Items Tagged ‘medical research’
September 22, 2022
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research
September 15, 2022
Designing Personalized Vaccines to Combat Cancer
By Susan Murphy 
Mayo Clinic researchers are working to develop personalized therapeutic cancer vaccines that can potentially target each person’s distinctive tumor characteristics. The new approach, built on advances in genomic research and data analytics, holds transformative potential to boost the power of the immune system to identify and attack cancer cells.
Tags: Cancer Research, cancer vaccine, center for individualized medicine, Genetics, medical research, neoantigen, personalized medicine
August 31, 2022
Critical Questions About AI: A Researcher Takes Pulse of Clinicians, Patients
By Susan Murphy
Richard Sharp, Ph.D., director of Mayo Clinic’s Biomedical Ethics Research Program, is heading a team studying what people think about medical innovations like genetic testing, neuromodulation and now AI.
Tags: center for individualized medicine, genomic medicine, medical research
August 16, 2022
Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer
By Susan Murphy
By Joe Dangor Researchers from the Mayo Clinic Comprehensive Cancer Center and the Mayo Clinic Center for Individualized Medicine are studying a rare genetic condition called Familial Adenomatous Polyposis (FAP) looking for potential ways to prevent colorectal cancer in the general population at an earlier more treatable stage. The researchers’ findings are published in GUT. “Colorectal cancer is the third most common […]
Tags: center for individualized medicine, colon cancer, Dr. Niloy "Jewel" Samadder, genomics, individualized medicine, medical research
July 20, 2022
2022 Gerstner Awardee to investigate dual CAR-T cell therapy for multiple myeloma cancer
By Susan Murphy
Dr. Sakemura is working to advance immunotherapy efficacy in multiple myeloma cancer by uncovering treatment resistance mechanisms and developing a more potent immunotherapy approach. His strategy focuses on simultaneously targeting cancer cells and the ecosystem surrounding each tumor, known as the tumor microenvironment.
Tags: center for individualized medicine, Genetics, genomics, individualized medicine, medical research, Multiple Myeloma
July 15, 2022
BA.5 omicron variant fueling latest COVID-19 surge
By Susan Murphy
A team of scientists within Mayo Clinic’s COVID-19 Sequencing Command Center is at the forefront of tracing the genetic evolution of SARS-CoV-2, the virus that causes COVID-19. The extensive research and surveillance operation involves conducting hundreds of sequences of the COVID-19 virus each week.
Tags: center for individualized medicine, covid-19, Genetics, genomics, individualized medicine, medical research
June 29, 2022
Mayo study validates threshold to determine when an antidepressant is ineffective
By Susan Murphy
Mayo Clinic researchers have validated a threshold designed to help determine if an antidepressant used for depression is working, but not well enough to be continued.
Tags: #Dr. William Bobo, antidepressants, center for individualized medicine, depression, genomics, individualized medicine, major depressive disorder, medical research, personalized medicine
June 21, 2022
By Susan Murphy
A collaborative team of scientists led by Mayo Clinic’s Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome. Symptoms of the disorder range from speech and motor impairment to behavioral abnormalities, intellectual disability and distinctive facial features.
Tags: #neurological disorders, center for individualized medicine, Dr. Margot Cousin, gene sequencing, genomics, medical research, personalized medicine
June 13, 2022
Native American’s genetic test results at Mayo Clinic reveal surprise lineage to ancient tribe
By Susan Murphy
Mayo Clinic working to advance health equity among Native Americans, Alaska Natives Schyler Martin, a member of the Munsee Band of Mohicans in Minnesota, was surprised and excited when his recent Mayo Clinic genetic test results revealed he has distinctive DNA lineage to an ancient group of Native Americans known as the Beringians. According to […]
Tags: center for individualized medicine, DNA Testing, Dr. Konstantinos Lazaridis, Genetic Testing, Genetics, genomic medicine, individualized medicine, medical research, tapestry
May 19, 2022
Study indicates gut microbiome, host gene affect gastrointestinal disorders
In a new study published in Nature Microbiology, researchers demonstrated the power of integrating the microbiome and host gene expression data to provide insights into their combined role in gastrointestinal diseases. The microbiome consists of all microbes in the gut including bacteria, fungi, and viruses. This study focused on bacteria. “We identified a common set […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research, personalized medicine