May 26, 2022
Molecular mapping of the heart to predict disease susceptibility
Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]
Tags: Cardiovascular Disease, center for individualized medicine, Center for Regenerative Medicine, genomics, Heart Disease, individualized medicine
June 8, 2021
Mayo researchers study genetic basis of high cholesterol in adults
In a new study published in NPJ Genomic Medicine, Mayo Clinic researchers found that genetic testing may help identify patients with high cholesterol, or hypercholesterolemia. It also may have implications for the clinical management of patients diagnosed with high cholesterol due to a genetic disorder, or familial hypercholesterolemia. “In our study, we found more than […]
Tags: #Familial hypercholesterolemia, #High cholesterol, Dr. Iftikhar Kullo, Heart Disease, mayo clinic, Mayo Clinic Center for Individualized Medicine
November 28, 2019
For one patient, sharing her family medical history led to lifesaving care
By Sharon Rosen
When Stephanie Van Doren first visited Mayo Clinic’s campus in Florida, she was seeking care for digestive issues. But after hearing Van Doren’s family medical history and completing a clinical evaluation, gastroenterologist Timothy Woodward, M.D. recognized that she may also be at risk for a potentially fatal heart condition, aortic dissection. Genetic testing confirmed that […]
Tags: #aortic dissection, #family medical history, #hereditary diseases, #Stephanie Van Doren, center for individualized medicine, Genetic Testing, genomics, Heart Disease, mayo clinic, Timothy Woodward
June 28, 2019
Can BioBanks Help Close Gaps in Health Outcomes?
By definition, personalized medicine requires diversity. One-size-fits-all doesn’t work for every individual, especially members of groups that are medically underserved. In collaboration with Arizona State University and Mountain Park Health Center (MPHC) in Phoenix, Mayo Clinic’s Center for Individualized Medicine has created a biobank to enhance the diversity of Mayo’s medical research. Sangre Por Salud (Spanish for […]
Tags: #Arizona State University, #diabetes, #disease risk, #Dr. Richard Caselli, #Giovanna Moreno Garzon, #Health Disparities, #high blood pressure, #Mayo Clinic Biobank, #Mountain Park Health Center, #obesity, #Sangre Por Salud, #underserved populations
July 30, 2018
Tool of the trade: researcher applies artificial intelligence to uncover causes, risks for disease
By Sharon Rosen
Some diseases, such as certain breast and colon cancers, are linked to genetic mutations passed down in families. But for many other diseases there are no direct genetic links that explain why the disease develops. That’s why Manolis Kellis, Ph.D. and his team are using artificial intelligence to uncover the hidden cause of disease. Dr. […]
Tags: #CIMCon18, #computational genetics, #Dr. Manolis Kellis, #Dr. Tamas Ordog, #Individualizing Medicine 2018, #Massachusetts Institute of Technology, #mathematical models, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, #MIT Computational Biology Group, #obesity, Alzheimer’s disease, center for individualized medicine
February 13, 2018
Genetic cardiovascular disease: Is your family at risk?
With cardiovascular disease a leading cause of death, it’s fair to say that many people have been touched by this disorder. Maybe a family member died suddenly of a heart attack, or a friend suffered a disabling stroke. February is American Heart Month, a great time to talk about the precision approach Mayo Clinic Center […]
Tags: #Familial hypercholesterolemia, #FH, #Genetic risk, #High cholesterol, #Mayo Clinic Department of Cardioscular Diseases, #Mayo Clinic Department of Clinical Genomics, #Stroke, Cardiovascular Disease, Dr. Iftikhar Kullo, Genetic Testing, heart attack, Heart Disease
February 6, 2018
A new approach to heart disease: individualized therapies for men and women
By Sharon Rosen
February is American Heart Month. According to DeLisa Fairweather, Ph.D., it’s a critical time in the fight against heart disease, the leading cause of death for both men and women in the U.S. She and her research team at Mayo Clinic’s Florida campus are taking a new approach – they’re exploring how heart disease develops […]
Tags: #CIMCon18, #Dr. DeLisa Fairweather, #inflammatory diseases, #Lupus, #myocarditis, #sex differences, #Translational Cardiovascular Disease Research Laboratory, #women's health, cardiomyopathy, center for individualized medicine, DNA Testing, Genetic Testing
June 30, 2017
Pharmacogenomics – striving for safer, more effective drugs for you
By Sharon Rosen
At Mayo Clinic, pharmacogenomics – how your genes impact the way you process medications – is helping doctors to take the guess work out of selecting safer, more effective treatment for patients. Mayo researchers have been leaders in developing DNA tests and identifying drug-gene interactions that affect a patient’s response to many medications, such as […]
Tags: #CIMCon17, #drug safety, #drug-gene reactions, #Karen Daggett, center for individualized medicine, Dr. Eric Matey, Dr. Liewei Wang, Dr. Richard Weinshilboum, Heart Disease, mayo clinic, Mayo Clinic Pharmacogenomics Program, medical research
April 14, 2017
Precision care for heart disease – a practical approach
By Sharon Rosen
Heart disease can sometimes be a silent killer. Many of us know seemingly healthy people who’ve suddenly or unexpectedly had a heart attack. It can be shocking when people who are at a a healthy weight and exercise regularly die from heart disease that they never knew they had. Many forms of heart disease can […]
Tags: #atrial fibrillation, #cardiology, #Dr. Iftkhar Kullo, #Dr. John Giudicessi, #Dr. Michael Ackerman, #drug-gene reactions, #familial cardiovascular diseases, #sudden cardiac death, #targeted therapies, center for individualized medicine, coronary heart disease, Genetic Testing
February 3, 2014
National Wear Red Day This Friday
By Center for Individualized Medicine
At the Center for Individualized Medicine, we are working to combat the No. 1 killer of men and women in the United States at the genomics level: Heart disease. We wanted to start this week off by sharing this informative image below on the facts on heart disease that affect women, and show our support […]
Tags: DNA Sequencing, genome, Genome Sequencing, genomics, Heart Disease, Heart Health, individualized medicine, personalized care, personalized medicine, Wear Red