Items Tagged ‘individualized medicine’

September 15, 2020

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: bacteria, Gut Microbiome, individualized medicine, Microbiome Program


September 10, 2020

Mayo Clinic researcher finds potential target to control rare genetic disease that strikes in teen years

By Susan Murphy Susan Murphy

Patients with a rare genetic disease called familial adenomatous polyposis, (FAP), often face debilitating challenges. Typically striking in the early teenage years, FAP is characterized by hundreds to thousands of tiny polyps forming in the colon and rectum and leading to a nearly 100% percent likelihood that they will get colon cancer without a life-altering […]

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Tags: Genetic Testing, Genetics, hereditary cancer, hereditary colon cancer, individualized medicine


September 10, 2020

Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain

By Susan Murphy Susan Murphy

Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020 issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve […]

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Tags: individualized medicine, irritable bowel syndrome, microbiome, multi-omics


August 25, 2020

Largest pharmacogenetics clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy

By Susan Murphy Susan Murphy

By Terri Malloy Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in […]

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Tags: #cardiology, Cardiovascular Disease, individualized medicine, pharmacogenomics


December 23, 2019

Meet Eric Matey, Pharm.D., R.Ph.: moving drug-gene testing into clinical care

By Sharon Rosen Sharon Rosen

If you’ve picked up a prescription from your local pharmacy, you may have spoken with a pharmacist about how and when to take a medication or its potential side effects. At Mayo Clinic, pharmacists perform these same tasks, but their role extends much further by helping move genomics discoveries into clinical care.   “Our pharmacy team […]

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Tags: #drug-gene interactions, #RIGHT 10K study, center for individualized medicine, Center for Individualized Medicine Pharmacogenomics Program, Eric Matey, Genetic Testing, genomics, individualized medicine, mayo clinic, pharmacy


December 11, 2019

In a first, researchers sequence single bacterial cells, paving path for rapid sepsis test

By Susan Murphy Susan Murphy

For the first time, Mayo Clinic researchers are sequencing the genomic contents of single bacterial cells. The technique may pave the way for a potential lifesaving test for sepsis, a serious and sometimes deadly condition caused by the body’s response to an infection. Rather than waiting for days to identify the source of a patient’s […]

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Tags: #sepsis, bacteria, bacterial cells, Genome Sequencing, individualized medicine


September 25, 2019

The BEAUTY of it: award recognizes personalized medicine approach for breast cancer

By Barbara J. Toman Barbara J. Toman

A Mayo Clinic research team supported by the Center for Individualized Medicine is making significant breakthroughs — and gaining recognition for them. The Breast Cancer Genome-Guided Therapy (BEAUTY) project has received the 2019 Mayo Clinic Team Science Award, given for interdisciplinary work that substantially advances Mayo’s research. The award cites BEAUTY’s discoveries about breast tumor […]

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Tags: #targeted therapies, BEAUTY trial, breast cancer, center for individualized medicine, chemotherapy, chemotherapy-resistant breast cancer, Dr. Judy Boughey, Dr. Liewei Wang, Dr. Matthew Goetz, Genetics, genomics, individualized medicine


September 19, 2019

One Discovery Square provides a hub for innovation, state-of-the-art labs, top researchers

By Susan Murphy Susan Murphy

Researchers, physicians and staff with the Advanced Diagnostics Laboratory, a joint collaboration between the Mayo Clinic Department of Laboratory Medicine and Pathology and the Center for Individualized Medicine, will take part in a community celebration of One Discovery Square on Sept. 19 from 4-6 p.m. The grand opening event, held in conjunction with the Destination […]

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Tags: #Artificial Intelligence, center for individualized medicine, Destination Medical Center, Dr. Keith Stewart, Genetics, genomics, individualized medicine, mayo clinic, Mayo Clinic Advanced Diagnostic Laboratory, Mayo Clinic Center for Individualized Medicine, Mayo Clinic Department of Laboratory Medicine and Pathology, medical research


August 27, 2019

Meet Margot Cousin, Ph.D.: Genetic detective, researcher, member of the A-team

By Sharon Rosen Sharon Rosen

When a young boy arrived at Mayo Clinic after repeatedly experiencing infections that caused a fever and a rapid loss of liver function, clinicians turned to genetic testing to find the cause of the illness. Margot Cousin, Ph.D., a translational genomics researcher in the Mayo Clinic Center for Individualized Medicine Translational Omics Program was among […]

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Tags: #liver cancer, acute liver failure, American Association for the Study oF Liver Disease, center for individualized medicine, Dr. Eric Klee, Dr. Konstantinos Lazaridis, Dr. Margot Cousin, Genetic Testing, genomics, Genomics Odyssey Board, individualized medicine, Liver disease


July 25, 2019

Antoni Ribas, M.D., Ph.D. – leading melanoma researcher to speak at #CIMCON19

By Sharon Rosen Sharon Rosen

Article by Sara Damore Melanoma is an aggressive skin cancer caused by extensive sun exposure and the fifth most common cancer in the U.S. If detected and treated early, the survival rates for melanoma are high (98%). However, once the cancer spreads to other areas of the body, survival rates for malignant melanoma drop dramatically […]

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Tags: #CIMCon19, #skin cancer, BRAF gene, center for individualized medicine, Dr. Antoni Ribas, geenetics, genomics, Herpes virus, immunotherapy, individualized medicine, mayo clinic, Melanoma


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