Items Tagged ‘mayo clinic’
September 22, 2022
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research
August 8, 2022
Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care
Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]
Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic
August 1, 2022
New AI algorithm opens avenues for knowledge discoveries
In a proof-of-concept study published in Frontiers in Immunology, Hu Li, Ph.D., a Mayo Clinic Center for Individualized Medicine systems biologist, developed a new artificial intelligence (AI) algorithm which uses novel weight engineering methods to extract meaningful biological knowledge learned by AI models. He and his team applied the tool to breast cancer omic data […]
Tags: Cancer Research, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine
July 25, 2022
Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19
By Susan Murphy 
Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine
July 22, 2022
In this blog synopsis, Karen Meagher, Ph.D., Assistant Professor and Associate Director of Public Engagement for Mayo Clinic Biomedical Ethics Research Program writes about the ethical aspects of antimicrobial resistance. If only traditional susceptibility testing took less time. If only there was a way to get the most personalized microbial profile into the hands of […]
Tags: center for individualized medicine, individualized medicine, mayo clinic
June 8, 2022
The American Association for Cancer Research today released its Cancer Disparities Progress Report 2022. The publication aims to raise awareness of the enormous toll that cancer exacts on racial and ethnic minorities and other diverse and medically underserved populations in the United States while highlighting areas of recent progress in reducing cancer health disparities. The […]
Tags: Cancer Research, cancer screening, center for individualized medicine, health disparities, mayo clinic
May 19, 2022
Study indicates gut microbiome, host gene affect gastrointestinal disorders
In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research, personalized medicine
May 5, 2022
Mayo research using DNA to catch cancer, other medical conditions earlier
What would happen if a certain percentage of serious medical conditions, including cancer diagnoses, were found significantly earlier by studying the entire genome of patients’ DNA? How would their quality of life improve, and how many fewer cancer deaths would there be each year? That’s what a group of Mayo Clinic scientists and clinicians aim […]
Tags: center for individualized medicine, DNA Testing, genomics, individualized medicine, mayo clinic, medical research
March 22, 2022
The results from the “Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment” (RIGHT 10K) study strongly suggest that preemptive testing could benefit nearly every patient at some point, particularly when the testing extends beyond DNA variants already known to influence drug metabolism.
Tags: Baylor College of Medicine, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine, pharmacogenomics
March 17, 2022
Mayo Clinic study reports genomic data disparities among racial groups
Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas. “We found lower quality genomic sequencing data in self-reported Black patients and patients of African ancestry,” says Yan Asmann., Ph.D., a Mayo Clinic bioinformatician and senior […]
Tags: Cancer Research, center for individualized medicine, DNA Testing, mayo clinic