September 10, 2020

Mayo Clinic researcher finds potential target to control rare genetic disease that strikes in teen years

By Susan Murphy Susan Murphy (@susanmurphy)

Patients with a rare genetic disease called familial adenomatous polyposis, (FAP), often face debilitating challenges. Typically striking in the early teenage years, FAP is characterized by hundreds to thousands of tiny polyps forming in the colon and rectum and leading to a nearly 100% percent likelihood that they will get colon cancer without a life-altering […]

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Tags: Genetic Testing, Genetics, hereditary cancer, hereditary colon cancer, individualized medicine


July 1, 2020 · Leave a Comment

Mayo researchers earn NIH award to study use of genetic risk scores for heart disease in diverse populations

By Susan Murphy Susan Murphy (@susanmurphy)

In recognition of their high impact work of advancing the field of genetic risk profiling for disease risk stratification, the National Institutes of Health (NIH) has awarded Mayo Clinic researchers Iftikhar Kullo, M.D. and Richard Sharp Ph.D. part of $75 million in funding over five years to improve the role of genomics in assessing and […]

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Tags: Bioethics, Cardiovascular Disease, Genetics


June 1, 2020 · Leave a Comment

Seeing cancer, but not through a microscope

By Susan Murphy Susan Murphy (@susanmurphy)

By Marla Broadfoot, Ph.D. / Discovery’s Edge Toward the end of the 19th century, a French doctor named Ernest Besnier coined the term “biopsy,” combining the Greek bios (life) and opsis (a sight). In the decades since, clinicians have performed countless biopsies on suspected cancer patients, all to catch a glimpse of cells on the […]

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Tags: cancer, Cancer Research, Genetics, Research


May 26, 2020 · Leave a Comment

Transplant: Research Makes More Organs Count

By Susan Murphy Susan Murphy (@susanmurphy)

By Sara Nick/ Discovery’s Edge Several years ago, a surgeon checked on his patient and was pleased to find her sipping hot coffee in her hospital bed just one day after a lung transplant. If he was looking for a sign that the operation went well, he found it that morning. Delight turned to devastation […]

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Tags: #bacterial infections, #kidney transplant, Genetic Testing, Genetics, organ transplant


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