Items Tagged ‘Genome Sequencing’

December 23, 2014

Don’t Change Breast Cancer Guidelines on Flawed Research

By Center for Individualized Medicine Center for Individualized Medicine

    Clinical recommendations discouraging the use of CYP2D6 gene testing to guide tamoxifen therapy in breast cancer patients are based on studies with flawed methodology and should be reconsidered, according to the results of a Mayo Clinic study published in the Journal of the National Cancer Institute. For years, controversy has surrounded the CYP2D6 […]

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Tags: biomarker, biomarkers, cancer, center for individualized medicine, CYP2D6, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genome science, Genome Sequencing


Staying One Step Ahead of Cancer

December 18, 2014

Staying One Step Ahead of Cancer

By Center for Individualized Medicine Center for Individualized Medicine

    Four researchers at Mayo Clinic combined their talents to spur a “bedside to bench” movement that takes the issues they face in the clinic back to the laboratory in the hopes of discovering biomarkers to help specific patients facing difficult medical problems. George Vasmatzis, Ph.D., co-director of Mayo Clinic’s Biomarker Discovery Program in […]

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Tags: Andrew Feldman, biomarker, biomarkers, center for individualized medicine, Dennis Wigle, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics


December 16, 2014

Mayo Clinic CEO on Charlie Rose Show

By Center for Individualized Medicine Center for Individualized Medicine

   

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing, Genomic, genomic medicine, genomics, individualized medicine, Individualized Medicine Clinic


Tracing the Lineage of Lung Cancer Tumors

December 9, 2014

Tracing the Lineage of Lung Cancer Tumors

By Center for Individualized Medicine Center for Individualized Medicine

    A diagnostic test based on chromosomal rearrangements can trace the lineage of lung cancer to determine whether two separate lung cancers in the same patient are independent tumors or a tumor that has spread to another region of the lung, a Mayo Clinic study has found. For patients with multiple tumors, that distinction […]

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Tags: biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science


December 5, 2014

Realizing the Opportunities of Genomics in Health Care

By Center for Individualized Medicine Center for Individualized Medicine

    Speaking at the Individualizing Medicine Conference 2014, Geoffrey Ginsburg, M.D. discussed the opportunities for genetics in medicine around the areas of sequencing, data sharing, eMedicine and more. Dr. Geoffrey Ginsburg is the founding director of the Center for Applied Genomics in the Duke University Medical Center and the founding executive director of the […]

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Tags: Biobank, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics


Diversity in Your Gut Influences Your Health

December 3, 2014

Diversity in Your Gut Influences Your Health

By Center for Individualized Medicine Center for Individualized Medicine

    Before reaching for that daily antacid, you might consider what it’s doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among their gut bacteria, putting them at increased […]

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Tags: bacteria, biomarker, biomarkers, center for individualized medicine, DNA Sequencing, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing


Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall

November 13, 2014

Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall

By Center for Individualized Medicine Center for Individualized Medicine

Zhiguo Zhang, Ph.D. and colleagues from the Center for Individualized Medicine, offer a new tool for genomic research, through a new method revealing genome-wide association of proteins with leading and lagging strands of DNA replication forks. This will provide a tool for studying the general replication-related processes and a specific mechanism that makes this possible. […]

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Tags: center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science, Genome Sequencing, Genomic


Individualizing Medicince 2014 Conference: Recap

November 11, 2014

Individualizing Medicince 2014 Conference: Recap

By Center for Individualized Medicine Center for Individualized Medicine

  Quoting “the great poet from Hibbing, Minn.,” genomics pioneer Richard Weinshilboum, M.D., captured the spirit of the third annual Individualizing Medicine Conference 2014: From Promise to Practice when he invoked the legendary Bob Dylan. “‘The times they are a changin’,” Dr. Weinshilboum said. The times are changing indeed. More than 750 physicians, researchers, scientists, medical […]

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Tags: Biobank, Bioethics, biomarker, biomarkers, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic


What is Individualized Medicine?

November 10, 2014

What is Individualized Medicine?

By Center for Individualized Medicine Center for Individualized Medicine

  What exactly does it mean when you hear the phrase “individualized medicine?”   Dr. Alexander Parker of the Center for Individualized Medicine at Mayo Clinic Florida, sat down with the Mayo Clinic Radio Health Minute to explain exactly what individualized medicine means.           _______

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Tags: Alex Parker, Alexander Parker, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome, genome science


Genetic Markers for Alcoholism Recovery Discovered at Mayo Clinic

November 6, 2014

Genetic Markers for Alcoholism Recovery Discovered at Mayo Clinic

By Center for Individualized Medicine Center for Individualized Medicine

  Post originally featured on Mayo Clinic’s News Network, written by Bob Nellis   In an international study, Mayo Clinic researchers and collaborators have identified genetic markers that may help in identifying individuals who could benefit from the alcoholism treatment drug acamprosate. The findings, published in the journal Translational Psychiatry, show that patients carrying these […]

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Tags: Alcoholism, Alcoholism Recovery, biomarker, biomarkers, center for individualized medicine, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics, genome


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