December 23, 2022
10 significant Mayo Clinic Center for Individualized Medicine Studies of 2022
By Susan Murphy
In 2022, researchers and physicians at Mayo Clinic’s Center for Individualized Medicine blazed a trail of genomic and multi-omic research and scientific discoveries. The center’s innovative investigations hold a transformative potential to predict, prevent, treat and cure diseases using individualized medicine approaches. Here’s a look back at 10 (of many) of Mayo Clinic’s influential precision medicine research […]
Tags: center for individualized medicine, gene sequencing, genomic medicine, individualized medicine, medical research
December 16, 2022
NIH’s All of Us Research Program returns health-related DNA results to participants
The National Institutes of Health’s (NIH) All of Us Research Program has begun returning personalized health-related DNA results to more than 155,000 participants. The reports detail whether participants have an increased risk for specific health conditions and how their bodies might process certain medications. The All of Us Research Program collects participants’ blood, urine, and saliva samples. These biosamples […]
Tags: All of Us Research Program, center for individualized medicine, Genetics, mayo clinic, medical research, National Institutes of Health
December 13, 2022
Mayo researchers streamline genetic testing in heart failure clinic, improve clinical care
In a new study published in Genetics in Medicine, Mayo Clinic researchers streamlined genetic testing and counseling for patients with dilated cardiomyopathy, a type of heart muscle disease that causes the heart chambers (ventricles) to thin and stretch, growing larger. “We showed that this practice intervention increased the uptake and yield of genetic testing and […]
Tags: center for individualized medicine, Genetic Testing, mayo clinic, medical research
December 6, 2022
Mayo Clinic solves genetic mystery of woman’s lifelong ultra-rare disease
By Susan Murphy
For nearly five decades, Patti Schultz’s life was defined by mysterious and debilitating health conditions that caused her to feel isolated and discouraged. Her whirlwind of medical appointments started the day she was born, as a 2-pound preemie. Throughout her childhood, one doctor after the next was baffled by her joint pains, selective mutism, distinctive […]
Tags: #Dr. Lisa Schimmenti, center for individualized medicine, gene sequencing, genomics, medical research
November 1, 2022
By Susan Murphy
Unimaginable a decade ago, Mayo Clinic scientists have developed lab-grown miniature 3D brain models out of human cells to study opioid addiction and opioid treatment response. As a result, the team has discovered changes in specific brain cells of people diagnosed with opioid use disorder when compared to those without the addiction disease. The new […]
Tags: brain organoids, center for individualized medicine, medical research
October 10, 2022
Researchers investigate precision nutrition to improve health, prevent diseases
By Susan Murphy
Could prescribing specific nutrients, grains, fruits and vegetables tailored to a person’s DNA and other biological characteristics help improve their health? Precision nutrition is taking center stage at Mayo Clinic’s upcoming Individualizing Medicine Conference on Nov. 2-3, 2022, in Rochester, Minnesota, where some of the world’s top experts will share their knowledge of the potential […]
Tags: center for individualized medicine, Genetics, genomic medicine, genomics, medical research, precision nutrition
September 22, 2022
Mayo Clinic researchers identify drug resistance factors for advanced prostate cancer
In a new study published in Molecular Cancer Research, Mayo Clinic researchers identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. “We defined a potential strategy for both responders and nonresponders of the drug that may help men overcome resistance and prolong […]
Tags: center for individualized medicine, genomic medicine, individualized medicine, mayo clinic, medical research
September 15, 2022
Designing Personalized Vaccines to Combat Cancer
By Susan Murphy
Mayo Clinic researchers are working to develop personalized therapeutic cancer vaccines that can potentially target each person’s distinctive tumor characteristics. The new approach, built on advances in genomic research and data analytics, holds transformative potential to boost the power of the immune system to identify and attack cancer cells.
Tags: Cancer Research, cancer vaccine, center for individualized medicine, Genetics, medical research, neoantigen, personalized medicine
August 31, 2022
Critical Questions About AI: A Researcher Takes Pulse of Clinicians, Patients
By Susan Murphy
Richard Sharp, Ph.D., director of Mayo Clinic’s Biomedical Ethics Research Program, is heading a team studying what people think about medical innovations like genetic testing, neuromodulation and now AI.
Tags: center for individualized medicine, genomic medicine, medical research
August 16, 2022
Mayo Clinic researchers study rare genetic condition to tackle colorectal cancer
By Susan Murphy
By Joe Dangor Researchers from the Mayo Clinic Comprehensive Cancer Center and the Mayo Clinic Center for Individualized Medicine are studying a rare genetic condition called Familial Adenomatous Polyposis (FAP) looking for potential ways to prevent colorectal cancer in the general population at an earlier more treatable stage. The researchers’ findings are published in GUT. “Colorectal cancer is the third most common […]
Tags: center for individualized medicine, colon cancer, Dr. Niloy "Jewel" Samadder, genomics, individualized medicine, medical research