Items Tagged ‘individualized medicine’

September 22, 2022

Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]

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Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research


September 7, 2022

What is the benefit of visiting a genetic counselor?

By Susan Murphy Susan Murphy (@susanmurphy)

By Cynthia Weiss DEAR MAYO CLINIC: My grandmother and mother, as well as an aunt and a cousin, have had breast cancer. Another cousin was diagnosed with colon cancer recently. It has been suggested that I undergo genetic counseling to determine my cancer risk. As a young man, is genetic testing necessary for me? What benefit […]

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Tags: center for individualized medicine, DNA Testing, gene sequencing, Genetics, genomic medicine, individualized medicine


August 16, 2022

Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer

By Susan Murphy Susan Murphy (@susanmurphy)

By Joe Dangor Researchers from the Mayo Clinic Comprehensive Cancer Center and the Mayo Clinic Center for Individualized Medicine are studying a rare genetic condition called Familial Adenomatous Polyposis (FAP) looking for potential ways to prevent colorectal cancer in the general population at an earlier more treatable stage. The researchers’ findings are published in GUT. “Colorectal cancer is the third most common […]

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Tags: center for individualized medicine, colon cancer, Dr. Niloy "Jewel" Samadder, genomics, individualized medicine, medical research


August 8, 2022

Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care

By Colette Gallagher Colette Gallagher (@colettegallagher)

Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]

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Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic


August 1, 2022

New AI algorithm opens avenues for knowledge discoveries

By Colette Gallagher Colette Gallagher (@colettegallagher)

In a proof-of-concept study published in Frontiers in Immunology, Hu Li, Ph.D., a Mayo Clinic Center for Individualized Medicine systems biologist, developed a new artificial intelligence (AI) algorithm which uses novel weight engineering methods to extract meaningful biological knowledge learned by AI models. He and his team applied the tool to breast cancer omic data […]

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Tags: Cancer Research, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine


July 25, 2022

Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19

By Susan Murphy Susan Murphy (@susanmurphy)

Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]

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Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine


July 22, 2022

The new precision stewards? A research agenda for ethical, legal and social aspects of antimicrobial resistance

By Colette Gallagher Colette Gallagher (@colettegallagher)

In this blog synopsis,  Karen Meagher, Ph.D., Assistant Professor and Associate Director of Public Engagement for Mayo Clinic Biomedical Ethics Research Program writes about the ethical aspects of antimicrobial resistance. If only traditional susceptibility testing took less time. If only there was a way to get the most personalized microbial profile into the hands of […]

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Tags: center for individualized medicine, individualized medicine, mayo clinic


July 20, 2022

2022 Gerstner Awardee to investigate dual CAR-T cell therapy for multiple myeloma cancer

By Susan Murphy Susan Murphy (@susanmurphy)

Dr. Sakemura is working to advance immunotherapy efficacy in multiple myeloma cancer by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment. 

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Tags: center for individualized medicine, Genetics, genomics, individualized medicine, medical research, Multiple Myeloma


July 15, 2022

BA.5 omicron variant fueling latest COVID-19 surge

By Susan Murphy Susan Murphy (@susanmurphy)

A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. The extensive research and surveillance operation involves conducting hundreds of sequences of the COVID-19 virus each week.

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Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, medical research


June 29, 2022

Mayo study validates threshold to determine when an antidepressant is ineffective

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.

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Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine


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