Items Tagged ‘genomics’
September 14, 2021
Mayo researchers link gut microbiome to rheumatoid arthritis prognosis
By Susan Murphy 
A significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in their gut, according to new research from Mayo Clinic’s Center for Individualized Medicine. The study, published in Genome Medicine, found that predicting a patient’s future rheumatoid arthritis prognosis could be possible by zeroing in […]
Tags: #Dr. Jaeyun Sung, Dr. John Davis, genomics, microbiome, Rheumatoid Arthritis
August 31, 2021
By Susan Murphy
Konstantinos Lazaridis, M.D., known for his significant contributions in genomic research and medicine in a quest to predict and better diagnose disease, as well as devise individualized treatments, has been named the Carlson and Nelson Endowed Executive Director for Mayo Clinic’s Center for Individualized Medicine. The center is widely recognized as one of the most […]
Tags: cancer genomics, Dr. Konstantinos Lazaridis, genomics, individualized medicine, multi-omics, rare disease
August 18, 2021
Uterine microbe found to have disease-causing behavior in endometrial cancer
By Susan Murphy
A tiny microbe thriving in the uterine microbiome — a population of bacteria, viruses, yeasts/fungi in and around the uterus— could be a contributing driver of endometrial cancer, according to a new Mayo Clinic study. “We have found that a microbe that is particularly associated with endometrial cancer is capable of pathogenic behavior, and is […]
Tags: Endometrial cancer, genomics, individualized medicine, Omics
July 1, 2021
By Susan Murphy
Rochester, Minn. — Mayo Clinic researchers have discovered that genetic variants in a neuro-associated gene called SPTBN1 are responsible for causing a neurodevelopmental disorder. The study, published in Nature Genetics, is a first step in finding a potential therapeutic strategy for this disorder, and it increases the number of genes known to be associated with […]
June 24, 2021
Mayo researchers develop algorithm to predict rheumatoid arthritis disease activity
By Susan Murphy
Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in a patient. The algorithm analyzes biochemical metabolites ― the product of the body’s metabolism ― in blood. “Having fast, reliable and scalable measures for predicting the clinical course […]
Tags: #algorithm, genomics, Precision Medicine, Rheumatoid Arthritis
March 7, 2021
By Susan Murphy
In honor of International Women’s Day on March 8, Mayo Clinic’s Center for Individualized Medicine is celebrating the inspirational women who are taking on incredible challenges and leading the way to cure, connect and transform health care. International Women’s Day is dedicated to the social, economic, political, cultural and scientific achievements of women. This year’s […]
Tags: #women's health, ALS, cancer, Genetic Testing, genomics, neurodegenerative disorders, rare disease, womens cancer
December 24, 2020
2020 Mayo Clinic Precision Medicine Advances
By Susan Murphy
This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]
Tags: #Artificial Intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research
October 30, 2020
Human Genome Project — ‘A race to the starting line’
By Susan Murphy
This month marks the 30th anniversary of the launch of the Human Genome Project, an international endeavor that mapped the 3 billion DNA letters that make up the blueprint of human life. The ambitious project began in October 1990 and was completed in April 2003. Today, researchers and clinicians with Mayo Clinic Center for Individualized […]
Tags: Genomic Sequencing, genomics, Human Genome Project, Omics
October 5, 2020
Center for Individualized Medicine 9th annual conference: Innovate. Connect. Transform.
By Susan Murphy
By Jennifer O’Hara It has been a remarkable year of discoveries and medical advances at Mayo Clinic’s Center for Individualized Medicine. Some innovations include personalized treatments for cancer and rare diseases, and the development of lifesaving artificial intelligence algorithms. All of the center’s efforts are driven by advanced genetic analysis and aimed at providing patients with […]
Tags: #Artificial Intelligence, genomics, individualized medicine, microbiome
June 23, 2020
Controversial CRISPR case in China raises stakes for how genetic research is conducted
By Jay Furst
Mayo Clinic colleagues take a close look at what went wrong with the process in China and how it challenged the implicit “social contract” between science and society In November 2018, a Chinese biophysicist used a gene-editing technique known by the acronym CRISPR to edit human embryos for reproductive purposes, and he announced the birth […]