Items Tagged ‘mate-pair’

August 1, 2013

Identification of Submicroscopic Genetic Changes and Precise Breakpoint Mapping in Myelofibrosis Using High Resolution Mate-Pair Sequencing

By Center for Individualized Medicine

  In a recently published article in Hemotology, Center for Individualized Medicine faculty George Vasmatzis, Ph.D., co-authored a study in high resolution mate-pair sequencing. With the use of high resolution mate-pair sequencing (HRMPS) in 15 patients with primary myelofibrosis (PMF): eight with normal karyotype and seven with PMF-characteristic cytogenetic abnormalities, including der(6)t(1;6)(q21–23;p21.3) (n = 4), der(7)t(1;7)(q10;p10) (n = 2), […]

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Tags: center for individualized medicine, genetic, genome, George Vasmatzis, individualized medicine, mate-pair, mate-pair sequencing, myelofibrosis, personalized medicine, whole genome sequencing