Items Tagged ‘genomics’
July 20, 2022
2022 Gerstner Awardee to investigate gut microbiome link to chemotherapy-induced nausea
By Susan Murphy 
Dr. Singh is investigating individualized strategies to help mitigate symptoms of chemotherapy-induced nausea in patients receiving chemotherapy for breast cancer. Her research focuses on the complex link between nausea-related symptoms and the gut microbiome — a population of bacteria, viruses, and fungi that inhabit the gastrointestinal tract.
Tags: center for individualized medicine, genomic medicine, genomics
July 20, 2022
2022 Gerstner Awardee to investigate dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy
Dr. Sakemura is working to advance immunotherapy efficacy in multiple myeloma cancer by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.
Tags: center for individualized medicine, Genetics, genomics, individualized medicine, medical research, Multiple Myeloma
July 15, 2022
BA.5 omicron variant fueling latest COVID-19 surge
By Susan Murphy
A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. The extensive research and surveillance operation involves conducting hundreds of sequences of the COVID-19 virus each week.
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, medical research
July 6, 2022
Do environmental exposures contribute to human diseases?
By Susan Murphy
Mayo Clinic researchers put the exposome under the microscope to understand links between lifelong exposures and diseases.
Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, exposome, gene sequencing, Genetics, genomics
June 29, 2022
Mayo study validates threshold to determine when an antidepressant is ineffective
By Susan Murphy
Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.
Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine
June 21, 2022
By Susan Murphy
A collaborative team of scientists led by Mayo Clinic’s Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome. Symptoms of the disorder range from speech and motor impairment to behavioral abnormalities, intellectual disability and distinctive facial features.
Tags: #neurological disorders, center for individualized medicine, Dr. Margot Cousin, gene sequencing, genomics, medical research, personalized medicine
May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: Cardiovascular Disease, center for individualized medicine, Center for Regenerative Medicine, genomics, Heart Disease, individualized medicine
May 9, 2022
By Susan Murphy
Mark Pearce, 61, was facing a possible limb amputation, even death, when a multidrug-resistant bacterial infection within his prosthetic hip replacement device started raging in his bloodstream. With his fever soaring to more than 105 degrees, Mark was taken by ambulance, that day in spring of 2020, to Mayo Clinic Hospital in Rochester, Minnesota.
Tags: #bacterial infections, bacteria, bacteriophage therapy, center for individualized medicine, Dr. Gina Suh, Dr. Mark Pagnano, genomics, individualized medicine, infectious disease, personalized medicine, phage therapy
May 5, 2022
Mayo research using DNA to catch cancer, other medical conditions earlier
What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]
Tags: center for individualized medicine, DNA Testing, genomics, individualized medicine, mayo clinic, medical research
April 19, 2022
Iftikhar Kullo, M.D. to serve on National Advisory Council on Human Genome Research
Iftikhar Kullo, MD., has been invited to serve on the National Advisory Council on Human Genome Research (NACHGR) of the National Institutes of Health (NIH), by the Hon’ble Xavier Becerra, Secretary of the Department of Health and Human Services (DHHS), for a term beginning immediately and ending September 30, 2024. The Council advises the DHHS, the […]
Tags: center for individualized medicine, DNA Testing, Dr. Iftikhar Kullo, gene sequencing, Genetics, genomics, individualized medicine, medical research