Items Tagged ‘mayo clinic’
January 24, 2023
Could antidepressants cause treatment-emergent mania?
In a study published in Molecular Psychiatry, Mark Frye, M.D., a Mayo Clinic researcher and collaborators, investigated the risk of treatment-emergent mania in bipolar disorder when treated with antidepressants. “We found that antidepressants that increase mitochondrial energetics (cells that extract energy from nutrients for sustaining life) may elevate the risk of treatment-emergent mania,” says Dr. […]
Tags: center for individualized medicine, mayo clinic, personalized medicine
January 10, 2023
Mayo Clinic Laboratories, a leading reference laboratory, and Helix, the nation’s leading population genomics and viral surveillance company, today announced a new strategic collaboration that will provide biopharma customers access to a comprehensive joint laboratory offering for research and development initiatives across the drug development lifecycle. The offering will include a full spectrum of testing […]
Tags: center for individualized medicine, genomic medicine, genomics, individualized medicine, mayo clinic
December 16, 2022
NIH’s All of Us Research Program returns health-related DNA results to participants
The National Institutes of Health’s (NIH) All of Us Research Program has begun returning personalized health-related DNA results to more than 155,000 participants. The reports detail whether participants have an increased risk for specific health conditions and how their bodies might process certain medications. The All of Us Research Program collects participants’ blood, urine, and saliva samples. These biosamples […]
Tags: All of Us Research Program, center for individualized medicine, Genetics, mayo clinic, medical research, National Institutes of Health
December 13, 2022
Mayo researchers streamline genetic testing in heart failure clinic, improve clinical care
In a new study published in Genetics in Medicine, Mayo Clinic researchers streamlined genetic testing and counseling for patients with dilated cardiomyopathy, a type of heart muscle disease that causes the heart chambers (ventricles) to thin and stretch, growing larger. “We showed that this practice intervention increased the uptake and yield of genetic testing and […]
Tags: center for individualized medicine, Genetic Testing, mayo clinic, medical research
October 18, 2022
In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS). LQTS is a genetic heart disease that can potentially cause fast, chaotic heartbeats. These rapid heartbeats might trigger people to […]
Tags: center for individualized medicine, gene therapy, genomic medicine, individualized medicine, mayo clinic, personalized medicine
September 22, 2022
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research
August 8, 2022
Mayo Clinic researchers integrate genomics into kidney disease diagnosis, care
Genomic testing results evaluated by a team of Mayo Clinic researchers, coupled with the latest research techniques, provided a definitive diagnosis for 30.7% of families with unexplained chronic kidney disease or stones, as reported in a 2021 study published in Kidney Medicine, a Journal of the National Kidney Foundation. The study obtained the highest diagnostic […]
Tags: center for individualized medicine, genomics, individualized medicine, mayo clinic
August 1, 2022
New AI algorithm opens avenues for knowledge discoveries
In a proof-of-concept study published in Frontiers in Immunology, Hu Li, Ph.D., a Mayo Clinic Center for Individualized Medicine systems biologist, developed a new artificial intelligence (AI) algorithm which uses novel weight engineering methods to extract meaningful biological knowledge learned by AI models. He and his team applied the tool to breast cancer omic data […]
Tags: Cancer Research, center for individualized medicine, individualized medicine, mayo clinic, personalized medicine
July 25, 2022
Mayo Clinic researchers pinpoint genetic variations that might sway course of COVID-19
By Susan Murphy 
Researchers at Mayo Clinic’s Center for Individualized Medicine have discovered key human genomic signatures that could help explain why COVID-19 is severe in some people and mild in others. After analyzing volumes of diverse worldwide DNA sequence data, the scientists identified mutations in two human proteins that might sway the course of SARS-CoV-2 — the […]
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, mayo clinic, personalized medicine
July 22, 2022
In this blog synopsis, Karen Meagher, Ph.D., Assistant Professor and Associate Director of Public Engagement for Mayo Clinic Biomedical Ethics Research Program writes about the ethical aspects of antimicrobial resistance. If only traditional susceptibility testing took less time. If only there was a way to get the most personalized microbial profile into the hands of […]
Tags: center for individualized medicine, individualized medicine, mayo clinic