Items Tagged ‘George Vasmatzis’
June 2, 2015
By Jeff Briggs 
Biomarkers are molecular substances in the body that can be used to indicate health or disease. These biomarkers can be found in tissue, blood, urine and other body fluids. Prostate and ovarian cancers are two examples of how the use of biomarkers can lead to individualized diagnosis and treatment. A third example is lung cancer. […]
Tags: biomarker, biomarkers, cancer, center for individualized medicine, Genome Sequencing, George Vasmatzis
December 18, 2014
Staying One Step Ahead of Cancer
By Center for Individualized Medicine
Four researchers at Mayo Clinic combined their talents to spur a “bedside to bench” movement that takes the issues they face in the clinic back to the laboratory in the hopes of discovering biomarkers to help specific patients facing difficult medical problems. George Vasmatzis, Ph.D., co-director of Mayo Clinic’s Biomarker Discovery Program in […]
Tags: Andrew Feldman, biomarker, biomarkers, center for individualized medicine, Dennis Wigle, DNA, DNA Sequencing, dna test, DNA Testing, gene sequencing, genetic, Genetics
August 12, 2014
Bringing Genomics From the Lab to the Patient
By Center for Individualized Medicine
Speaking at the Individualizing Medicine Conference last year, Gianrico Farrugia, M.D., Medical Director of the Center for Individualized Medicine at Mayo Clinic, gave an overview of the work being done in genomics at Mayo Clinic, and the future of health care through the Individualized Medicine Clinic. The Individualized Medicine Clinic (IM Clinic) offers genomic […]
Tags: Biobank, Bioethics, biomarker, biomarkers, breast cancer, cancer, center for individualized medicine, DNA, DNA Sequencing, dna test, DNA Testing, exome
June 17, 2014
By AJ Montpetit
George Vasmatzis, Ph.D., and John Cheville, M.D., co-directors of the Biomarker Program at the Center for Individualized Medicine at Mayo Clinic, introduce us to the world and work of Biomarkers. Biomarkers are molecular substances in the body that can be used to indicate health or disease. These biomarkers can be found in tissue, blood, urine […]
Tags: biomarker, biomarkers, cancer, center for individualized medicine, DNA, dna test, DNA Testing, gene sequencing, Genetics, genome, genome science, Genome Sequencing
November 21, 2013
ASCL1 And RET Expression Defines Clinically Relevant Subgroup Of Lung Adenocarcinoma
By Center for Individualized Medicine
A recent publication, featuring the Director of the Biomarker Discovery Program at the Center for Individualized Medicine at Mayo Clinic, George Vasmatzis, examining the role of ASCL1 in the neuroendocrine differentiation of lung adenocarcinoma. The clinical significance of neuroendocrine differentiation in lung adenocarcinoma, and the most appropriate biomarkers for this assessment, has long been debated. In the […]
Tags: ASCL1, biomarker, Biomarker Discovery, Biomarker Discovery Program, cancer, center for individualized medicine, chromogranin, DNA, George Vasmatzis, immunohistochemical, individualized medicine, Lung Cancer
October 17, 2013
Discovering Smoker’s Lung Cancer Biomarker
By AJ Montpetit
Researchers at Mayo Clinic recently found that a specific pair of proteins may be a successful prognostic biomarker for identifying smoking-related lung cancers. The clinical significance of neuroendocrine (NE) differentiation in lung adenocarcinoma (AD), and the most appropriate biomarkers for this assessment, has long been debated. In the absence of a gold standard, investigators have most […]
Tags: biomarker, biomarkers, cancer, center for individualized medicine, George Vasmatzis, Lung Cancer, Personal Care, Personal Medicine, personalized care, personalized medicine, Smoke, Smoker
September 12, 2013
New Publication from Center for Individualized Medicine
By AJ Montpetit
Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma Abstract Chromosomal translocations leading to expression of abnormal fusion proteins play a major role in the pathogenesis of various hematologic malignancies. The recent development of high-throughput, “deep” sequencing has allowed discovery of novel translocations leading to a rapid increase in understanding these diseases. Translocations […]
Tags: center for individualized medicine, gene sequencing, genome, Genomic Sequencing, genomics, George Vasmatzis, individualized medicine, personalized medicine, RNA
August 1, 2013
By Center for Individualized Medicine
In a recently published article in Hemotology, Center for Individualized Medicine faculty George Vasmatzis, Ph.D., co-authored a study in high resolution mate-pair sequencing. With the use of high resolution mate-pair sequencing (HRMPS) in 15 patients with primary myelofibrosis (PMF): eight with normal karyotype and seven with PMF-characteristic cytogenetic abnormalities, including der(6)t(1;6)(q21–23;p21.3) (n = 4), der(7)t(1;7)(q10;p10) (n = 2), […]
Tags: center for individualized medicine, genetic, genome, George Vasmatzis, individualized medicine, mate-pair, mate-pair sequencing, myelofibrosis, personalized medicine, whole genome sequencing