Items Tagged ‘genomics’
August 16, 2022
Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer
By Susan Murphy 
By Joe Dangor Researchers from the Mayo Clinic Comprehensive Cancer Center and the Mayo Clinic Center for Individualized Medicine are studying a rare genetic condition called Familial Adenomatous Polyposis (FAP) looking for potential ways to prevent colorectal cancer in the general population at an earlier more treatable stage. The researchers’ findings are published in GUT. “Colorectal cancer is the third most common […]
Tags: center for individualized medicine, colon cancer, Dr. Niloy "Jewel" Samadder, genomics, individualized medicine, medical research
August 8, 2022
Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care
Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]
Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic
July 25, 2022
Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19
By Susan Murphy
Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine
July 20, 2022
2022 Gerstner Awardee to investigate gut microbiome link to chemotherapy-induced nausea
By Susan Murphy
Dr. Singh is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract.
Tags: center for individualized medicine, genomic medicine, genomics
July 20, 2022
2022 Gerstner Awardee to investigate dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy
Dr. Sakemura is working to advance immunotherapy efficacy in multiple myeloma cancer by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.
Tags: center for individualized medicine, Genetics, genomics, individualized medicine, medical research, Multiple Myeloma
July 15, 2022
BA.5 omicron variant fueling latest COVID-19 surge
By Susan Murphy
A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. The extensive research and surveillance operation involves conducting hundreds of sequences of the COVID-19 virus each week.
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, medical research
July 6, 2022
Do environmental exposures contribute to human diseases?
By Susan Murphy
Mayo Clinic researchers put the exposome under the microscope to understand links between lifelong exposures and diseases.
Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, exposome, gene sequencing, Genetics, genomics
June 29, 2022
Mayo study validates threshold to determine when an antidepressant is ineffective
By Susan Murphy
Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.
Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine
June 21, 2022
By Susan Murphy
A collaborative team of scientists led by Mayo Clinic’s Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome. Symptoms of the disorder range from speech and motor impairment to behavioral abnormalities, intellectual disability and distinctive facial features.
Tags: #neurological disorders, center for individualized medicine, Dr. Margot Cousin, gene sequencing, genomics, medical research, personalized medicine
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: Cardiovascular Disease, center for individualized medicine, Center for Regenerative Medicine, genomics, Heart Disease, individualized medicine