Items Tagged ‘individualized medicine’

June 13, 2022

Native American’s genetic test results at Mayo Clinic reveal surprise lineage to ancient tribe   

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic working to advance health equity among Native Americans, Alaska Natives Schyler Martin, a member of the Munsee Band of Mohicans in Minnesota, was surprised and excited when his recent Mayo Clinic genetic test results revealed he has distinctive DNA lineage to an ancient group of Native Americans known as the Beringians. According to […]

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Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, Genetic Testing, Genetics, genomic medicine, individualized medicine, medical research, tapestry


May 26, 2022

Molecular mapping of the heart to predict disease susceptibility

By Susan Buckles Susan Buckles (@susanbuckles)

Vulnerability to heart disease can be projected before symptoms occur, Mayo Clinic discovered in preclinical research. This proof-of-concept study revealed that heart muscle changes indicate who is vulnerable to disease later in life. These changes can be detected from blood samples through comprehensive protein and metabolite profiling. This exploratory mapping, conducted in the Marriott Family […]

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Tags: Cardiovascular Disease, center for individualized medicine, Center for Regenerative Medicine, genomics, Heart Disease, individualized medicine


May 19, 2022

Study indicates gut microbiome, host gene affect gastrointestinal disorders

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research, personalized medicine


May 9, 2022

Mayo patient with life-threatening multidrug-resistant infection treated with experimental phage therapy combined with surgery  

By Susan Murphy Susan Murphy (@susanmurphy)

Mark Pearce, 61, was facing a possible limb amputation, even death, when a multidrug-resistant bacterial infection within his prosthetic hip replacement device started raging in his bloodstream. With his fever soaring to more than 105 degrees, Mark was taken by ambulance, that day in spring of 2020, to Mayo Clinic Hospital in Rochester, Minnesota. 

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Tags: #bacterial infections, bacteria, bacteriophage therapy, center for individualized medicine, Dr. Gina Suh, Dr. Mark Pagnano, genomics, individualized medicine, infectious disease, personalized medicine, phage therapy


May 5, 2022

Mayo research using DNA to catch cancer, other medical conditions earlier

By Adam Harringa Adam Harringa (@harringaadam)

What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]

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Tags: center for individualized medicine, DNA Testing, genomics, individualized medicine, mayo clinic, medical research


April 19, 2022

Iftikhar Kullo, M.D. to serve on National Advisory Council on Human Genome Research

By Colette Gallagher Colette Gallagher (@colettegallagher)

Iftikhar Kullo, MD., has been invited to serve on the National Advisory Council on Human Genome Research (NACHGR) of the National Institutes of Health (NIH), by the Hon’ble Xavier Becerra, Secretary of the Department of Health and Human Services (DHHS), for a term beginning immediately and ending September 30, 2024. The Council advises the DHHS, the […]

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Tags: center for individualized medicine, DNA Testing, Dr. Iftikhar Kullo, gene sequencing, Genetics, genomics, individualized medicine, medical research


April 13, 2022

Mayo Clinic researchers load CAR-T cells with oncolytic virus to treat solid cancer tumors

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers at Mayo Clinic’s Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors. 

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Tags: #CAR T-cell therapy, center for individualized medicine, Dr. Richard Vile, genomics, individualized medicine, medical research, oncolytic virus, personalized medicine


March 22, 2022

Study involving investigators from Mayo Clinic, Baylor College of Medicine applies drug-gene testing to improve patient care and reports outcomes

By Colette Gallagher Colette Gallagher (@colettegallagher)

The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.

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Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics


March 16, 2022

Mayo Clinic researchers use AI to predict antidepressant outcomes in youth

By Colette Gallagher Colette Gallagher (@colettegallagher)

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry.

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic, medical research, personalized medicine


February 24, 2022

Curiosity paves path to precision medicine research

By Susan Murphy Susan Murphy (@susanmurphy)

By  Mayo Clinic Alumni Magazine When John Giudicessi, M.D., Ph.D., was growing up in Des Moines, Iowa, he fueled his incessant curiosity by taking apart unused items in the family’s basement. He caught frogs and turtles in a backyard creek. He loved figuring out how things worked. His parents encouraged him to ask questions. Dr. Giudicessi […]

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Tags: center for individualized medicine, DNA Testing, Genetics, genomic medicine, genomics, individualized medicine, medical research


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