Items Tagged ‘individualized medicine’

March 18, 2021

New Framework Leads to Surprise in Early Human Development

By Sara Tiner Sara Tiner (@saratiner)

Mayo Clinic and Yale University scientists have developed a minimally invasive process for studying early cell development in a living person. The team reconstructed the cell history of two adult volunteers from just after cell fertilization. They found that in the first cell divide — 29 years earlier for one volunteer and 66 years earlier […]

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Tags: cells, genome, individualized medicine, Research


January 19, 2021

Mayo researchers explore genetics behind COVID-19 outcomes

By Susan Murphy Susan Murphy (@susanmurphy)

Some patients with COVID-19 experience severe complications, such as organ damage, shortness of breath, neurological impairment and chronic fatigue. A team of researchers within Mayo Clinic Center for Individualized Medicine is contributing to the global effort of using advanced genetic sequencing to find out which genes influence disease outcomes. “Our findings will be crucial in […]

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Tags: covid-19, Genetic Testing, Genetics, Genomic Research, individualized medicine, Research


December 24, 2020

2020 Mayo Clinic Precision Medicine Advances

By Susan Murphy Susan Murphy (@susanmurphy)

This year, Mayo Clinic’s Center for Individualized Medicine was at the forefront of COVID-19 research, working to unravel the complexities of the virus in order to discover life-saving treatments and prevention — from testing to building a pandemic response biobank to identifying COVID-19 strains within individual patients. But even in the midst of the pandemic, […]

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Tags: artificial intelligence, Cancer Research, Genetics, genomics, individualized medicine, multi-omics, Research


October 20, 2020 · Leave a Comment

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

By Susan Murphy Susan Murphy (@susanmurphy)

By Sara Tiner Cells in the body usually do what they’re told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body’s order to expire: senescent cells. Sometimes called “zombie cells” for their undead lingering, senescent cells have triggered the body’s kill […]

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Tags: biomarkers, cells, individualized medicine, Research


October 15, 2020 · Leave a Comment

Research into Experimental COVID-19 Therapeutics Explained

By Susan Murphy Susan Murphy (@susanmurphy)

By Sara Tiner COVID-19 can affect people in a number of ways. Some can be infected and have no symptoms ― what’s known as being asymptomatic. Others have symptoms, but do not have a serious illness. And some can require hospitalization for intensive complications. For those with symptoms or those who are progressing to hospitalization, […]

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Tags: covid-19, individualized medicine


October 5, 2020 · Leave a Comment

Center for Individualized Medicine 9th annual conference: Innovate. Connect. Transform.

By Susan Murphy Susan Murphy (@susanmurphy)

By Jennifer O’Hara It has been a remarkable year of discoveries and medical advances at Mayo Clinic’s Center for Individualized Medicine. Some innovations include personalized treatments for cancer and rare diseases, and the development of lifesaving artificial intelligence algorithms. All of the center’s efforts are driven by advanced genetic analysis and aimed at providing patients with […]

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Tags: artificial intelligence, genomics, individualized medicine, microbiome


September 15, 2020 · Leave a Comment

Mayo scientists develop mathematical index to distinguish healthy microbiome from diseased

By Susan Murphy Susan Murphy (@susanmurphy)

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome — the trillions of microbes living inside the digestive system that regulate various bodily functions. To utilize the huge population of tiny organisms as a […]

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Tags: bacteria, Gut Microbiome, individualized medicine, Microbiome Program


September 10, 2020

Mayo Clinic researcher finds potential target to control rare genetic disease that strikes in teen years

By Susan Murphy Susan Murphy (@susanmurphy)

Patients with a rare genetic disease called familial adenomatous polyposis, (FAP), often face debilitating challenges. Typically striking in the early teenage years, FAP is characterized by hundreds to thousands of tiny polyps forming in the colon and rectum and leading to a nearly 100% percent likelihood that they will get colon cancer without a life-altering […]

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Tags: Genetic Testing, Genetics, hereditary cancer, hereditary colon cancer, individualized medicine


September 10, 2020

Mayo researcher finds potential microbial pathway to treat IBS symptoms, lessen abdominal pain

By Susan Murphy Susan Murphy (@susanmurphy)

Mayo Clinic researchers have found new evidence linking the millions of bacteria residing in our digestive systems, known as the microbiome, to a network of factors that drive irritable bowel syndrome (IBS). The findings, published in the Sept. 10, 2020 issue of Cell, raise the possibility of targeting the newly discovered microbial pathways to improve […]

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Tags: individualized medicine, irritable bowel syndrome, microbiome, multi-omics


August 25, 2020 · Leave a Comment

Largest pharmacogenetics clinical trial in cardiology shows potential benefit in individualized approach to anti-platelet therapy

By Susan Murphy Susan Murphy (@susanmurphy)

By Terri Malloy Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement― nonsurgical procedures to improve blood flow to the heart ― are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in […]

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Tags: #cardiology, Cardiovascular Disease, individualized medicine, pharmacogenomics


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