Items Tagged ‘mayo clinic’
February 4, 2019
Meet Chuanhe Yu, Ph.D.: searching for the genetic switches linked to disease
By Sharon Rosen 
Chuanhe Yu, Ph.D. has always had an interest in genetics – the thousands of genes that make each of us unique. His research focuses on the growing field of epigenetics, which aims to better understand how environmental and lifestyle factors cause chain reactions, flipping the switch on genes and the instructions they provide to guide […]
Tags: #cancer biology, #cell biology, #DNA replication, #Dr. Chuanhe Yu, #epigenetics, #epigenome, #eSPAN model, #Mayo Clinic Center for Individualized Medicine Epigenomics Program, cancer, center for individualized medicine, Epigenomics, mayo clinic
January 14, 2019
Using brain organoids to uncover causes of neuropsychiatric disorders
Mayo Clinic and Yale University collaborated in a study published in Science to create a new model for studying neuropsychiatric disorders in early human brain development. This unique collaboration brought together Mayo Clinic’s team-based, patient-centered research with Yale researchers to discover and analyze the genetic mechanisms that may cause these disorders. The Mayo Clinic team, […]
Tags: Alexej Abyzov, autism, brain organoids, mayo clinic, Mayo Clinic Center for Individualized Medicine, neuropsychiatric disorders, Ph.D., Research, Yale University
December 3, 2018
Meet Sanjay Bagaria, M.D.: new CIM associate director in Florida
By Sharon Rosen
Hindsight is 20/20.That saying rings true for surgical oncologist Sanjay Bagaria, M.D. As a premedical student at University of Michigan, he chose to major in Japanese studies, mastering thousands of characters and a new grammar structure to read the Japanese literature he loved. Looking back, that experience gave him the tools to view not only […]
Tags: #Associate director Center for Individualized Medicine, #basal-like breast cancer, #Dr. Sanjay Bagaria, #hyperthermic intraperitoneal chemotherapy (HIPEC) surgery, #Mayo Clinic Campus in Florida, #surgical oncologist, biomarkers, center for individualized medicine, mayo clinic, medical research
November 5, 2018
Pharmacogenomics: finding the right drug, dose for cancer therapy
By Sharon Rosen
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn’t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening […]
Tags: #5-fluorouracil, #5-FU chemotherapy, #chemotherapy side effects, #DPYD gene, #drug-gene interactions, #gene verifier model, breast cancer, chemotherapy, colorectal cancer, mayo clinic, Mayo Clinic Cancer Center, Mayo Clinic Center for Individualized Medicine
October 15, 2018
Personalized screening: finding and treating breast cancer sooner
By Sharon Rosen
October is Breast Cancer Awareness Month, a time to reflect on new, individualized approaches to detecting and treating a cancer that affects 1 in 8 American women. Deborah Rhodes, M.D. and her Mayo Clinic colleagues are working to identify the best targeted screening tools and guidelines for women with a higher risk of developing breast […]
Tags: #breast cancer screening, #dense breast tissue, #Dr. Deborah Rhodes, #Dr. Michael O'Connor, #Dr. Myra Wick, #molecular breast imaging, 3-D mammograms, breast cancer, breast density, center for individualized medicine, Dr. Carrie Hruska, mayo clinic
October 4, 2018
Meet Lisa Schimmenti: Searching for drug therapies to treat hearing loss
By Sharon Rosen
Lisa Schimmenti, M.D. has always been fascinated with Helen Keller and all she accomplished, in spite of being blind and deaf from a very young age. As the newly appointed chair of Mayo Clinic’s Department of Clinical Genomics and a medical geneticist, Dr. Schimmenti cares for patients with similar conditions. In her clinical practice, she sees […]
Tags: #Dr. Lisa Schimmenti, #drug discovery, #hearing aids, #hearing loss, #Mayo Clinic Department of Clinical Genomics, #Mayo Clinic Department of Otorhinolaryngology, #Usher Syndrome, #zebrafish, center for individualized medicine, mayo clinic, medical research
September 24, 2018
CIM CON — What is the impact on health care of genome editing?
Although Mayo Clinic does not use genome editing as part of any treatment in the medical practice, genome editing has promise for treating and even curing previously intractable disorders, such as Duchenne muscular dystrophy. Genome editing, via methods like CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) can be used to facilitate the […]
Tags: #CIMCon18, #CRISPR-Cas9, #Dr. Megan Allyse, #Dr. Shondra Pruett-Miller, #Dr. Stephen Tsang, #duchenne muscular dystrophy, #gene therapy, center for individualized medicine, gene editing, genomics, mayo clinic
September 17, 2018
CIMCON18 — how genomics discovery is transforming individualized care and the path forward
By Sharon Rosen
Mining information deeper than genomics, understanding factors linked to disease, analyzing big data, and addressing the challenges of bringing all this information together to advance patient care – these were some of the themes featured at the Individualizing Medicine Conference: Advancing Care through Genomics held in Rochester, Minnesota, Sept. 12-13, and sponsored by the Mayo […]
Tags: #All of Us Research Program biobank, #CAR T-cell therapy, #CIMCon18, #Dr. Eric Green, #Dr. Gabriel Krestin, #Dr. Manolis Kellis, #Dr. Michael Berger, #Dr. Nancy Cox, #Dr. Yi Lin, #Genomic data, All of Us Research Program, center for individualized medicine
September 4, 2018
Preemptive genetic testing: could it help you take charge of your health?
By Sharon Rosen
A blood pressure check, an immunization and a cholesterol test – these are all parts of your routine medical care. Someday, a genetic test to identify your risk for developing disease may also be added to the list. In fact, researchers believe that day is fast approaching thanks to the rapid advances in genomic medicine. […]
Tags: #CIMCon18, #DNA sequencing tests, #Mayo Clinic Biobank, #pre-emptive genetic testing, center for individualized medicine, Dr. Konstantinos Lazaridis, Genetic Testing, mayo clinic, medical research, whole genome sequencing
August 20, 2018
Preparing the next generation – interns engaged in precision medicine research
By Sharon Rosen
When Zachary Stephens started his summer internship at Mayo Clinic in 2013, he was thrust into a world where solving big data challenges can lead to more individualized care for patients. As a graduate student in electrical and computer engineering at the University of Illinois at Urbana-Champaign, he was used to developing computer models to analyze […]
Tags: #CIMCon18, #Dr. Jean Pierre Kocher, #information technology, #IT, #Mayo Clinic & Illinois Alliance for Technology-based Healthcare, #Mayo Clinic Graduate School of Biomedical Sciences, #medical education, #summer undergraduate research fellowship, #University of Illinois at Urbana Champaign (Illinois), #Zachary Stephens, Bioinformatics, Caer Rohrer Vitek